Deep Vein Thrombosis Prophylaxis after Total Hip Arthroplasty in Asian Patients
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초록
In Western patient populations, the reported incidence of imaging-demonstrated deep vein thrombosis (DVT) after total hip arthroplasty (THA) is as high as 70% without prophylaxis. The reported rates of symptomatic pulmonary embolism (PE) after THA in recent studies range from 0.6% to 1.5%, and the risk of fatal PE ranges from 0.11% to 0.19% in the absence of prophylaxis. Predisposing factors to DVT in western patients include advanced age, previous venous insufficiency, osteoarthritis, obesity, hyperlipidemia, dietary and genetic factors. However, Asian patients who have undergone THA have a strikingly low prevalence of DVT and virtually no postoperative PE. Some authors suggest low clinical prothrombotic risk factors and the absence of some DVTrelated genetic factors in Asian patient populations decrease the risk of DVT, PE or both. In Korea, the prevalence of DVT after THA without thromboprophylaxis have ranges from 6.8% to 43.8%, and asymptomatic PE have ranges from 0% to 12.9%; there have been only two reported cases of fatal PE. Deep-wound infections resulting from postoperative hematomas or prolonged wound drainage have been reported with routine thromboprophylaxis. The prevalence of DVT differs varies based on patient ethnicity. Guidelines for the use of thromboprophylaxis were altered and focus on the potential value of outcomes compared with possible complications (e.g., bleeding).
Abstract
In Western patient populations, the reported incidence of imaging-demonstrated deep vein thrombosis (DVT) after total hip arthroplasty (THA) is as high as 70% without prophylaxis. The reported rates of symptomatic pulmonary embolism (PE) after THA in recent studies range from 0.6% to 1.5%, and the risk of fatal PE ranges from 0.11% to 0.19% in the absence of prophylaxis. Predisposing factors to DVT in western patients include advanced age, previous venous insufficiency, osteoarthritis, obesity, hyperlipidemia, dietary and genetic factors. However, Asian patients who have undergone THA have a strikingly low prevalence of DVT and virtually no postoperative PE. Some authors suggest low clinical prothrombotic risk factors and the absence of some DVTrelated genetic factors in Asian patient populations decrease the risk of DVT, PE or both. In Korea, the prevalence of DVT after THA without thromboprophylaxis have ranges from 6.8% to 43.8%, and asymptomatic PE have ranges from 0% to 12.9%; there have been only two reported cases of fatal PE. Deep-wound infections resulting from postoperative hematomas or prolonged wound drainage have been reported with routine thromboprophylaxis. The prevalence of DVT differs varies based on patient ethnicity. Guidelines for the use of thromboprophylaxis were altered and focus on the potential value of outcomes compared with possible complications (e.g., bleeding).
참고문헌 (36)
- Morris GK, "Prevention of deep-vein thrombosis by low-dose heparin in patients undergoing total hip replacement", Lancet, 2, pp.797~800 (1974)
- Fender D, "Mortality and fatal pulmonary embolism after primary total hip replacement. Results from a regional hip register", J Bone Joint Surg Br, 79, pp.896~899 (1997)
- Pellegrini VD Jr, "The John Charnley Award. Natural history of thromboembolic disease after total hip arthroplasty", Clin Orthop Relat Res, (333), pp.27~40 (1996)
- Park YS., "Guideline for the prophylaxis of venous thromboembolism in hip surgery patients", J Korean Orthop Assoc, 46, pp.95~98 (2011)
- Westrich GH, "Correlation of thrombophilia and hypofibrinolysis with pulmonary embolism following total hip arthroplasty:an analysis of genetic factors", J Bone Joint Surg Am, 84-A, pp.2161~2167 (2002)
- Zivelin A, "A single genetic origin for the common prothrombotic G20210A polymorphism in the prothrombin gene", Blood, 92, pp.1119~1124 (1998)
- Kim YH, "Incidence and natural history of deep-vein thrombosis after total hip arthroplasty. A prospective and randomised clinical study", J Bone Joint Surg Br, 85, pp.661~665 (2003)
- Kang BJ, "Deep venous thrombosis and pulmonary embolism are uncommon in East Asian patients after total hip arthroplasty", Clin Orthop Relat Res, 469, pp.3423~3428 (2011)
