건강한 한국인의 발한반응에 대한 성별 및 연령의 영향; 예비조사연구
The Gender and Age Effect on the Sweat Response in Korean Healthy Subjects; A Preliminary Study
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Objectives: Quantitative sudomotor axon reflex test (QSART) measuring activity of postganglionic and sympathetic sudomotor fibers is widely used as a sensitive test for autonomic dysfunction. However, its normal values are not established in Korean population yet. Therefore the aim of this study is to establish normal values for QSART, and to investigate the gender and age effect on its value. Methods: Thirty-three healthy volunteers (15 women, 18 men) aged 20-69 years were recruited. QSART were measured at medial forearm, lateral proximal calf, and distal medial leg by using QSWEATTM (WR Medical Electronics Co., Minnesota, USA). Results: The mean volumes of sweat responses on forearm, proximal calf, and distal leg were 0.34±0.37 ㎕/cm2, 0.61±0.51 ㎕/cm2, 0.70±0.42 ㎕/cm2 in women, and 0.79±0.81 ㎕/cm2, 1.53±1.52 ㎕/cm2, 1.73 ±1.17 ㎕/cm2 in men, respectively showing women had less than one half of the sweat volumes of men. There were no significant differences in the mean volumes measured at according to age (p>0.05). However the ratio of sweat volume on proximal leg relative to distal leg significantly increased with age (p=0.044). Conclusion: This study shows that the sweat response of women is less than half of men. However sweat response is comparable according to age. More recruitment of healthy population is needed to generalize the study results.
Abstract
Objectives: Quantitative sudomotor axon reflex test (QSART) measuring activity of postganglionic and sympathetic sudomotor fibers is widely used as a sensitive test for autonomic dysfunction. However, its normal values are not established in Korean population yet. Therefore the aim of this study is to establish normal values for QSART, and to investigate the gender and age effect on its value. Methods: Thirty-three healthy volunteers (15 women, 18 men) aged 20-69 years were recruited. QSART were measured at medial forearm, lateral proximal calf, and distal medial leg by using QSWEATTM (WR Medical Electronics Co., Minnesota, USA). Results: The mean volumes of sweat responses on forearm, proximal calf, and distal leg were 0.34±0.37 ㎕/cm2, 0.61±0.51 ㎕/cm2, 0.70±0.42 ㎕/cm2 in women, and 0.79±0.81 ㎕/cm2, 1.53±1.52 ㎕/cm2, 1.73 ±1.17 ㎕/cm2 in men, respectively showing women had less than one half of the sweat volumes of men. There were no significant differences in the mean volumes measured at according to age (p>0.05). However the ratio of sweat volume on proximal leg relative to distal leg significantly increased with age (p=0.044). Conclusion: This study shows that the sweat response of women is less than half of men. However sweat response is comparable according to age. More recruitment of healthy population is needed to generalize the study results.
참고문헌 (11)
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