국소 피부감염증에서 ITS 염기서열 분석을 이용한Scedosporium apiospermum 동정의 예
A Case of Localized Skin Infection Due to Scedosporium apiospermum Diagnosed by DNA Sequencing of the Internal Transcribed Spacer Region
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초록
Scedosporium apiospermum is an asexual state of Pseudallescheria boydii which has been isolatedfrom soil, sewage, and decaying vegetation. It can cause cutaneous infections by traumatic implantationof the contaminant due to penetrating injury. This ubiquitous fungus cause not only mycetoma, but alsoinfections of variety of body sites including the skin. The localized skin infection due to this organismis much rare than mycetoma. We report a case of cutaneous S. apiospermum infection occurred in80-year-old male. The skin lesion was manifested by a 8.0 × 4.0 cm-sized erythematous plaque withpustules and crusts on the dorsum of right hand. The fungal culture from the biopsy specimen onSabouraud's dextrose agar showed white to gray colored cottony colonies of S. apiospermum. Thenucleotide sequence of internal transcribed spacer for clinical isolate was identical to that of S. apiospermum strain IHEM 23829. The patient was treated with oral fluconazole for 3 months.
Abstract
Scedosporium apiospermum is an asexual state of Pseudallescheria boydii which has been isolatedfrom soil, sewage, and decaying vegetation. It can cause cutaneous infections by traumatic implantationof the contaminant due to penetrating injury. This ubiquitous fungus cause not only mycetoma, but alsoinfections of variety of body sites including the skin. The localized skin infection due to this organismis much rare than mycetoma. We report a case of cutaneous S. apiospermum infection occurred in80-year-old male. The skin lesion was manifested by a 8.0 × 4.0 cm-sized erythematous plaque withpustules and crusts on the dorsum of right hand. The fungal culture from the biopsy specimen onSabouraud's dextrose agar showed white to gray colored cottony colonies of S. apiospermum. Thenucleotide sequence of internal transcribed spacer for clinical isolate was identical to that of S. apiospermum strain IHEM 23829. The patient was treated with oral fluconazole for 3 months.
참고문헌 (17)
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