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短期間의 韭子 投與가 생쥐의 筋疲勞와 筋力에 미치는 影響

Short term effect of Allii tuberosi semen on muscular fatigue and muscular strength

이진무|장준복|이창훈|조정훈|이경섭|변상현
대한한방부인과학회 (The Society Of Oriental Obstetrics & Gynecology)|2007.05|대한한방부인과학회지 (The Journal of Oriental Obstetrics ＆ Gynecology)|제20권 제2호|pp. 60-70

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키워드

glucosemiceAllii tuberosi semenmuscle fatigueswimming exercise testgrip strength testlactate dehydrogenase
주제분류한의학

초록

Purpose: This study was conducted to investigate the muscle anti-fatigue effects of Allii tuberosi semen after short term administration. Methods: 4-6 weeks old ICR mice were used in this study and we administered the water soluble extracts of Allii tuberosi semen in the concentration of 1, 10 and 100㎎/0.3㎖ to each 5 mice (ATS group) and same volume of normal saline was administered to 5 mice (control group) once a day for 30 or 60 days. After the administration we performed the swimming exercise test and the grip strength test. And we measured the concentration of glucose and the activity of lactate dehydrogenase in plasma regarded as biochemical indicator related with the muscular fatigue.. Results: In swimming exercise test, 10 and 100㎎/0.3㎖ ATS groups showed increased time compared with relative control group after 30 days administration. But after 60 days adminstration all ATS groups showed increased results. In grip strength test, 100㎎/0.3㎖ ATS group increased grip strength after 30 days administration and 10㎎/0.3㎖ ATS group showed increased result after 60 days administration. All the results of plasma glucose and lactate dehydrogenase didn't showed statistically significant difference after 30 and 60 days administration. Conclusion: From this study we could find the anti-fatigue effect of Allii tuberosi semen in the muscle strength related test.

Abstract

Purpose: This study was conducted to investigate the muscle anti-fatigue effects of Allii tuberosi semen after short term administration. Methods: 4-6 weeks old ICR mice were used in this study and we administered the water soluble extracts of Allii tuberosi semen in the concentration of 1, 10 and 100㎎/0.3㎖ to each 5 mice (ATS group) and same volume of normal saline was administered to 5 mice (control group) once a day for 30 or 60 days. After the administration we performed the swimming exercise test and the grip strength test. And we measured the concentration of glucose and the activity of lactate dehydrogenase in plasma regarded as biochemical indicator related with the muscular fatigue.. Results: In swimming exercise test, 10 and 100㎎/0.3㎖ ATS groups showed increased time compared with relative control group after 30 days administration. But after 60 days adminstration all ATS groups showed increased results. In grip strength test, 100㎎/0.3㎖ ATS group increased grip strength after 30 days administration and 10㎎/0.3㎖ ATS group showed increased result after 60 days administration. All the results of plasma glucose and lactate dehydrogenase didn't showed statistically significant difference after 30 and 60 days administration. Conclusion: From this study we could find the anti-fatigue effect of Allii tuberosi semen in the muscle strength related test.

참고문헌 (25)

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