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모유수유 중 인삼의 적응증과 용량에 관한 기존한약서 고찰

Textual Research : Indication and Dosage of Panax Ginseng during Lactation

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Purpose: To provide basic informations for guidelines of Ginseng usage during lactation. Method: Based on a regulation of scope and preparation of herbal prescriptions by Ministry of health and welfare of Korea, we selected the formulae for postpartum care and disease in 7 Korean Medical Classics. And we searched the number of formulae including Ginseng, dosage and indications of Ginseng in formulae in those books. Results: The range of Ginseng dosage during lactation from medical classics is 1.5-18.75g/day for medical purposes. Indications of Ginseng are lethargy, excessive bleeding, asthma, fever, cold, pain, dizziness, mental disorder, spasm, digestive problem, constipation, diarrhea, urinary incontinence, edema, breast engorgement, lack of breastmilk, breast ulcer, etc. But Ginseng had not been used in the case of stroke, epistaxis, beginning of mastitis, tumor of lower abdomen. Conclusions: Ginseng should be recommended less than 1.5g/d as a nutritional supplement. If breastfeeding woman wants to take Ginseng as a medication or as a tonic, she should consult with a official specialist about proper prescription and dosage instead of risky random medication.

Abstract

Purpose: To provide basic informations for guidelines of Ginseng usage during lactation. Method: Based on a regulation of scope and preparation of herbal prescriptions by Ministry of health and welfare of Korea, we selected the formulae for postpartum care and disease in 7 Korean Medical Classics. And we searched the number of formulae including Ginseng, dosage and indications of Ginseng in formulae in those books. Results: The range of Ginseng dosage during lactation from medical classics is 1.5-18.75g/day for medical purposes. Indications of Ginseng are lethargy, excessive bleeding, asthma, fever, cold, pain, dizziness, mental disorder, spasm, digestive problem, constipation, diarrhea, urinary incontinence, edema, breast engorgement, lack of breastmilk, breast ulcer, etc. But Ginseng had not been used in the case of stroke, epistaxis, beginning of mastitis, tumor of lower abdomen. Conclusions: Ginseng should be recommended less than 1.5g/d as a nutritional supplement. If breastfeeding woman wants to take Ginseng as a medication or as a tonic, she should consult with a official specialist about proper prescription and dosage instead of risky random medication.

참고문헌 (34)

  1. Walker M, "Core Curriculum for Lactation Consultant Practice", pp.333~364 (2006), Jones&Bartlett
  2. 전병선, "고려인삼의 유통 현황과 명품화 제품 개발 전략", Food Preservation and Processing Industry, 8(2), pp.47~51 (2009)
  3. Hale T., "Medications and Mother's Milk", pp.13~20 (2010), Pharmasoft Publishing
  4. Seely D., "Safety and Efficacy of Panax Ginseng during Pregnancy and Lactation", Can J Clin Parmacol, 15(1), pp.e87~e94 (2008)
  5. Wiklund IK, "Effects of a standardized ginseng extract on quality of life and physiological parameters in symptomatic postmenopausal women: a double-blind, placebo-controlled trial", Int J Clin Pharmacol Res, 19, pp.89~99 (1999)
  6. Greenspan EM, "Ginseng and vaginal bleeding", JAMA, 249, pp.2018~ (1983)
  7. Punnonen R, "Oestrogen- like effect of ginseng", Br Med J, 281, pp.1110~ (1980)
  8. Cheng TO, "Ginseng-Warfarin interaction", ACC Current Journal Review, 9(1), pp.84~ (2000)
  9. Siegel RK, "Ginseng abuse syndrome: problems with panacea", JAMA, 241(15), pp.1614~1615 (1979)
  10. 식품의약품안전청, "건강기능식품에 사용할 수 없는 원료 등에 관한 규정 일부개정고시 42", 식품의약품안전청, ~ (2008)
  11. 보건복지부, "기존한약서(보건사회부 예규 제233호, 1969)에 대한 잠정규정 개정", 보건복지부, ~ (2008)
  12. 兪孝通, "새천년 鄕藥集成方", pp.3~953 (2000), 정담출판사
  13. 李梃, "醫學入門", pp.48~605 (1998), 고려의학
  14. 許浚, "原本 東醫寶鑑", pp.72~671 (1996), 남산당
  15. 張景岳, "景岳全書" (1997), 대성문화사
  16. 龔廷賢, "壽世保元", pp.3~779 (1993), 人民衛生出版社
  17. 康命吉, "韓國醫學大系 18", pp.93~630 (1992)
  18. 黃道淵, "對譯 證脈․方藥合編", pp.51~371 (2000), 남산당
  19. "제중신편 원문 데이터베이스", 누리미디어, ~ (2003)
  20. "방약합편 원문 데이터베이스", IBOOKPIA, ~ (2002)
  21. 이선영, "수유부의 유선질환을 의미하는 한의학 용어 연구", 한국한의학연구원논문집, 16(2), pp.75~81 (2010), 한국한의학연구원
  22. "미국 약전 천연물 DB"[URL]
  23. Klein S, "The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines" (1998), The Americal Botanical Council
  24. 남기열, "인삼의 한의학적 및 현대임상적 측면에서의 복용량 검토", J Ginseng Res, 24(2), pp.99~105 (2000)
  25. 남기열, "고려인삼의 주요 효능과 그 임상적 응용", Journal of Ginseng Research, 26(3), pp.111~131 (2002), 고려인삼학회
  26. Kim SN, "Simultaneous quantification of 14 ginsenosides in Panax ginseng C.A. Meyer (Korean red ginseng) by HPLC-ELSD and its application to quality control", Journal of Pharmaceutical and Biomedical Analysis, 45(1), pp.164~170 (2007)
  27. 식품의약품 안전청, "건강기능식품의 기준 및 규격 일부개정고시 7호", 식품의약품 안전청, ~ (2010)
  28. Hwang YP, "Ginsenoside Rb1 protects against 6-hydroxydopamin -induced oxidative stress by increasing heme oxygenase-1 expression through an estrogen receptor-related PI3K", Akt, Toxicol Appl Pharmacol, pp.2010, 242(1)[DOI]
  29. Lau WS, "Ginsenoside Rg1 exerts estrogen-like activities via ligand-independent activation of ERalpha pathway", J Steroid Biochem Mol Biol, 108(1), pp.64~71 (2008)
  30. Lau WS, "Mitogen-activated protein kinase(MAPK) pathway mediates the oestrogen-like activities of ginsenoside Rg1 in human breast cancer(MCF-7) cells", Br J Pharmacol, 156(7), pp.1136~1146 (2009)
  31. Leung KW, "Ginsenoside Rb1 inhibits tube-like structure formation of endothelial cells by regulating pigment epithelium-derived factor through the oestrogen beta receptor", Br J Pharmacol, 152(2), pp.207~215 (2007)
  32. Papapetropoulos A, "A ginseng-derived oestrogen receptor beta (ERbeta) agonist, Rb1 ginsenoside, attenuates capillary morphogenesis", Br J Pharmacol, 152(2), pp.172~174 (2007)
  33. 백덕우, "인삼 Saponin이 Prolactin 분비에 미치는 효과", 생약학회지, 9(1), pp.33~39 (1978)

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