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신체활동 수준이 심혈관계와 자율신경기능에 미치는 영향

Influence of Physical Activity Level on Cardiovascular and Autonomic Nerve Function

이승호|김진수|이루다|이의영|황문현|박신영
한국운동생리학회|2023.02|운동과학 (Exercise Science)|제32권 제1호|pp. 111-119

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참고문헌

키워드

신체활동Physical activity동맥경직도arterial stiffness중심혈류역학자율신경기능central hemodynamicsautonomic nerve function

초록

PURPOSE: The purpose of this study was to demonstrate differences in cardiovascular and autonomic nerve function among physical activity levels and associations between physical activity level and cardiovascular and autonomic nerve function. METHODS: Sixty-six healthy young adults voluntarily participated in this cross-sectional study. Physical activity levels were assessed using triaxial accelerometers for 7 consecutive days. Central hemodynamics and arterial stiffness were measured using the Sphygomo- Cor Xcel system. Autonomic nerve function was assessed by heart rate variability. RESULTS: The highest tertile group of the total quantity of physical activity had higher lnRMSSD than did the lowest tertile group (p=0.047). The augmentation index adjusted for heart rate at 75 beats per min (AIx@75) was lower in the highest tertile group of vig- orous-intensity physical activity than in the lowest tertile group (p=0.012). Moreover, AIx@75 was negatively associated with vigorous-intensity physical activity (r=-0.27, p=0.028). CONCLUSIONS: High levels of physical activity contribute to the dominance of parasympathetic nerve activity at rest. Increased engagement in vigorous-intensity physical activity can help reduce arterial pulse wave reflection, an independent risk factor for cardiovascular diseases, even in healthy young adults.

Abstract

PURPOSE: The purpose of this study was to demonstrate differences in cardiovascular and autonomic nerve function among physical activity levels and associations between physical activity level and cardiovascular and autonomic nerve function. METHODS: Sixty-six healthy young adults voluntarily participated in this cross-sectional study. Physical activity levels were assessed using triaxial accelerometers for 7 consecutive days. Central hemodynamics and arterial stiffness were measured using the Sphygomo- Cor Xcel system. Autonomic nerve function was assessed by heart rate variability. RESULTS: The highest tertile group of the total quantity of physical activity had higher lnRMSSD than did the lowest tertile group (p=0.047). The augmentation index adjusted for heart rate at 75 beats per min (AIx@75) was lower in the highest tertile group of vig- orous-intensity physical activity than in the lowest tertile group (p=0.012). Moreover, AIx@75 was negatively associated with vigorous-intensity physical activity (r=-0.27, p=0.028). CONCLUSIONS: High levels of physical activity contribute to the dominance of parasympathetic nerve activity at rest. Increased engagement in vigorous-intensity physical activity can help reduce arterial pulse wave reflection, an independent risk factor for cardiovascular diseases, even in healthy young adults.

참고문헌 (46)

