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Thromboprophylaxis for Deep Vein Thrombosis and Pulmonary Embolism after Total Joint Arthroplasty in a Low Incidence Population

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초록

Postoperative venous thromboembolism is one of the most serious complications following total joint arthroplasty. Pharmacological and mechanical prophylaxis methods are used to reduce the risk of postoperative symptomatic deep vein thrombosis and pulmonary embolism. Use of pharmacological prophylaxis requires a fine balance between the efficacy of the drug in preventing deep vein thrombosis and the adverse effects associated with the use of these drugs. In regions with a low prevalence of deep vein thrombosis such as Korea, there might be a question whether the benefits of using pharmacological prophylaxis outweigh the risks involved. The current article reviews the need for thromboprophylaxis, guidelines, problems with the guidelines, pharmacological prophylaxis use, and the current scenario of deep vein thrombosis, and discusses whether the use of pharmacological prophylaxis should be mandatory in low incidence populations.

Abstract

Postoperative venous thromboembolism is one of the most serious complications following total joint arthroplasty. Pharmacological and mechanical prophylaxis methods are used to reduce the risk of postoperative symptomatic deep vein thrombosis and pulmonary embolism. Use of pharmacological prophylaxis requires a fine balance between the efficacy of the drug in preventing deep vein thrombosis and the adverse effects associated with the use of these drugs. In regions with a low prevalence of deep vein thrombosis such as Korea, there might be a question whether the benefits of using pharmacological prophylaxis outweigh the risks involved. The current article reviews the need for thromboprophylaxis, guidelines, problems with the guidelines, pharmacological prophylaxis use, and the current scenario of deep vein thrombosis, and discusses whether the use of pharmacological prophylaxis should be mandatory in low incidence populations.

참고문헌 (81)