- Klatsky AL, "Risk of pulmonary embolism and", or deep venous thrombosis in Asian-Americans, 2000, pp.85, 1334~1337
- Nandi P, "Incidence of postoperative deep vein thrombosis in Hong Kong Chinese", Br J Surg, 67, pp.251~253 (1980)
- Kim YH, "John Charnley Award. Factors leading to low prevalence of DVT and pulmonary embolism after THA: analysis of genetic and prothrombotic factors", Clin Orthop Relat Res, 465, pp.33~39 (2007)
- Hwang DS, "Deep venoud thrombosis after hip arthroplasty", J Korean Orthop Assoc, 32, pp.554~564 (1997)
- Yoo MC, "Deep vein thrombosis and pulmonary embolism after cementless total hip arthroplasty", J Korean Orthop Assoc, 33, pp.1672~1680 (1998)
- Evarts CM, "Prevention of thromboembolic disease after elective surgery of the hip", J Bone Joint Surg Am, 53, pp.1271~1280 (1971)
- Paiement GD, "Routine use of adjusted low-dose warfarin to prevent venous thromboembolism after total hip replacement", J Bone Joint Surg Am, 75, pp.893~898 (1993)
- Thromboembolic Risk Factors(THRIFT)Consensus Group, "Risk of and prophylaxis for venous thromboembolism in hospital patients", BMJ, 305, pp.567~574 (1992)
- Johnson R, "Pulmonary embolism and its prophylaxis following the Charnley total hip replacement", Clin Orthop Relat Res, (127), pp.123~132 (1977)
- Freedman KB, "meta-analysis of thromboembolic prophylaxis following elective total hip arthroplasty", J Bone Joint Surg Am, 82-A, pp.929~938 (2000)
- Murray DW, "Thromboprophylaxis and death after total hip replacement", J Bone Joint Surg Br, 78, pp.863~870 (1996)
- Geerts WH, "Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines", Chest, 133(6 Suppl), pp.381S~453S (2008)
- Chau KY, "Clinicopathological pattern of pulmonary thromboembolism in Chinese autopsy patients : comparison with Caucasian series", Pathology, 29, pp.263~266 (1997)
- Chumnijarakij T, "Postoperative thrombosis in Thai women", Lancet, 1, pp.1357~1358 (1975)
- Tso SC, "Deep vein thrombosis and changes in coagulation and fibrinolysis after gynaecological operations in Chinese: the effect of oral contraceptives and malignant disease", Br J Haematol, 46, pp.603~612 (1980)
- Wåhlander K, "Factor V Leiden (G1691A) and prothrombin gene G20210A mutations as potential risk factors for venous thromboembolism after total hip or total knee replacement surgery", Thromb Haemost, 87, pp.580~585 (2002)
- Woo KS, "The prevalence and pattern of pulmonary thromboembolism in the Chinese in Hong Kong", Int J Cardiol, 20, pp.373~380 (1988)
- Balasa VV, "The relationship of mutations in the MTHFR, prothrombin, and PAI-1 genes to plasma levels of homocysteine, prothrombin, and PAI-1in children and adults", Thromb Haemost, 81, pp.739~744 (1999)
- Levine MN, "Hemorrhagic complications of anticoagulant treatment: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy", Chest, 126(3 Suppl), pp.287S~310S (2004)
- Salvati EA, "The John Charnley Award: heritable thrombophilia and development of thromboembolic disease after total hip arthroplasty", Clin Orthop Relat Res, 441, pp.40~55 (2005)
- Parvizi J, "Does “excessive” anticoagulation predispose to periprosthetic infection?", J Arthroplasty, 22(6 Suppl 2), pp.24~28 (2007)
- Parvizi J, "Aggressive anticoagulation after TJA: an evaluation of the ACCP guidelines for thromboprophylaxis", J Long Term Eff Med Implants, 17, pp.359~365 (2007)
- Colwell CW Jr., "Rationale for thromboprophylaxis in lower joint arthroplasty", Am J Orthop (Belle Mead NJ), 36(9 Suppl), pp.11~13 (2007)
- Fitzgerald RH Jr., "Controversies in the prevention of deep vein thrombosis with total hip arthroplasty", Orthopedics, (17 Suppl), pp.8~10 (1994)
- Patel VP, "Factors associated with prolonged wound drainage after primary total hip and knee arthroplasty", J Bone Joint Surg Am, 89, pp.33~38 (2007)
- Falck-Ytter Y, "Prevention of VTE in orthopedic surgery patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines", Chest, 141(2 Suppl), pp.e278S~325S (2012)
- Callaghan JJ, "Prophylaxis for thromboembolic disease: recommendations from the American College of Chest Physicians--are they appropriate for orthopaedic surgery?", J Arthroplasty, 20, pp.273~274 (2005)
- Lieberman JR, "Venous thromboembolism prophylaxis in total hip arthroplasty and total knee arthroplasty patients: from guidelines to practice", J Am Acad Orthop Surg, 25, pp.789~798 (2017)