비만아동의 최대운동후 부교감신경계 활성도와심혈관계 질환 위험 인자 및 염증지표와의 관련성
The Relationship Between Parasympathetic Nervous System Activity after Peak Exercise, Cardiovascular Disease Risk Factors and Inflammatory Markers in Obese Children.
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초록
본 연구의 목적은 초등학교 4-6학년(11세~13세) 학생을 대상으로 비만집단(n=21), 일반집단(n=19) 그리고 주 4회, 2년 이상 운동에 참여하고 있는 운동집단(n=20)의 부교감신경계 활성도 및 심혈관계 질환 위험 인자, 염증지표와 비만이 어떠한 관련이 있는지 확인하고, 부교감신경계 활성 지표인 HRR이 아동의 심혈관계 질환 위험 인자 및 염증지표와 어떠한 관련성이 있는지 확인하고자 하였다. 모든 피검자들은 Bruce 프로토콜을 사용하여 GXT 검사를 시행하였다. 회복시심박수(HRR)는 운동부하검사 직후 운동 시 도달한 최고 심박수에서 회복시 1분, 2분 또는 3분 동안의 심박수를 뺀 값으로 정의하였다. 회복단계를 위한 프로토콜은 트레드밀이 완전히 멈출 때까지 최대운동 후 30 초간 가볍게 걷기를 시행하였다. 비만집단은 일반 및 운동집단에 비해 부교감신경계 활성도가 저조하고 심폐체력이 낮게 나타났으며, 심혈관계 질환 위험인자 및 염증지표가 높게 나타난 것으로 보아 아동에게 있어서 비만이 이러한 요인들에 부정적인 영향을 미친 것으로 판단된다. 또한 본 연구를 통하여 부교감신경계 활성도(HRR)와 심혈관계 질환 위험 인자 및 염증지표와의 상호관련성이 나타난 것은 부교감신경 활성지표인 회복시심박수가 아동의 심장질환에 대한 위험도를 조기에 발견하기위한 지표로 활용 될 수 있음을 확인 할 수 있었다.
Abstract
The purpose of this study is to confirm which influence the obesity has upon parasympathetic nervous system activation, which relationship HRR as parasympathetic nervous system activity index has with children's cardiovascular disease risk factors and inflammatory markers, and which influence the parasympathetic nervous system has upon relationship between cardiorespiratory fitness and inflammatory marker, in obesity group(OG:10.6±.5, n=21), general group(NG:10.8±8, n=19), and exercise group(EG:11.1 ±.8, n=20). All subjects were carried out GXT(graded exercise test) by using Bruce protocol. HRR immediately after exercise stress testing defined as the decrease in heart rate from peak exercise to 1, 2 and 3 minutes into recovery(peak heart rate minus 1, 2 and 3 minutes heart rate of recovery) was determined. The protocol for recovery stage includes a 30-second lightly walk after peak exercise as the treadmill decelerates to a complete stop. As a result, this study came to the following findings:the obesity group was indicated to be lower in the parasympathetic nervous system activation and in the CRF compared to the NG and EG. In light of having been shown to be high in cardiovascular disease risk factors and inflammatory markers, the children's obesity is judged to have negative influence upon these factors. Also, what the correlation was indicated between parasympathetic nervous system activation(HRR) and cardiovascular disease risk factors & inflammatory markers through this study could be confirmed that the heart rate recovery, which is parasympathetic nervous system activity index, can be utilized as a marker for early discovering children's cardiovascular disease risk level.
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