  1. Geerts WH, "American College of Chest Physicians. Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)", Chest, 133(6 Suppl), pp.381S~453S (2008)
  2. Lachiewicz PF, "Prevention of symptomatic pulmonary embolism in patients undergoing total hip and knee arthroplasty : clinical guideline of the American Academy of Orthopaedic Surgeons", Instr Course Lect, 58, pp.795~804 (2009)
  3. Hill J, "Reducing the risk of venous thromboembolism(deep vein thrombosis and pulmonary embolism)in inpatients having surgery : summary of NICE guidance", BMJ, 334, pp.1053~1054 (2007)
  4. Cushner FD, "Unanswered questions, unmet needs in venous thromboprophylaxis", Orthopedics, 32(12 Suppl), pp.62~66 (2009)
  5. Freedman KB, "A meta-analysis of thromboembolic prophylaxis following elective total hip arthroplasty", J Bone Joint Surg Am, 82, pp.929~938 (2000)
  6. Cohen AT, "Extended thromboprophylaxis with low molecular weight heparin reduces symptomatic venous thromboembolism following lower limb arthroplasty : a meta-analysis", Thromb Haemost, 85, pp.940~941 (2001)
  7. Huisman MV, "Enoxaparin versus dabigatran or rivaroxaban for thromboprophylaxis after hip or knee arthroplasty : results of separate pooled analyses of phase III multicenter randomized trials", Circ Cardiovasc Qual Outcomes, 3, pp.652~660 (2010)
  8. Warwick D, "New concepts in orthopaedic thromboprophylaxis", J Bone Joint Surg Br, 86, pp.788~792 (2004)
  9. Kanchanabat B, "Systematic review and meta-analysis on the rate of postoperative venous thromboembolism in orthopaedic surgery in Asian patients without thromboprophylaxis", Br J Surg, 98, pp.1356~1364 (2011)
  10. Fujita S, "Deep venous thrombosis after total hip or total knee arthroplasty in patients in Japan", Clin Orthop Relat Res, 375, pp.168~174 (2000)
  11. Kim YH, "Incidence and natural history of deep-vein thrombosis after total hip arthroplasty : a prospective and randomised clinical study", J Bone Joint Surg Br, 85, pp.661~665 (2003)
  12. Ko PS, "Deep venous thrombosis after total hip or knee arthroplasty in a"low-risk"Chinese population", J Arthroplasty, 18, pp.174~179 (2003)
  13. Sudo A, "The incidence of deep vein thrombosis after hip and knee arthroplasties in Japanese patients : a prospective study", J Orthop Surg(Hong Kong), 11, pp.174~177 (2003)
  14. Yoo MC, "Deep vein thrombosis after total hip arthroplasty in Korean patients and D-dimer as a screening tool", Arch Orthop Trauma Surg, 129, pp.887~894 (2009)
  15. Wong KL, "Incidence of deep vein thrombosis following total hip arthroplasty: a Doppler ultrasonographic study", J Orthop Surg (Hong Kong), 19, pp.50~53 (2011)
  16. Fong YK, "Use of low molecular weight heparin for prevention of deep vein thrombosis in total knee arthroplasty : a study of its efficacy in an Asian population", Ann Acad Med Singapore, 29, pp.439~441 (2000)
  17. Wang CJ, "Clinical significance of muscular deep-vein thrombosis after total knee arthroplasty", Chang Gung Med J, 30, pp.41~46 (2007)
  18. Kim YH, "Factors leading to decreased rates of deep vein thrombosis and pulmonary embolism after total knee arthroplasty", J Arthroplasty, 22, pp.974~980 (2007)
  19. Chen CJ, "The value of D-dimer in the detection of early deep-vein thrombosis after total knee arthroplasty in Asian patients : a cohort study", Thromb J, 6, pp.5~ (2008)
  20. Chin PL, "Thromboembolic prophylaxis for total knee arthroplasty in Asian patients : a randomised controlled trial", J Orthop Surg(Hong Kong), 17, pp.1~5 (2009)
  21. Kim KI, "Recent Korean perspective of deep vein thrombosis after total knee arthroplasty", J Arthroplasty, 26, pp.1112~1116 (2011)
  22. Lee WS, "The incidence of pulmonary embolism and deep vein thrombosis after knee arthroplasty in Asians remains low : a meta-analysis", Clin Orthop Relat Res, 471, pp.1523~1532 (2013)
  23. Kim YH, "Factors leading to low prevalence of DVT and pulmonary embolismafter THA : analysis of genetic and prothrombotic factors", Clin Orthop Relat Res, 465, pp.33~39 (2007)
  24. Kim YH, "Factors leading to low incidence of deep vein thrombosis after cementless and cemented total knee arthroplasty", Clin Orthop Relat Res, 273, pp.119~124 (1991)
  25. Stein PD, "Pulmonary thromboembolism in Asians", Pacific Islanders in the United States : analysis of data from the National Hospital Discharge Survey and the United States Bureau of the Census, 2004, pp.116, 435~442
  26. Leizorovicz A, "Epidemiology of post-operative venous thromboembolism in Asian patients : results of the SMART venography study", Haematologica, 92, pp.1194~1200 (2007)
  27. Warwick D, "Orthopaedic thromboprophylaxis : limitations of current guidelines", J Bone Joint Surg Br, 90, pp.127~132 (2008)
