Epidemiological and Clinical Characteristics of Confirmed Cases of Severe Fever With Thrombocytopenia Syndrome in Jeju Province, Korea, 2014-2018
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Objectives: Jeju Province is well known as the region showing the highest incidence of severe fever with thrombocytopenia syndrome (SFTS) in South Korea. The aim of this study was to evaluate the epidemiological and clinical characteristics of SFTS patients in Jeju Province. Methods: The primary data for this study were obtained from the Integrated Diseases and Health Control System of the Korea Centers for Disease Control and Prevention (KCDCIS). The selection criteria were confirmed cases of SFTS with a residence listed in Jeju Province at the time of diagnosis, reported to the KCDCIS between July 16, 2014 and November 30, 2018. Results: Of 55 confirmed cases of SFTS, the case fatality rate was 10.9% (95% confidence interval [CI], 4.1 to 22.2). The most common presenting symptoms at diagnosis of severe fever, myalgia, and diarrhea had incidences of 83.6% (95% Cl, 71.2 to 92.2), 45.5% (95% Cl, 32.0 to 59.5), and 40.0% (95% CI, 27.0 to 54.1), respectively. Conclusions: Compared to SFTS patients nationwide in 2013-2015, the subjects of this study exhibited a lower case fatality rate and had a lower incidence of severe fever, myalgia, and confusion.
Abstract
Objectives: Jeju Province is well known as the region showing the highest incidence of severe fever with thrombocytopenia syndrome (SFTS) in South Korea. The aim of this study was to evaluate the epidemiological and clinical characteristics of SFTS patients in Jeju Province. Methods: The primary data for this study were obtained from the Integrated Diseases and Health Control System of the Korea Centers for Disease Control and Prevention (KCDCIS). The selection criteria were confirmed cases of SFTS with a residence listed in Jeju Province at the time of diagnosis, reported to the KCDCIS between July 16, 2014 and November 30, 2018. Results: Of 55 confirmed cases of SFTS, the case fatality rate was 10.9% (95% confidence interval [CI], 4.1 to 22.2). The most common presenting symptoms at diagnosis of severe fever, myalgia, and diarrhea had incidences of 83.6% (95% Cl, 71.2 to 92.2), 45.5% (95% Cl, 32.0 to 59.5), and 40.0% (95% CI, 27.0 to 54.1), respectively. Conclusions: Compared to SFTS patients nationwide in 2013-2015, the subjects of this study exhibited a lower case fatality rate and had a lower incidence of severe fever, myalgia, and confusion.
참고문헌 (7)
- Norbert John C. Robles, "Epidemiology of severe fever and thrombocytopenia syndrome virus infection and the need for therapeutics for the prevention", Clinical and Experimental Vaccine Research, 7(1), pp.43~50 (2018), 대한백신학회[DOI]
- Yu XJ, "Fever with thrombocytopenia associated with a novel bunyavirus in China", N Engl J Med, 364(16), pp.1523~1532 (2011)
- 배종면, "한국인과 중국인 중증열성혈소판감소증 환자간 임상증상의 차이", 대한응급의학회지, 30(3), pp.205~207 (2019), 대한응급의학회
- Guo CT, "Epidemiological and clinical characteristics of severe fever with thrombocytopenia syndrome(SFTS)in China : an integrated data analysis", Epidemiol Infect, 144(6), pp.1345~1354 (2016)
- Choi SJ, "Severe fever with thrombocytopenia syndrome in South Korea, 2013-2015", PLoS Negl Trop Dis, 10(12), pp.e0005264~ (2016)
- 배종면, "Epidemiological characteristics of scrub typhus on the Jeju Island", Epidemiology and Health, 39, pp.1~2 (2017), 한국역학회[DOI]
- "Report of second infection on severe fever and thrombocytopenia syndrome"[URL]