가습기 살균제 제품의 건강위험 고찰 - 제품 수와 살균제 성분을 중심으로 -
Comprehensive Review on Humidifier Disinfectant (HD) Products, Focusing on the Number of Products and Their Disinfectant Type
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Objectives: No study has been conducted to review characteristics of humidifier disinfectants (HD) products, such as real numbers, levels and types of HD substances contained, or the volume marketed. We aimed to review the characteristics of HD through a literature review. Methods: We collected literature reporting the names, numbers, and ingredients of HD and discussed them with a focus on the number of HD products and the chemicals used as a disinfectant. Results: A total of eight publications has reported the names of HD brands or types of disinfectants from 2011 to 2020. To date, a total of 40 HD products have been used, excluding four products. Eight HD products used polyhexamethylene guanidine phosphate (PHMG) and 14 used a mixture of chloromethylisothiazolinone (CMIT) and methylisothiazolinone (MIT) as disinfectants. Benzalkonium chloride (BKC) and sodium dichloroisocyanurate (NaDCC) were also used as a disinfectant in several HD products. A total of 19 HD products were associated with the development of HD associated lung injury (HDLI). The Oxy Saksak HD product containing PHMG showed the highest number of HD associated health effects. The type of disinfectant from a total of 14 HD products has not been identified. Conclusions: A total of 40 HD products have been marketed in South Korea since 1994. Further studies should be conducted to identify the association of product characteristics, including type of HD ingredients, with health effects.
Abstract
Objectives: No study has been conducted to review characteristics of humidifier disinfectants (HD) products, such as real numbers, levels and types of HD substances contained, or the volume marketed. We aimed to review the characteristics of HD through a literature review. Methods: We collected literature reporting the names, numbers, and ingredients of HD and discussed them with a focus on the number of HD products and the chemicals used as a disinfectant. Results: A total of eight publications has reported the names of HD brands or types of disinfectants from 2011 to 2020. To date, a total of 40 HD products have been used, excluding four products. Eight HD products used polyhexamethylene guanidine phosphate (PHMG) and 14 used a mixture of chloromethylisothiazolinone (CMIT) and methylisothiazolinone (MIT) as disinfectants. Benzalkonium chloride (BKC) and sodium dichloroisocyanurate (NaDCC) were also used as a disinfectant in several HD products. A total of 19 HD products were associated with the development of HD associated lung injury (HDLI). The Oxy Saksak HD product containing PHMG showed the highest number of HD associated health effects. The type of disinfectant from a total of 14 HD products has not been identified. Conclusions: A total of 40 HD products have been marketed in South Korea since 1994. Further studies should be conducted to identify the association of product characteristics, including type of HD ingredients, with health effects.
참고문헌 (19)
- 박동욱, "가습기 살균제 제품에 표기된 안전보건정보 고찰", 한국환경보건학회지, 43(5), pp.349~359 (2017), 한국환경보건학회
- Physicochemical characteristics by humidifier disinfectant brands, "Park D", National Institute of Environmental Health (NIER), ~ (2017)
- Analysis of components of disinfectant contained in humidifier disinfectant products, "Special Investigation Commission on Humidifier Disinfectants and 4.16 Sewol Ferry Disasters (SICHD)", ~ (2020)
- Korea Centers for Disease Control and Prevention (KCDC), "Analytical results of the chemical components of various humidifier disinfectant brands from KCDC’s parliamentary inspection (In Korean)", Department of Epidemiology Research, ~ (2011)
- Cases of health problems due to the use of humidifier biocide, "Korean Society of Environmental Health(KSEH)", KSEH, ~ (2012)
- Field interview investigation for 30 companies to manufacture humidifier disinfectant (HD), "Ministry of Environment (MOE)", ~ (2017)
- Environmental Exposure Checklist, "The checklist for environmental exposure investigation", ~ (2013)
- Special Committee for National Investigation to find out the truth of the humidifier disinfectant accident, remedy damage, and prepare measures to prevent recurrence. National Survey Results Report, "National Assembly(NA)", ~ (2016)
- 이은선, "일반 가구의 가습기살균제 노출 특성 및 건강이상 경험과의 연관성", 한국환경보건학회지, 46(3), pp.285~296 (2020), 한국환경보건학회[DOI]
- "Comprehensive supporting portal for humidifier disinfectant victims: Statistical data"[URL]
- "Act on the Safety Management of Household Chemical Products and Biocides (No. 17326)"[URL]
- Datta S, "The eye drop preservative benzalkonium chloride potently induces mitochondrial dysfunction and preferentially affects LHON mutant cells", Investig Ophthalmol Vis Sci, 58(4), pp.2406~2412 (2017)
- "Disinfectants and Asthma"[URL]
- Zock J-P, "The use of household cleaning sprays and adult asthma : an international longitudinal study", Am J Resp Crit Care Med, 176(8), pp.735~741 (2007)
- Purohit A, "Quaternary ammonium compounds and occupational asthma", Int Arc Occup Env Hea, 73(6), pp.423~427 (2000)
- Vandenplas O, "Asthma related to cleaning agents : a clinical insight", BMJ Open, 3(9), pp.e003568~ (2013)
- Park D-U, "Types of household humidifier disinfectant and associated risk of lung injury(HDLI)in South Korea", Sci Total Environ, 596, pp.53~60 (2017)
- Ryu SH, "Humidifier disinfectant and use characteristics associated with lung injury in Korea", Indoor Air, 29(5), pp.735~747 (2019)
- Park D-U, "Properties of polyhexamethylene guanidine (PHMG) associated with fatal lung injury in Korea", Molecules, 25(14), pp.3301~ (2020)