모야모야 질병에서 관류 자기공명영상의 임상적 적용에 대한 연구
Clinical Application of Moya-Moya Disease in Perfusion Magnetic Resonance Imaging
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초록
The purpose of this study was to evaluate clinical application for patients with moyamoyadisease by using perfusion MRI. The study targeted 22 moyamoya disease patients that included 9 men and13 women in average age of 9.3 years and age range of 4~22 years. Perfusion MRI was obtained byscanning the 7.5cm part in the upward direction from the base of cerebellum before being processed forpost-treatment, which led to acquisition of four map images for cerebral blood volume (CBV), cerebralblood flow (CBF), mean transit time (MTT) for contrast medium, and time to peak (TTP) for contrastmedium. Lesions were examined in the CBV, CBF, MTT, and TTP maps of the perfusion MRI while theMTT and TTP were measured in the lesion parts and the normal and symmetric parts for comparison ofdifferences. Perfusion defects were recognizable in all of the four maps of the perfusion MRI while delayin the MTT and TTP was conspicuous in the parts where perfusion defects were recognized. Therefore,perfusion MRI is useful for diagnosis and effective treatment for patient with moyamoya disease, whichcan be applied to clinical practice.
Abstract
The purpose of this study was to evaluate clinical application for patients with moyamoyadisease by using perfusion MRI. The study targeted 22 moyamoya disease patients that included 9 men and13 women in average age of 9.3 years and age range of 4~22 years. Perfusion MRI was obtained byscanning the 7.5cm part in the upward direction from the base of cerebellum before being processed forpost-treatment, which led to acquisition of four map images for cerebral blood volume (CBV), cerebralblood flow (CBF), mean transit time (MTT) for contrast medium, and time to peak (TTP) for contrastmedium. Lesions were examined in the CBV, CBF, MTT, and TTP maps of the perfusion MRI while theMTT and TTP were measured in the lesion parts and the normal and symmetric parts for comparison ofdifferences. Perfusion defects were recognizable in all of the four maps of the perfusion MRI while delayin the MTT and TTP was conspicuous in the parts where perfusion defects were recognized. Therefore,perfusion MRI is useful for diagnosis and effective treatment for patient with moyamoya disease, whichcan be applied to clinical practice.
참고문헌 (18)
- 유병규, "자기공명영상학" (2003), 대학서림
- Edelman, R. R, , Radiology, 176(1), pp.211~220 (1990)
- Maeda, M, , Radiology, 189(1), pp.227~232 (1993)
- Rempp, K. A., , Radiology, 193(3), pp.637~641 (1994)
- 이종석, "초급성 허혈성 뇌졸중에서 관류 전산화단층촬영의 임상적 적용에 대한 연구", 의학물리, 18(3), pp.149~160 (2007), 한국의학물리학회
- Zieler, K. L., , Cirs. Res, 10, pp.393~407 (1962)
- Ostergaard, L., , Magn. Res. Med, 36(5), pp.715~725 (1996)
- Tzika, A. A., , Pediatr. Radiol, 27(9), pp.727~735 (1997)
- Tsuchiya, K., , AJNR, 19(2), pp.211~216 (1998)
- Aronen, H. J., , Acta. Radiol, 36(5), pp.520~528 (1995)
- DRCMR Annual Report 2002, "Andersen, I. K", ~, pp.18-19 (2002) (2002)
- Barbier, E. L., , Magn. Reson. Imaging, 13(4), pp.496~520 (2001)
- Toga, A. W., , Nat. Rev. Neurosci, 4(1), pp.37~48 (2003)
- Wong, J. C., , AJR, 174(4), pp.1147~1157 (2000)
- Petrella, J. R., , AJR, 175(1), pp.207~219 (2000)
- Neumann-Haefelin, T., , Stroke, 30(8), pp.1591~1597 (1999)
- Wintermark, M., , Eur. Radiol, 11(7), pp.1120~1230 (2001)
- Mayer, T. E., , AJNR, 21(8), pp.1441~1449 (2000)