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Monte Carlo-based identification of electron and proton edges for calibration of miniaturized tissue equivalent proportional counter

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주제분류원자력공학

초록

Miniaturized tissue equivalent proportional counters (mini-TEPCs) are proper for radiation dosimetry in medical application because the small size of the dosimeter could prevent pile-up effect under the high intensity of therapeutic beam. However, traditional methods of calibrating mini-TEPCs using internal alpha sources are not feasible due to their small size. In this study, we investigated the use of electron and proton edges on Monte Carlo-generated lineal energy spectra as markers for calibrating a 0.9 mm diameter and length mini-TEPC. Three possible markers for each spectrum were calculated and compared using different simulation tools. Our simulations showed that the electron edge markers were more consistent across different simulation tools than the proton edge markers, which showed greater variation due to differences in the microdosimetric spectra. In most cases, the second marker, yδδ, had the smallest uncertainty. Our findings suggest that the lineal energy spectra from mini-TEPCs can be calibrated using Monte Carlo simulations that closely resemble real-world detector and source geometries.

Abstract

Miniaturized tissue equivalent proportional counters (mini-TEPCs) are proper for radiation dosimetry in medical application because the small size of the dosimeter could prevent pile-up effect under the high intensity of therapeutic beam. However, traditional methods of calibrating mini-TEPCs using internal alpha sources are not feasible due to their small size. In this study, we investigated the use of electron and proton edges on Monte Carlo-generated lineal energy spectra as markers for calibrating a 0.9 mm diameter and length mini-TEPC. Three possible markers for each spectrum were calculated and compared using different simulation tools. Our simulations showed that the electron edge markers were more consistent across different simulation tools than the proton edge markers, which showed greater variation due to differences in the microdosimetric spectra. In most cases, the second marker, yδδ, had the smallest uncertainty. Our findings suggest that the lineal energy spectra from mini-TEPCs can be calibrated using Monte Carlo simulations that closely resemble real-world detector and source geometries.

참고문헌 (17)

  1. Fawaz Ali, "Design and Characterization of Next-Generation Tissue Equivalent Proportional Counters for Use in Low Energy Neutron Fields", Faculty of Energy Systems and Nuclear Science, pp.2014
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  3. S. Rollet, "Monte Carlo simulation of mini TEPC microdosimetric spectra : influence of low energy electrons", Radiat. Meas, 45, pp.1330~1333 (2010)
  4. Chuan-Jong Tung, "Microdosimetric relative biological effectiveness of therapeutic proton beams", Biomed. J, 38, pp.5~ (2015)
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  6. "NIST"[URL]
  7. V. Conte, "Lineal energy calibration of mini tissue-equivalent gas-proportional counters(TEPC)", AIP Conf. Proc, 1530, pp.171~ (2013)
  8. A. Bianchi, "Microdosimetry with a sealed mini-TEPC and a silicon telescope at a clinical proton SOBP of CATANA", Radiat. Phys. Chem, 171, pp.108730~ (2020)
  9. V. Conte, "Mini-TEPC microdosimetric study of carbon ion therapeutic beams at CNAO", EPJ Web Conf, 151, pp.01012~ (2017)
  10. "NIST"[URL]
  11. J. Malimban, "Characterization of a new tissue equivalent proportional counter for dosimetry of neutron and photon fields : comparison of measurements and Monte Carlo simulations", Phys. Med. Biol, 64, pp.17~ (2019)
  12. Simulation Of Neutron And Gamma Ray Emission From Fission And Photofission, "M. J´erˆome, Verbeke", ~, pp.UCRL-AR-228618 (2014)
  13. Henri P. Gavin, "The Levenberg-Marquardt Algorithm for Nonlinear Least Squareds Curve-Fitting Problems", Dept. Of Civil and Environmental Engineering, pp.2020
  14. Quick-Start Guide to Low-Energy Photon, "Electron Transport in MCNP6", H. G. Hughes, 2013
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  16. "NIST"[URL]
  17. Delia Perez-Nunez, "and implementation of spherical tissue-equivalent proportional counter", Radiat. Prot, 168, pp.21~28 (2009)

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