기립경사검사 동안 발생하는 기립 증상들과 자율신경지표들 간의 상관관계
Correlation Between Orthostatic Symptoms and Autonomic Parameters During the Head-Up Tilt Test
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Background: The aims of the present study were to identify the orthostatic symptoms occurring during the head-up tilt(HUT) test and to compare the autonomic parameters in patients with and without symptoms during the HUT test. Methods: We retrospectively collected autonomic data from patients presenting with autonomic symptoms includingorthostatic dizziness over a 1-year period. A standardized battery of autonomic tests was performed, including the HUTtest, Valsalva maneuver (VM), heart rate (HR) deep breathing test, and quantitative sudomotor axon reflex test (QSART)using Finometer devices to record the beat-to-beat blood pressure (BP) and HR response. We also investigated thepatients’ symptoms during the HUT test and compared the autonomic parameters between patients with and withoutorthostatic symptoms. Results: In total, 898 patients who submitted to autonomic function tests were included in this study. Of these, 17%(157/898) complained of various kinds of symptoms during tilting, while the remainder denied any symptoms. Patientscomplained of atypical symptoms, such as leg or back pain, tingling sensation in the leg, and difficulty breathing or chesttightness, as well as typical orthostatic symptoms. The BP decrease and the HR increase during the HUT test were greaterin the symptomatic group. A prolonged pressure recovery time during VM, a lower sweat output during QSART, and ahigher composite autonomic severity score were observed in the symptomatic group. Conclusions: Approximately one-fifth of the patients complained of symptoms during the HUT test, and thosesymptoms were strongly correlated with the autonomic parameters suggestive of impaired compensative mechanismsin response to a BP fall.
Abstract
Background: The aims of the present study were to identify the orthostatic symptoms occurring during the head-up tilt(HUT) test and to compare the autonomic parameters in patients with and without symptoms during the HUT test. Methods: We retrospectively collected autonomic data from patients presenting with autonomic symptoms includingorthostatic dizziness over a 1-year period. A standardized battery of autonomic tests was performed, including the HUTtest, Valsalva maneuver (VM), heart rate (HR) deep breathing test, and quantitative sudomotor axon reflex test (QSART)using Finometer devices to record the beat-to-beat blood pressure (BP) and HR response. We also investigated thepatients’ symptoms during the HUT test and compared the autonomic parameters between patients with and withoutorthostatic symptoms. Results: In total, 898 patients who submitted to autonomic function tests were included in this study. Of these, 17%(157/898) complained of various kinds of symptoms during tilting, while the remainder denied any symptoms. Patientscomplained of atypical symptoms, such as leg or back pain, tingling sensation in the leg, and difficulty breathing or chesttightness, as well as typical orthostatic symptoms. The BP decrease and the HR increase during the HUT test were greaterin the symptomatic group. A prolonged pressure recovery time during VM, a lower sweat output during QSART, and ahigher composite autonomic severity score were observed in the symptomatic group. Conclusions: Approximately one-fifth of the patients complained of symptoms during the HUT test, and thosesymptoms were strongly correlated with the autonomic parameters suggestive of impaired compensative mechanismsin response to a BP fall.
참고문헌 (13)
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