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무산소성운동이 혈중 백혈구 수, 호중구 활성산소종 생성 및 젖산농도에 미치는 영향

Effects of anaerobic exercise on circulating leukocytes, reactive oxygen species production in neutrophilis and lactate concentration in human

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이 연구의 목적은 무산소운동이 백혈구수, 호중구 ROS 생성 및 젖산농도에 미치는 영향에 대해 검토하였다. 일반 성인남자 10명을 연구대상으로 하였으며, 무산소운동은 자전거 에르고미터를 이용하여 체중 당 부하강도 0.075 kp로서10초간 전력 페달링 운동을 50초간의 휴식시간을 두고 연속적으로 5회 실시하였다. 백혈구수, 호중구 ROS 생성, 호중구 대비ROS 생성, 적혈구수, 호중구수, 간상핵구수, 분엽핵구수, 혈색소양, 헤마토크리트, 평균 혈구용적치 및 젖산은 무산소운동전및 직후, 운동 30분, 60분 및 120분후에 각각 측정하였다. 백혈구수 및 호중구 대비 ROS 생성은 운동전과 비교해서 운동직후(p=.038) 및 운동 120분후에 유의하게 증가하였다(p=.035, p=.027 respectively). 호중구수(p=.029), 간상핵구수(p=.029), 분엽핵구수(p=.032) 및 호중구 ROS 생성은 운동전과 비교해서 운동 120분후에 유의하게 증가하였다(p=.039). 혈중 젖산농도는 운동전과 비교해서 운동직후(p=.021) 및 운동 30후(p=.041)에 유의하게 증가하였다. 이상의 결과, 이 연구에서는 단시간고강도의 무산소운동에 있어서도 호중구 ROS 생성이 증가한다는 것을 확인하였다.

Abstract

The purpose of this study was to investigate the effects of anaerobic exercise on circulating leukocytes, reactive oxygen species production in neutrophilis and lactate concentration in human. All subjects (n=10) was performed cycle ergometer anaerobic exercise (10 seconds ⨯ 5 sets, rest for 50 seconds between each set) at load intensity 0.075 kp per weight. Changes in circulating leukocyte numbers, reactive oxygen species (ROS) production in neutrophilis, ROS per neutrophilis, red blood cell, neutrophilis, band form, segmented leukocyte, Hb, Hct, MCV and lactic acid was measured before, immediately after, 30, 60 and 120 minutes after the cycle ergometer anaerobic exercise. circulating leukocyte number and reactive oxygen species production per neutrophilis were significantly increased immediately after (p=.038) and after 120 minutes of anaerobic exercise (p=.035,p=.027 respectively) compared with before anaerobic exercise. Neutrophilis (p=.029), band form (p=.029), segmented leukocyte (p=.032),and reactive oxygen species production in neutrophilis were significantly increased after 120 minutes (p=.039) of anaerobic exercise compared with before anaerobic exercise. Lactic acid was significantly increased immediately after (p=.021) and after 30 minutes (p=.041)of anaerobic exercise compared with before anaerobic exercise. These results confirmed that anaerobic exercise increase reactive oxygen species production in neutrophilis.

참고문헌 (42)

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