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젊은 성인의 신체활동 수준과 동맥경직도, 대뇌 혈류량, 인지기능 간 관련성

The Relationship of Physical Activity Level With Arterial Stiffness, Cerebral Blood Flow, and Cognitive Function in Young Adults

김진수|박신영|임명주|이의영|황문현|이루다
한국운동생리학회|2021.11|운동과학 (Exercise Science)|제30권 제4호|pp. 527-536

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키워드

인지기능신체활동Physical activityCognitive function동맥경직도Arterial stiffnessCerebral blood flow대뇌 혈류량

초록

PURPOSE: This study aimed to investigate the relationship of physical activity level with arterial stiffness, cerebral blood flow, and cognitive function in young adults. METHODS: Forty-six young adults participated in this cross-sectional study. Physical activity levels were assessed for seven consecutive days using accelerometers. To assess arterial stiffness, the carotid-femoral artery pulse wave velocity (cfPWV) and augmentation index (AIx) were measured. Cognitive function was assessed using the Stroop Color-Word test, and cerebral blood flow was evaluated using near-infrared spectroscopy devices during the cognitive function test. RESULTS: AIx was inversely associated with axis-1 counts, vector magnitude counts, moderate-intensity physical activity (MPA) time, and moderate-to-vigorous intensity physical activity (MVPA) time (r≤-0.31, p≤.04). The AIx adjusted to the heart rate of 75 beats per minute was inversely correlated with axis-1 counts, vector magnitude counts, step counts, MPA time, and MVPA time (r≤-0.33, p≤.03). There was no relationship between cfPWV and physical activity level parameters (r≤0.10, p≥.51). The difference between oxygenated and deoxygenated hemoglobin levels was positively related to axis-1 counts, step counts, MPA time, and MVPA time (r≥0.31, p≤.04). Regarding cognitive function, the response time for the presented words was negatively associated with step counts (r=-0.42, p<.01) and MPA time (r=-0.29, p=.048), and response time on the presented words with matched color was negatively related to step counts (r=-0.31, p=.04). CONCLUSIONS: More physically active adults are more likely to have lower arterial stiffness, increased brain oxygenation, and better cognitive function, even if they are young and healthy.

Abstract

PURPOSE: This study aimed to investigate the relationship of physical activity level with arterial stiffness, cerebral blood flow, and cognitive function in young adults. METHODS: Forty-six young adults participated in this cross-sectional study. Physical activity levels were assessed for seven consecutive days using accelerometers. To assess arterial stiffness, the carotid-femoral artery pulse wave velocity (cfPWV) and augmentation index (AIx) were measured. Cognitive function was assessed using the Stroop Color-Word test, and cerebral blood flow was evaluated using near-infrared spectroscopy devices during the cognitive function test. RESULTS: AIx was inversely associated with axis-1 counts, vector magnitude counts, moderate-intensity physical activity (MPA) time, and moderate-to-vigorous intensity physical activity (MVPA) time (r≤-0.31, p≤.04). The AIx adjusted to the heart rate of 75 beats per minute was inversely correlated with axis-1 counts, vector magnitude counts, step counts, MPA time, and MVPA time (r≤-0.33, p≤.03). There was no relationship between cfPWV and physical activity level parameters (r≤0.10, p≥.51). The difference between oxygenated and deoxygenated hemoglobin levels was positively related to axis-1 counts, step counts, MPA time, and MVPA time (r≥0.31, p≤.04). Regarding cognitive function, the response time for the presented words was negatively associated with step counts (r=-0.42, p<.01) and MPA time (r=-0.29, p=.048), and response time on the presented words with matched color was negatively related to step counts (r=-0.31, p=.04). CONCLUSIONS: More physically active adults are more likely to have lower arterial stiffness, increased brain oxygenation, and better cognitive function, even if they are young and healthy.

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