  28. Schulman S, "American College of Chest Physicians. Hemorrhagic complications of anticoagulant and thrombolytic treatment: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)", Chest, 133(6 Suppl), pp.257S~298S (2008)
  29. Falck-Ytter Y, "American College of Chest Physicians. Prevention of VTE in orthopedic surgery patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines", Chest, 141(2 Suppl), pp.e278S~e325S (2012)
  30. Mont MA, "Preventing venous thromboembolic disease in patients undergoing elective hip and knee arthroplasty", J Am Acad Orthop Surg, 19, pp.768~776 (2011)
  31. Lieberman JR, "The new AAOS clinical practice guidelines on venous thromboembolic prophylaxis : how to adapt them to your practice", J Am Acad Orthop Surg, 19, pp.717~721 (2011)
  32. Lieberman JR, "American College of Chest Physicians evidence-based guidelines for venous thromboembolic prophylaxis : the guideline wars are over", J Am Acad Orthop Surg, 20, pp.333~335 (2012)
  33. Burnett RS, "Failure of the American College of Chest Physicians-1A protocol for lovenox in clinical outcomes for thromboembolic prophylaxis", J Arthroplasty, 22, pp.317~324 (2007)
  34. Walsh M, "Relative risk factors for requirement of blood transfusion after total hip arthroplasty", J Arthroplasty, 22, pp.1162~1167 (2007)
  35. Schulman S, "Subcommittee on Control of Anticoagulation of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. Definition of major bleeding in clinical investigations of antihemostatic medicinal products in surgical patients", J Thromb Haemost, 8, pp.202~204 (2010)
  36. Sachs RA, "Does anticoagulation do more harm than good? A comparison of patients treated without prophylaxis and patients treated with low-dose warfarin after total knee arthroplasty", J Arthroplasty, 18, pp.389~395 (2003)
  37. Fitzgerald RH Jr, "Prevention of venous thromboembolic disease following primary total knee arthroplasty : a randomized, multicenter, open-label, parallel-group comparison of enoxaparin and warfarin", J Bone Joint Surg Am, 83, pp.900~906 (2001)
  38. Patel VP, "Factors associated with prolonged wound drainage after primary total hip and knee arthroplasty", J Bone Joint Surg Am, 89, pp.33~38 (2007)
  39. Parvizi J, "Does “excessive” anticoagulation predispose to periprosthetic infection?", J Arthroplasty, 22(6 Suppl 2), pp.24~28 (2007)
  40. Keays AC, "The effect of anticoagulation on the restoration of range of motion after total knee arthroplasty : enoxaparin versus aspirin", J Arthroplasty, 18, pp.180~185 (2003)
  41. Raskob GE, "Controversies in timing of the first dose of anticoagulant prophylaxis against venous thromboembolism after major orthopedic surgery", Chest, 124(6 Suppl), pp.379S~385S (2003)
  42. Strebel N, "Preoperative or postoperative start of prophylaxis for venous thromboembolism with low-molecular-weight heparin in elective hip surgery?", Arch Intern Med, 162, pp.1451~1456 (2002)
  43. Kwong LM, "Thromboprophylaxis dosing: therelationship between timing of first administration, efficacy, and safety", Am J Orthop (Belle Mead NJ), 31(11 Suppl), pp.16~20 (2002)
  44. Eikelboom JW, "Extended-duration prophylaxis against venous thromboembolism after total hip or knee replacement : a meta-analysis of the randomised trials", Lancet, 358, pp.9~15 (2001)
  45. Kearon C, "Duration of venous thromboembolism prophylaxis after surgery", Chest, 124(6 Suppl), pp.386S~392S (2003)
  46. White RH, "Incidence and time course of thromboembolic outcomes following total hip or knee arthroplasty", Arch Intern Med, 158, pp.1525~1531 (1998)
  47. Douketis JD, "Short-duration prophylaxis against venous thromboembolism after total hip or knee replacement : a meta-analysis of prospective studies investigating symptomatic outcomes", Arch Intern Med, 162, pp.1465~1471 (2002)
  48. Lie SA, "Early postoperative mortality after 67, 548 total hip replacements : causes of death and thromboprophylaxis in 68 hospitals in Norway from 1987 to 1999", Acta Orthop Scand, 73, pp.392~399 (2002)
  49. Howe CT, "The natural history of deep-vein thrombosis", Br J Surg, 56, pp.625~ (1969)
  50. Solis MM, "Lavender RC, Barnes RW. Is anticoagulation indicated for asymptomatic postoperative calf vein thrombosis?", J Vasc Surg, 16, pp.414~419 (1992)
  51. Amin AN, "Inpatient thromboprophylaxis use in U.S. hospitals: adherence to the seventh American College of Chest Physician’s recommendations for at-risk medical and surgical patients", J Hosp Med, 4, pp.E15~E21 (2009)
  52. Sharif KM, "Implementation of the NICE guidelines for venous thromboprophylaxis : a national survey of hip surgeons", Hip Int, 19, pp.58~63 (2009)
  53. Struijk-Mulder MC, "Comparing consensus guidelines on thromboprophylaxis in orthopedic surgery", J Thromb Haemost, 8, pp.678~683 (2010)
