Ⅲ급 부정교합에서 두개안면 형태와 지문의 유전성향 분석
Analysis of the hereditary factor in craniofacial morphology and fingerprints in Class Ⅲ malocclusion
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성장기 부정교합 환자의 치료시 다양한 악안면 성장은 치료성패의 중요한 요소이다. 따라서 치료를 시작하기 전에 안면성장을 예측하는 것은 매우 중요하다. 본 연구는 Ⅲ급 부정교합을 보이는 아동에서 성장을 예측할 수 있는 방법들 중의 하나로 두부방사선 계측사진 분석을 통해 유전적 요소의 관련여부를 알아보고자 50가족에서 부모자식간의 악안면 형태의 상관관계를 통계학적으로 분석하였다. 또한 자식과 부모간의 지문의 형태적 연관성을 조사하고 부모자식간의 악안면 형태와 지문의 형태적 연관성과의 유전적 상관관계를 조사하여 다음과 같은 결론을 얻었다. 1. 부모자식간의 악안면 형태에서 치성관계보다는 악골관계에서 더 유전성향이 높았으며 아버지가 어머니에 비해 자식의 악골관계에 더 영향을 주었다. 2. 자식의 지문 형태는 아버지보다는 어머니와의 연관성이 더 높게 나타났다. 3. 부모와 자식간의 지문과 악안면 형태에서 유전적 상관관계가 있었으며(P<0.05-0.01), 딸보다는 아들에게서 연관성이 더 높게 나타났다.
Abstract
In growing patients with Class Ⅲ malocclusion, the various patterns of maxillofacial growth are a key element that affects the success or failure of treatment. Therefore it is important to correctly predict maxillofacial growth before initiating treatment. The purpose of this study was to find out the correlation between the maxillofacial morphology of parents and their Class Ⅲ children by analyzing lateral cephalograms and hereditary factors. Among Class Ⅲ preadolescent children, 50 families were obtained. To find out the specific hereditary factors involved, fingerprints were obtained and genetic correlation with the maxillofacial morphology was analyzed. The following conclusions were made. 1. A significant correlation (P<0.05-0.001) was found in many of the cephalometric measurements between the offspring and their parents. The correlation in the skeleton measurements was higher than in the denture measurements. The father-offspring correlation was higher than the mother-offspring correlation 2. A significant correlation (P<0.05-0.001) was found in fingerprint units between the offspring and their parents. The mother-offspring correlation was higher than the father-offspring correlation. 3. Between the maxillofacial morphology and fingerprint units, there was significant genetic correlation (P<0.05-0.01). Based on the analysis of genetic correlation, higher correlation was found in the parent-son pairing than the parent-daughter pairing.
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