Reference ranges for autonomic function tests in healthy korean adults
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초록
Background: The standardized autonomic function test has become widely available. However, there are no reference data for this test for the Korean population. This study explored reference data for sudomotor and cardiovagal function tests for the Korean population. Methods: The sweat volume by quantitative sudomotor axon reflex test, heart-rate response to deep breathing (HRdb), expiration:inspiration (E:I) ratio, and Valsalva ratio (VR) were measured in 297 healthy Korean volunteers aged from 20 to 69 years. Multivariate regression analysis was performed to evaluate the effects of age, sex, and body mass index on these variables. The 2.5th, 5th, 10th, 90th, 95th, and 97.5th percentile values were obtained for each investigation. Results: The sweat volume was higher in males than in females. The HRdb and E:I ratio were negatively correlated with age, and were higher in males than in females. The VR was negatively correlated with age, but it was not correlated with sex. Conclusions: This study has provided data on the reference ranges for sudomotor and cardiovagal function tests in healthy Korean adults.
Abstract
Background: The standardized autonomic function test has become widely available. However, there are no reference data for this test for the Korean population. This study explored reference data for sudomotor and cardiovagal function tests for the Korean population. Methods: The sweat volume by quantitative sudomotor axon reflex test, heart-rate response to deep breathing (HRdb), expiration:inspiration (E:I) ratio, and Valsalva ratio (VR) were measured in 297 healthy Korean volunteers aged from 20 to 69 years. Multivariate regression analysis was performed to evaluate the effects of age, sex, and body mass index on these variables. The 2.5th, 5th, 10th, 90th, 95th, and 97.5th percentile values were obtained for each investigation. Results: The sweat volume was higher in males than in females. The HRdb and E:I ratio were negatively correlated with age, and were higher in males than in females. The VR was negatively correlated with age, but it was not correlated with sex. Conclusions: This study has provided data on the reference ranges for sudomotor and cardiovagal function tests in healthy Korean adults.
참고문헌 (16)
- Phillip A. Low, "Autonomic Function Tests: Some Clinical Applications Open Access", Journal of Clinical Neurology, 9(1), pp.1~8 (2013), 대한신경과학회[DOI]
- Low PA, "Effect of age and gender on sudomotor and cardiovagal function and blood pressure response to tilt in normal subjects", Muscle Nerve, 20, pp.1561~1568 (1997)
- Sletten DM, "Relationship of Q-sweat to quantitative sudomotor axon reflex test (QSART) volumes", Muscle Nerve, 41, pp.240~246 (2010)
- Chen SF, "Sweat output measurement of the post-ganglion sudomotor response by Q-Sweat Test: a normative database of Chinese individuals", BMC Neurosci, 13, pp.62~ (2012)
- Goldstein IB, "The cardiovascular response to postural change as a function of race", Biol Psychol, 39, pp.173~186 (1995)
- Jeong H, "Effects of age, sex, and body mass index on sudomotor and cardiovagal functions in a healthy Korean population", Neurol Asia, 21, pp.255~260 (2016)
- Park KJ, "Guidelines for autonomic function test", J Pain Aut Disord, 2, pp.55~65 (2013)
- Novak P, "Quantitative autonomic testing", J Vis Exp, (53), pp.e2502~ (2011)
- Low PA, "Quantitative sudomotor axon reflex test in normal and neuropathic subjects", Ann Neurol, 14, pp.573~580 (1983)
- Low PA, "The effect of aging on cardiac autonomic and postganglionic sudomotor function", Muscle Nerve, 13, pp.152~157 (1990)
- McCance RA, "Ethnic differences in the response of the sweat glands to pilocarpine", Nature, 221, pp.378~379 (1969)
- Vinik AI, "Normative values for electrochemical skin conductances and impact of ethnicity on quantitative assessment of sudomotor function", Diabetes Technol Ther, 18, pp.391~398 (2016)
- Ewing DJ, "The value of cardiovascular autonomic function tests: 10 years experience in diabetes", Diabetes Care, 8, pp.491~498 (1985)
- Torsvik M, "Cardiovascular autonomic function tests in an African population", BMC Endocr Disord, 8, pp.19~ (2008)
- Vita G, "Cardiovascular reflex tests. Assessment of age-adjusted normal range", J Neurol Sci, 75, pp.263~274 (1986)
- Thayer JF, "The relationship of autonomic imbalance, heart rate variability and cardiovascular disease risk factors", Int J Cardiol, 141, pp.122~131 (2010)
