Voiding Dysfunction after Total Mesorectal Excision in Rectal Cancer
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Purpose: The aim of this study was to assess the voiding dysfunction after rectal cancer surgery with total mesorectal excision (TME). Methods: This was part of a prospective study done in the rectal cancer patients who underwent surgery with TME between November 2006 and June 2008. Consecutive uroflowmetry, post-voided residual volume, and a voiding questionnaire were per¬formed at preoperatively and postoperatively. Results: A total of 50 patients were recruited in this study, including 28 male and 22 female. In the comparison of the preopera¬tive data with the postoperative 3-month data, a significant decrease in mean maximal flow rate, voided volume, and post-voided residual volume were found. In the comparison with the postoperative 6-month data, however only the maximal flow rate was decreased with statistical significance (P=0.02). In the comparison between surgical methods, abdominoperineal resection pa¬tients showed delayed recovery of maximal flow rate, voided volume, and post-voided residual volume. There was no significant difference in uroflowmetry parameters with advances in rectal cancer stage. Conclusions: Voiding dysfunction is common after rectal cancer surgery but can be recovered in 6 months after surgery or ear¬lier. Abdominoperineal resection was shown to be an unfavorable factor for postoperative voiding. Larger prospective study is needed to determine the long-term effect of rectal cancer surgery in relation to male and female baseline voiding condition.
Abstract
Purpose: The aim of this study was to assess the voiding dysfunction after rectal cancer surgery with total mesorectal excision (TME). Methods: This was part of a prospective study done in the rectal cancer patients who underwent surgery with TME between November 2006 and June 2008. Consecutive uroflowmetry, post-voided residual volume, and a voiding questionnaire were per¬formed at preoperatively and postoperatively. Results: A total of 50 patients were recruited in this study, including 28 male and 22 female. In the comparison of the preopera¬tive data with the postoperative 3-month data, a significant decrease in mean maximal flow rate, voided volume, and post-voided residual volume were found. In the comparison with the postoperative 6-month data, however only the maximal flow rate was decreased with statistical significance (P=0.02). In the comparison between surgical methods, abdominoperineal resection pa¬tients showed delayed recovery of maximal flow rate, voided volume, and post-voided residual volume. There was no significant difference in uroflowmetry parameters with advances in rectal cancer stage. Conclusions: Voiding dysfunction is common after rectal cancer surgery but can be recovered in 6 months after surgery or ear¬lier. Abdominoperineal resection was shown to be an unfavorable factor for postoperative voiding. Larger prospective study is needed to determine the long-term effect of rectal cancer surgery in relation to male and female baseline voiding condition.
참고문헌 (27)
- Jemal A, "Cancer statistics, 2010", CA Cancer J Clin, 60, pp.277~300 (2010)
- Heald RJ, , Lancet, 1, pp.1479~1482 (1986)
- Kapiteijn E, "Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer", N Engl J Med, 345, pp.638~646 (2001)
- Desnoo L, "A qualitative study of anterior resection syndrome: the experiences of cancer survivors who have undergone resection surgery", Eur J Cancer Care, 15, pp.244~251 (2006)
- Vironen JH, "Impact of functional results on quality of life after rectal cancer surgery", Dis Colon Rectum, 49, pp.568~578 (2006)
- Moreira ED Jr, "GSSAB Investigators Group. A population survey of sexual activity, sexual dysfunction and associated help-seeking behavior in middle-aged and older adults in Germany", Eur J Med Res, 10, pp.434~443 (2005)
- Smith LJ, "Sex after seventy: a pilot study of sexual function in older persons", J Sex Med, 4, pp.1247~1253 (2007)
- Junginger T, "Influence of identification and preservation of pelvic autonomic nerves in rectal cancer surgery on bladder dysfunction after total mesorectal excision", Dis Colon Rectum, 46, pp.621~628 (2003)
- Moriya Y, "Function preservation in rectal cancer surgery", Int J Clin Oncol, 11, pp.339~343 (2006)
- Lange MM, "Urinary dysfunction after rectal cancer treatment is mainly caused by surgery", Br J Surg, 95, pp.1020~1028 (2008)
- Havenga K, "Male and female sexual and urinary function after total mesorectal excision with autonomic nerve preservation for carcinoma of the rectum", J Am Coll Surg, 182, pp.495~502 (1996)
- Heald RJ, "Rectal cancer: the Basingstoke experience of total mesorectal excision, 1978-1997", Arch Surg, 133, pp.894~899 (1998)
- Heald RJ, "A new approach to rectal cancer", Br J Hosp Med, 22, pp.277~281 (1979)
- Mynster T, "Danish TME-group, RANX05-group. Blood loss and transfusion after total mesorectal excision and conventional rectal cancer surgery", Colorectal Dis, 6, pp.452~457 (2004)
- Enker WE, "Potency, cure, and local control in the operative treatment of rectal cancer", Arch Surg, 127, pp.1396~1401 (1992)
- Marijnen CA, "Impact of short-term preoperative radiotherapy on health-related quality of life and sexual functioning in primary rectal cancer: report of a multicenter randomized trial", J Clin Oncol, 23, pp.1847~1858 (2005)
- Sterk P, "Voiding and sexual dysfunction after deep rectal resection and total mesorectal excision: prospective study on 52 patients", Int J Colorectal Dis, 20, pp.423~427 (2005)
- Kneist W, "Major urinary dysfunction after mesorectal excision for rectal carcinoma", Br J Surg, 92, pp.230~234 (2005)
- Benoist S, "Optimal duration of urinary drainage after rectal resection: a randomized controlled trial", Surgery, 125, pp.135~141 (1999)
- Nesbakken A, "Bladder and sexual dysfunction after mesorectal excision for rectal cancer", Br J Surg, 87, pp.206~210 (2000)
- Lange MM, "Urinary and sexual dysfunction after rectal cancer treatment", Nat Rev Urol, 8, pp.51~57 (2011)
- Wallner C, "Causes of fecal and urinary incontinence after total mesorectal excision for rectal cancer based on cadaveric surgery: a study from the Cooperative Clinical Investigators of the Dutch total mesorectal excision trial", J Clin Oncol, 26, pp.4466~4472 (2008)
- Grigsby PW, "Late injury of cancer therapy on the female reproductive tract", Int J Radiat Oncol Biol Phys, 31, pp.1281~1299 (1995)
- Daniels IR, "Female urogenital dysfunction following total mesorectal excision for rectal cancer", World J Surg Oncol, 4, pp.6~ (2006)
- Herbison GP, "Sacral neuromodulation with implanted devices for urinary storage and voiding dysfunction in adults", Cochrane Database Syst Rev, (2), pp.CD004202~ (2009)
- Maas CP, "Radical and nerve-preserving surgery for rectal cancer in The Netherlands: a prospective study on morbidity and functional outcome", Br J Surg, 85, pp.92~97 (1998)
- Maurer CA, "Total mesorectal excision preserves male genital function compared with conventional rectal cancer surgery", Br J Surg, 88, pp.1501~1505 (2001)