  1. Gaziano TA, "Growing Epidemic of Coronary Heart Disease in Low-and Middle-Income Countries", Curr Prob Cardiology, 35(2), pp.72~115 (2010)
  2. Mc Namara K, "Cardiovascular disease as a leading cause of death : how are pharmacists getting involved?", Integr Pharm Res Pra, 8, pp.1~11 (2019)
  3. Mittal BV, "Hypertension in the Developing World : Challenges and Opportunities", Am J Kidney Dis, 55(3), pp.590~598 (2010)
  4. Kumar A, "The impact of obesity on cardiovascular disease risk factor", Asian J Med Sci, 10(1), pp.1~12 (2019)
  5. Kumma WP, "Modifiable cardiovascular disease risk factors among adults in southern Ethiopia : a community-based cross-sectional study(vol 12, e057930, 2022)", BMJ Open, 12(4) (2022)
  6. Myers J, "Exercise and cardiovascular health", Circulation, 107(1), pp.e2~e5 (2003)
  7. Nystoriak MA, "Cardiovascular effects and benefits of exercise", Front Cardiovasc Med, 5, pp.135~ (2018)
  8. Vlachopoulos C, "Prediction of Cardiovascular Events and All-Cause Mortality With Arterial Stiffness A Systematic Review and Meta-Analysis", J Am Coll Cardiol, 55(13), pp.1318~1327 (2010)
  9. Safar ME, "Obesity, arterial stiffness, and cardiovascular risk", J Am Soc Nephrol, 17(4), pp.S109~S111 (2006)
  10. 박원일, "The Role of Habitual Physical Activity on Arterial Stiffness in Elderly Individuals: A Systematic Review and Meta-Analysis", Physical Activity and Nutrition, 21(4), pp.16~21 (2017), 한국운동영양학회[DOI]
  11. Mahmud A, "Effect of smoking on arterial stiffness and pulse pressure amplification", Hypertension, 41(1), pp.183~187 (2003)
  12. Lee H-Y, "Aging and arterial stiffness", Circ J, 74(11), pp.2257~2262 (2010)
  13. Liatis S, "Cardiac Autonomic Function Correlates with Arterial Stiffness in the Early Stage of Type 1 Diabetes", Experimental Diabetes Research (2011)
  14. Lacolley P, "Mechanisms of Arterial Stiffening From Mechanotransduction to Epigenetics", Arterioscl Throm Vas, 40(5), pp.1055~1062 (2020)
  15. Urbina EM, "Impact of multiple cardiovascular risk factors on brachial artery distensibility in young adults-The Bogalusa Heart Study", Am J Hypertens, 18(6), pp.767~771 (2005)
  16. Camm AJ, "Heart rate variability-Standards of measurement, physiological interpretation, and clinical use", Circulation, 93(5), pp.1043~1065 (1996)
  17. Al Hazzouri AZ, "Reduced Heart Rate Variability Is Associated With Worse Cognitive Performance in Elderly Mexican Americans", Hypertension, 63(1), pp.181~187 (2014)
  18. Thayer JF, "The relationship of autonomic imbalance, heart rate variability and cardiovascular disease risk factors", Int J Cardiol, 141(2), pp.122~131 (2010)
  19. Saz-Lara A, "The Acute Effect of Exercise on Arterial Stiffness in Healthy Subjects : A Meta-Analysis", J Clin Med, 10(2) (2021)
  20. Madden KM, "Short-Term Aerobic Exercise Reduces Arterial Stiffness in Older Adults With Type 2 Diabetes, Hypertension, and Hypercholesterolemia", Diabetes Care, 32(8), pp.1531~1535 (2009)
  21. Stamatelopoulos K, "Physical activity is associated with lower arterial stiffness in normalweight postmenopausal women", J Clin Hypertens, 22(9), pp.1682~1690 (2020)
  22. Wichi RB, "A Brief Review of Chronic Exercise Intervention to Prevent Autonomic Nervous System Changes during the Aging Process", Clinics, 64(3), pp.253~258 (2009)
  23. Tornberg J, "Physical activity is associated with cardiac autonomic function in adolescent men", PLos One, 14(9) (2019)
  24. Edwards NM, "Physical activity is independently associated with multiple measures of arterial stiffness in adolescents and young adults", Metabolism, 61(6), pp.869~872 (2012)
  25. Fernberg U, "Higher Total Physical Activity is Associated with Lower Arterial Stiffness in Swedish, Young Adults : The Cross-Sectional Lifestyle, Biomarkers, and Atherosclerosis Study", Vasc Health Risk Man, 17, pp.175~185 (2021)
  26. Tebar WR, "Relationship between domains of physical activity and cardiac autonomic modulation in adults : a cross-sectional study", Sci Rep, 10(1) (2020)
  27. Freedson PS, "Calibration of the Computer Science and Applications, Inc. accelerometer", Med Sci Sport Exer, 30(5), pp.777~781 (1998)
  28. Endes S, "Physical activity is associated with lower arterial stiffness in older adults : results of the SAPALDIA 3 Cohort Study", Eur J Epidemiol, 31(3), pp.275~285 (2016)
  29. 이현주, "노인에서 동맥경화지표와 단문형 국제신체활동설문지(IPAQ­SF)로 평가한 신체활동수준과의 관계", 대한지역사회영양학회지, 25(3), pp.236~245 (2020), 대한지역사회영양학회
  30. May R, "Vigorous physical activity predicts higher heart rate variability among younger adults", J Physiol Anthropol, 36 (2017)
  31. Joseph G, "Dose-Response Association Between Level of Physical Activity and Mortality in Normal, Elevated, and High Blood Pressure", Hypertension, 74(6), pp.1307~1315 (2019)
  32. Hamer M, "The anti-hypertensive effects of exercise-Integrating acute and chronic mechanisms", Sports Med, 36(2), pp.109~116 (2006)
  33. Gomez-Marcos MA, "Relationship between objectively measured physical activity and vascular structure and function in adults", Atherosclerosis, 234(2), pp.366~372 (2014)
  34. Van De Laar RJ, "Lifetime vigorous but not light-to-moderate habitual physical activity impacts favorably on carotid stiffness in young adults : the amsterdam growth and health longitudinal study", Hypertension, 55(1), pp.33~39 (2010)
  35. Buch AN, "Mortality, cardiac vagal control and physical training–what’s the link?", Exp Physiol, 87(4), pp.423~435 (2002)
  36. Hambrecht R, "Effect of exercise on coronary endothelial function in patients with coronary artery disease", New Engl J Med, 342(7), pp.454~460 (2000)
  37. Kingwell BA, "Nitric oxide as a metabolic regulator during exercise : Effects of training in health and disease", Clin Exp Pharmacol P, 27(4), pp.239~250 (2000)
  38. Chowdhary S, "Role of nitric oxide in the regulation of cardiovascular autonomic control", Clin Sci, 97(1), pp.5~17 (1999)
  39. Townend JN, "Modulation of Cardiac Autonomic Control in Humans by Angiotensin-II", Hypertension, 25(6), pp.1270~1275 (1995)
  40. Gielen S, "Cardiovascular Effects of Exercise Training Molecular Mechanisms", Circulation, 122(12), pp.1221~1238 (2010)
  41. Kojda G, "Molecular mechanisms of vascular adaptations to exercise. Physical activity as an effective antioxidant therapy?", Cardiovasc Res, 67(2), pp.187~197 (2005)
  42. Roque FR, "Aerobic exercise reduces oxidative stress and improves vascular changes of small mesenteric and coronary arteries in hypertension", Brit J Pharmacol, 168(3), pp.686~703 (2013)
  43. Teixeira-Lemos E, "Regular physical exercise training assists in preventing type 2 diabetes development : focus on its antioxidant and anti-inflammatory properties", Cardiovasc Diabetol, 10 (2011)
  44. Higashi Y, "Exercise and endothelial function : Role of endothelium-derived nitric oxide and oxidative stress in healthy subjects and hypertensive patients", Pharmacol Therapeut, 102(1), pp.87~96 (2004)
  45. Nyberg M, "Role of nitric oxide and prostanoids in the regulation of leg blood flow and blood pressure in humans with essential hypertension : effect of highintensity aerobic training", J Physiol-London, 590(6), pp.1481~1494 (2012)
  46. Padilla J, "Characterization of the brachial artery shear stress following walking exercise", Vasc Med, 13(2), pp.105~111 (2008)

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