항 GD1b IgG 단일 항체와 관련된 길랭-바레 증후군으로 발현된 편평상피세포 폐암 증례
A Case of Squamous Cell Lung Cancer Representing as Guillain-Barre Syndrome Associated with Monospecific Anti-GD1b IgG
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We report a case with squamous cell lung cancer with concomitant Guillain-Barre syndrome (GBS) as a paraneoplastic syndrome. A 67-year-old patient who was previously diagnosed as metastatic squamous cell lung cancer developed mild symmetrical weakness, paresthesia and sensory ataxia. Nerve conduction study showed sensorimotor polyneuropathy. Analysis of cerebrospinal fluid showed high tilter for monospecific anti-GD1b IgG antibody without onconeuronal antibodies. After treatment with intravenous immunoglobulin, the patient’s symptoms improved. (Korean J Clin Neurophysiol 2015;17:31-34)
Abstract
We report a case with squamous cell lung cancer with concomitant Guillain-Barre syndrome (GBS) as a paraneoplastic syndrome. A 67-year-old patient who was previously diagnosed as metastatic squamous cell lung cancer developed mild symmetrical weakness, paresthesia and sensory ataxia. Nerve conduction study showed sensorimotor polyneuropathy. Analysis of cerebrospinal fluid showed high tilter for monospecific anti-GD1b IgG antibody without onconeuronal antibodies. After treatment with intravenous immunoglobulin, the patient’s symptoms improved. (Korean J Clin Neurophysiol 2015;17:31-34)
참고문헌 (10)
- Hughes RA, "Guillain-Barré syndrome", Lancet, 366, pp.1653~1666 (2005)
- Rudnicki SA, "Paraneoplastic syndromes of the peripheral nerves", Curr Opin Neurol, 18, pp.598~603 (2005)
- Graus F, "Recommended diagnostic criteria for paraneoplastic neurological syndromes", J Neurol Neurosurg Psychiatry, 75, pp.1135~1140 (2004)
- Vigliani M-C, "Risk of cancer in patients with Guillain-Barre syndrome (GBS)", J Neurol, 251, pp.321~326 (2004)
- Cicero G, "A case of guillain-barre syndrome in a patient with non small cell lung cancer treated with chemotherapy", J Chemother, 18, pp.325~327 (2006)
- Navani V, "Guillain-Barrésyndrome as a paraneoplastic manifestation of disseminated squamous cell carcinoma", BMJ Case Rep, 2013, pp.pii: bcr20~ (2013)
- Naveed S, "Guillain-Barre syndrome as a paraneoplastic manifestation of small-cell carcinoma of lung", South Med J, 103, pp.156~158 (2010)
- Windebank AJ, "Chemotherapy‐induced neuropathy", J Peripher Nerv Syst, 13, pp.27~46 (2008)
- Kusunoki S, "Monospecific anti‐GD1b IgG is required to induce rabbit ataxic neuropathy", Ann Neurol, 45, pp.400~403 (1999)
- Miyazaki T, "Guillain-Barré syndrome associated with IgG monospecific to ganglioside GD1b", Neurology, 56, pp.1227~1229 (2001)