본문 바로가기
KERD
논문KCI 등재

Voriconazole로 치료한 Scedosporium apiospermum 에 의한 피부감염증 1예

A Case of Skin Infection due to Scedosporium apiospermum Treated with Voriconazole

2

조회

0

다운로드

5

인용

0

참고문헌

키워드

주제분류미생물학

초록

Scedosporium(S.) apiospermum has been isolated from polluted water, soil, sewage and potted plants in a hospital with low virulence. The localized skin infection due to S. apiospermum is rare and usually results from traumatic implantation of contaminated material due to a penetrating injury. We report a case of skin infection due to S. apiospermum in a 78-year-old female. She had multiple nodules, pustules and exudative ulcerative lesions at the right forearm. Cultured isolation for definitive diagnosis showed typical S. apiospermum. Treatment was started with itraconazole effectively, but skin lesions were recurred after 4 months, and then cured with voriconazole with no recurrence.

Abstract

Scedosporium(S.) apiospermum has been isolated from polluted water, soil, sewage and potted plants in a hospital with low virulence. The localized skin infection due to S. apiospermum is rare and usually results from traumatic implantation of contaminated material due to a penetrating injury. We report a case of skin infection due to S. apiospermum in a 78-year-old female. She had multiple nodules, pustules and exudative ulcerative lesions at the right forearm. Cultured isolation for definitive diagnosis showed typical S. apiospermum. Treatment was started with itraconazole effectively, but skin lesions were recurred after 4 months, and then cured with voriconazole with no recurrence.

참고문헌 (13)

  1. O'Bryan TA., "Pseudallescheriasis in the 21st century", Expert Rev Anti Infect Ther, 3, pp.765~773 (2005)
  2. Kim DJ, "A case of cutaneous Pseudallescheriasis", Kor J Med Mycol, 1, pp.101~106 (1996)
  3. Ahn BJ, "Cutaneous Pseudallescheria boydii Infection", Korean J Med Mycol, 4, pp.143~147 (1999)
  4. Kim HU, "Localized skin infection due to Scedosporium apiospermum", Br J Dermatol, 141, pp.605~606 (1999)
  5. Lee HJ, "A Case of Cutaneous Abscess Due to Scedosporium apiospermum", Korean J Dermatol, 39, pp.812~815 (2001)
  6. Im M, "A Case of Localized Skin Infection Due to Scedosporium apiospermum", Korean J Dermatol, 42, pp.1505~1507 (2004)
  7. Choi YL, "A case of cutaneous Scedosporium apiospermum infection", Korean J Dermatol, 43, pp.704~706 (2005)
  8. 이용환, "Scedosporium apiospermum에 의한 국소피부감염증 1예", 대한피부과학회지, 45(10), pp.1060~1063 (2007), 대한피부과학회
  9. Chung JW, "A Case of Disseminated Infection Due to Scedosporium apiospermum in a Liver-transplantation Recipient", Korean J Lab Med, 25, pp.421~424 (2005)
  10. Morera-Lopez Y, "In vitro susceptibility of fungal and yeast clinical isolates to itraconazole and voriconazole", Rev Iberoam Micol, 22, pp.105~109 (2005)
  11. Espinel-Ingroff A, "Activities of voriconazole, itraconazole and amphotericin B in vitro against 590 moulds from 323 patients in the voriconazole Phase III clinical studies", J Antimicrob Chemother, 61, pp.616~620 (2008)
  12. Troke P, "Treatment of Scedosporiosis with Voriconazole: Clinical Experience with 107 Patients", Antimicrob Agents Chemother, 52, pp.1743~1750 (2008)
  13. Schaenman JM, "Scedosporium apiospermum soft tissue infection successfully treated with voriconazole: potential pitfalls in the transition from intravenous to oral therapy", J Clin Microbiol, 43, pp.973~977 (2005)

관련 논문AI추천

이 간행물의 다른 논문 (5건)