렙틴, 수용성 렙틴 수용체 및 자유렙틴지수를 이용한 발레무용수의 에너지 결핍정도 평가
Estimation of the Extent of Energy Deficiency in Ballet Dancers using Serum Leptin, Soluble Leptin Receptor, and Free Leptin Index
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민경화. 렙틴, 수용성렙틴 수용체 및 자유렙틴지수를 이용한 발레무용수의 에너지 결핍정도 평가. 운동과학, 제15권 제3호. 213-228, 2006. 본 연구의 목적은 신체의 에너지 상태에 따라 민감하게 변하는 호르몬인 렙틴과 수용성 렙틴 수용체(sOb-R) 및 자유렙틴지수(FLI)를 이용하여 발레무용수의 에너지 결핍정도를 평가하는데 있다. 피험자들(연령: 20~29세)은 서울지역에 거주하는 프로발레무용수(PB집단)와 발레전공 여대생(UB집단) 및 일반 여대생(대조군, US집단) 등 3집단으로서 각 10명씩 구분하여 총 30명을 임의선정 하였다. 체지방율(%BF)과 BMR은 생체전기저항법을 이용하여 구하였고 렙틴과 sOb-R의 농도는 각각 RIA법과 ELISA법으로 측정하였다. 혈중 렙틴농도와 FLI는 US > UB > PB 순이었고, sOb-R은 그 반대 순서였는데 이는 세 집단중 PB집단이 상대적으로 가장 저영양 상태에 있음을 시사한다. 주당 운동시간은 렙틴 및 FLI 값과 부적 상관관계를 나타냈으나 sOb-R과는 정적 상관관계를 나타냈는데 이는 만성적인 영양결핍상태에 있는 발레무용수들이 지속적인 운동을 실시할 경우 에너지 부족을 촉진시켜 athlete triad와 같은 위험한 상태에 놓일 수 있음을 의미한다. 체지방율에 대해 FLI를 나타낸 그림에서 %BF≤ 25% 및 FLI ≤ 10% 인 곳은 에너지 결핍 영역이며 특히 %BF ≤ 20% 및 FLI ≤ 6.5% 인 영역은 신경성 식욕부진증의 발생확율이 높은 영역(anorectic zone)으로서 이 영역에 속하는 사람들에 대해서는 특별관리가 필요하다고 사료된다. 이상의 정보들은 athlete triad 위험군을 미리 예측할 때 유용하게 사용될 수 있을 것이다.
Abstract
Min, K.H. Estimation of the Extent of Energy Deficiency in Ballet Dancers using Serum Leptin, Soluble Leptin Receptor, and Free Leptin Index. Exercise Science. 15(3): 213-228, 2006. The purpose of the present study was to estimate the extent of energy deficiency in ballet dancers using serum leptin, soluble leptin receptor(sOb-R), and free leptin Index(FLI). For this purpose, the subjects of 30 females(age range, 20~29) were selected as follows: the pro-ballerinas(PB, n=10), the ballet-major female undergraduates (UB, n=10) and the female undergraduates(US, n=10; controls). The percent body fat(%BF) and BMR were obtained by bioimpedance analysis and the concentrations of serum leptin and sOb-R were measured by RIA and ELISA, respectively. The rank orders of leptin concentrations and the FLI values are US > UB > PB, whereas the sOb-R concentrations show the reverse order. This means the PB group is under the most energy-deficient state among three groups. The exercise time per a week of testees was negatively correlated with the values of leptin and FLI, whereas positively correlated with that of sOb-R, which shows ballet dancers could be placed in the dangerous state such as athlete triad due to the stimulation of energy depletion if the exercise would be performed persistently in the chronic malnutrition condition. In the diagram of %BF and FLI, the area{%BF≤ 25%, FLI≤ 10%} was reveled as the energy- deficient zone and people who belong to the anorectic zone{%BF≤ 20%, FLI≤ 6.5%} should be cared with the special attention. The above informations could be used to predict the candidates of athlete triad beforehand.
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