  54. Callaghan JJ, "American Colleg of Chest Physicians. Prophylaxis for thromboembolic disease: recommendations from the American College of Chest Physicians: are they appropriate for orthopaedic surgery?", J Arthroplasty, 20, pp.273~274 (2005)
  55. Pearse EO, "Early mobilisation after conventional knee replacement may reduce the risk of postoperative venous thromboembolism", J Bone Joint Surg Br, 89, pp.316~322 (2007)
  56. Chandrasekaran S, "Early mobilization after total knee replacement reduces the incidence of deep venous thrombosis", ANZ J Surg, 79, pp.526~529 (2009)
  57. Husted H, "Low risk of thromboembolic complications after fast-track hip and knee arthroplasty", Acta Orthop, 81, pp.599~605 (2010)
  58. Daniel J, "Multimodal thromboprophylaxis following primary hip arthroplasty : the role of adjuvant intermittent pneumatic calf compression", J Bone Joint Surg Br, 90, pp.562~569 (2008)
  59. Pitto RP, "Foot pumps without graduated compression stockings for prevention of deep-vein thrombosis in total joint replacement: efficacy, safety and patient compliance. A comparative, prospective clinical trial", Int Orthop, 32, pp.331~336 (2008)
  60. Yokote R, "Is routine chemical thromboprophylaxis after total hip replacement really necessary in a Japanese population?", J Bone Joint Surg Br, 93, pp.251~256 (2011)
  61. Pitto RP, "Mechanical prophylaxis of deep-vein thrombosis after total hip replacement a randomised clinical trial", J Bone Joint Surg Br, 86, pp.639~642 (2004)
  62. Sharrock NE, "Effects of epidural anesthesia on the incidence of deep-vein thrombosis after total knee arthroplasty", J Bone Joint Surg Am, 73, pp.502~506 (1991)
  63. Modig J, "Thromboembolism after total hip replacement : role of epidural and general anesthesia", Anesth Analg, 62, pp.174~180 (1983)
  64. Modig J, "The role of lumbar epidural anaesthesia as antithrombotic prophylaxis in total hip replacement", Acta Chir Scand, 151, pp.589~594 (1985)
  65. Ranawat AS, "Pain management and accelerated rehabilitation for total hip and total knee arthroplasty", J Arthroplasty, 22(7 Suppl 3), pp.12~15 (2007)
  66. Paul JE, "Femoral nerve block improves analgesia outcomes after total knee arthroplasty : a meta-analysis of randomized controlled trials", Anesthesiology, 113, pp.1144~1162 (2010)
  67. Busch CA, "The efficacy of periarticular multimodal drug infiltration in total hip arthroplasty", Clin Orthop Relat Res, 468, pp.2152~2159 (2010)
  68. Dorr LD, "Multimodal thromboprophylaxis for total hip and knee arthroplasty based on risk assessment", J Bone Joint Surg Am, 89, pp.2648~2657 (2007)
  69. Maheshwari AV, "Multimodal pain management after total hip and knee arthroplasty at the Ranawat Orthopaedic Center", Clin Orthop Relat Res, 467, pp.1418~1423 (2009)
  70. Salvati EA, "Multimodal prophylaxis of venous thrombosis", Am J Orthop (Belle Mead NJ), 31(9 Suppl), pp.4~11 (2002)
  71. Murray DW, "Thromboprophylaxis and death after total hip replacement", J Bone Joint Surg Br, 78, pp.863~870 (1996)
  72. Howie C, "Venous thromboembolism associated with hip and knee replacement over a ten-year period : a population-based study", J Bone Joint Surg Br, 87, pp.1675~1680 (2005)
  73. Khatod M, "Pulmonary embolism prophylaxis in more than 30,000 total knee arthroplasty patients: is there a best choice?", J Arthroplasty, 27, pp.167~172 (2012)
  74. Sharrock NE, "Potent anticoagulants are associated with a higher all-cause mortality rate after hip and knee arthroplasty", Clin Orthop Relat Res, 466, pp.714~721 (2008)
  75. Kessler DP, "Effects of the medical liability system in Australia, the UK, and the USA", Lancet, 368, pp.240~246 (2006)
  76. Lachiewicz PF, "Comparison of ACCP and AAOS guidelines for VTE prophylaxis after total hip and total knee arthroplasty", Orthopedics, 32(12 Suppl), pp.74~78 (2009)
  77. Piovella F, "Deep-vein thrombosis rates after major orthopedic surgery in Asia : an epidemiological study based on postoperative screening with centrally adjudicated bilateral venography", J Thromb Haemost, 3, pp.2664~2670 (2005)
  78. Leizorovicz A, "Epidemiology of venous thromboembolism in Asian patients undergoing major orthopedic surgery without thromboprophylaxis : the SMART study", J Thromb Haemost, 3, pp.28~34 (2005)
  79. Parvataneni HK, "Controlling pain after total hip and knee arthroplasty using a multimodal protocol with local periarticular injections: a prospective randomized study", J Arthroplasty, 22(6 Suppl 2), pp.33~38 (2007)
  80. Cohn SL., "Prophylaxis of venous thromboembolism in the US: improving hospital performance", J Thromb Haemost, 7, pp.1437~1445 (2009)
  81. Grimshaw JM, "Changing provider behavior: an overview of systematic reviews of interventions", Med Care, 39(8 Suppl 2), pp.II2~II45 (2001)

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