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Severe Fever with Thrombocytopenia Syndrome Virus in Ticks in the Republic of Korea

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초록

Severe fever with thrombocytopenia syndrome virus (SFTSV) is a zoonotic, tick-borne RNA virus of the genus Bandavirus (Family Phenuiviridae), mainly reported in China, Japan, and the Republic of Korea (Korea). For the purpose of this study, a total of 3,898 adult and nymphal ticks of species Haemaphysalis longicornis (94.2%), Haemaphysalis flava (5.0%), Ixodes nipponensis (0.8%), and 1 specimen of Ixodes ovatus, were collected from the Deogyusan National Park, Korea, between April 2016 and June 2018. A single-step reverse transcriptase–nested PCR was performed, targeting the S segment of the SFTSV RNA. Total infection rate (IR) of SFTSV in individual ticks was found to be 6.0%. Based on developmental stages, IR was 5.3% in adults and 6.0% in nymphs. The S segment sequences obtained from PCR were divided into 17 haplotypes. All haplotypes were phylogenetically clustered into clades B-2 and B-3, with 92.7% sequences in B-2 and 7.3% in B-3. These observations indicate that the Korean SFTSV strains were closer to the Japanese than the Chinese strains. Further epidemiological studies are necessary to better understand the characteristics of the Korean SFTSV and its transmission cycle in the ecosystem.

Abstract

Severe fever with thrombocytopenia syndrome virus (SFTSV) is a zoonotic, tick-borne RNA virus of the genus Bandavirus (Family Phenuiviridae), mainly reported in China, Japan, and the Republic of Korea (Korea). For the purpose of this study, a total of 3,898 adult and nymphal ticks of species Haemaphysalis longicornis (94.2%), Haemaphysalis flava (5.0%), Ixodes nipponensis (0.8%), and 1 specimen of Ixodes ovatus, were collected from the Deogyusan National Park, Korea, between April 2016 and June 2018. A single-step reverse transcriptase–nested PCR was performed, targeting the S segment of the SFTSV RNA. Total infection rate (IR) of SFTSV in individual ticks was found to be 6.0%. Based on developmental stages, IR was 5.3% in adults and 6.0% in nymphs. The S segment sequences obtained from PCR were divided into 17 haplotypes. All haplotypes were phylogenetically clustered into clades B-2 and B-3, with 92.7% sequences in B-2 and 7.3% in B-3. These observations indicate that the Korean SFTSV strains were closer to the Japanese than the Chinese strains. Further epidemiological studies are necessary to better understand the characteristics of the Korean SFTSV and its transmission cycle in the ecosystem.

참고문헌 (31)

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관련 논문AI추천

No detection of severe Fever with thrombocytopenia syndrome virus from ixodid ticks collected in seoulHee-Jin Ham, Jungim Jang, Sukju Jo, Sung-min Choi대한기생충학ㆍ열대의학회 · Parasites, Hosts and Diseases2014 · 제52권 제2호Distribution of Tick Vectors of Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) Collected from Four Environments in Jeju박철, 서민영, 송현제, 이혁재, 정경아대한임상검사과학회 · 대한임상검사과학회지2020 · 제52권 제4호지리산둘레길에서 채집한 참진드기의 분포와 참진드기에서의 중증열성혈소판감소증후군바이러스 검출송병준, 송현제, 양수인, 임현철, 전두영, 하태만한국동물위생학회 · 한국동물위생학회지2016 · 제39권 제2호Hard Ticks as Vectors Tested Negative for Severe Fever with Trombocytopenia Syndrome in Ganghwa-do, Korea during 2019-2020진경, 고연자, 공영우, 권문주, 권형욱, 김동수, 박영일, 송재용, 안성규, 이진영, 임정환, 조중희대한기생충학ㆍ열대의학회 · Parasites, Hosts and Diseases2021 · 제59권 제3호Four Year Surveillance of the Vector Hard Ticks for SFTS, Ganghwa-do, Republic of Korea박영일, 안성규, 이욱교, 이진영, Haneul Jung, Hojong Jun, Jong Yul Roh, Kwangsig Joo, Mun Ju Kwon, Myung-Deok Kim-Jeon, Seo Hye Park, Seung Jegal, Tong-Soo Kim, Young-Woo Gong대한기생충학ㆍ열대의학회 · Parasites, Hosts and Diseases2019 · 제57권 제6호Epidemiological and Clinical Characteristics of Confirmed Cases of Severe Fever With Thrombocytopenia Syndrome in Jeju Province, Korea, 2014-2018배종면, Jinhee Kim대한예방의학회 · 예방의학회지2019 · 제52권 제3호

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