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일과성허혈발작에서 초기 관류강조영상의 유용성

Significance of Early Perfusion Weighted MRI for the Diagnosis of TIA

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초록

We report on three patients with transient focal neurologic deficits that completely resolved. In all cases, initial perfusion-weighted imaging (PWI) performed 1 hour after being free of symptoms showed a defect in the time-to-peak (TTP) map in the area with normal diffusion-weight imaging (DWI) findings. After 24 hours, DWI showed a high signal intensity in exactly the same area as the TTP defect. Therefore, early PWI provides a rapid evaluation of cerebral hemodynamics in transient ischemic attack.

Abstract

We report on three patients with transient focal neurologic deficits that completely resolved. In all cases, initial perfusion-weighted imaging (PWI) performed 1 hour after being free of symptoms showed a defect in the time-to-peak (TTP) map in the area with normal diffusion-weight imaging (DWI) findings. After 24 hours, DWI showed a high signal intensity in exactly the same area as the TTP defect. Therefore, early PWI provides a rapid evaluation of cerebral hemodynamics in transient ischemic attack.

참고문헌 (10)

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  6. Shih LC, "Perfusion-weighted magnetic resonance imaging thresholds identifying core, irreversibly infarcted tissue", Stroke, 34, pp.1425~1430 (2003)
  7. Warach S, "The redefinition of TIA: the uses and limitations of DWI in acute ischemic cerebrovascular syndromes", Neurology, 62, pp.359~360 (2004)
  8. Krol AL, "Perfusion MRI abnormalities in speech or motor transient ischemic attack patients", Stroke, 36, pp.2487~2489 (2005)
  9. Poppe AY, "Normal magnetic resonance perfusion-weighted imaging in lacunar infarcts predicts a low risk of early deterioration", Cerebrovasc Dis, 28, pp.151~156 (2009)
  10. del Zoppo GJ, "Cerebral microvessel responses to focal ischemia", J Cereb Blood Flow Metab, 23, pp.879~894 (2003)

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