생쥐의 筋疲勞 및 血液成分에 대한 短期 人蔘投與의 效果에 관한 硏究
A study on the short-term effects of Ginseng Radix Alba extract on muscle fatigue and blood components of the rats
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Purpose: This study was conducted to investigate the short-term effects of Ginseng Radix Alba extract solution on muscle fatigue and concentration of blood components especially in glucose and lactate dehydrogenase of the rats. Methods: The 4~6-week-old ICR rats are used in the study, and we administered the extract solution of Ginseng Radix Alba concentration of 1, 10, 100㎎/0.3㎖ to each rats and water to another rats(control group) once a day for each 30 and 60 days. After 30 and 60 days, we measured the persistent time of swimming exercise test and the results of grip strength test. And we also examined the plasma concentraion of glucose, and lactate dehydrogenase. Results: In swimming exercise test, the swimming time of the 1, 10, 100㎎/0.3㎖ groups for 30 days and the 100㎎/0.3㎖ group for 60 days significantly increased than control group. and we found that as the concentration increased, the swimming time was also increased for 30 and 60 days experiment. And in grip strength test, the grip strength of the 1, 10, 100㎎/0.3㎖ groups for 30 days and the 10㎎/0.3㎖ group for 60 days significantly increased than control group. and we found that as the concentration increased, the grip strength was also increased for 30 days experiment. Plasma concentration of lactate dehydrogenase was significantly increased in the 10㎎/0.3㎖ group for 60 days than control group. And there was no significant differences between the control and the treatment group in the plasma concentration of glucose. Conclusion: This study show that Ginseng Radix Alba can increase the muscle strength and antifatigue effect.
Abstract
Purpose: This study was conducted to investigate the short-term effects of Ginseng Radix Alba extract solution on muscle fatigue and concentration of blood components especially in glucose and lactate dehydrogenase of the rats. Methods: The 4~6-week-old ICR rats are used in the study, and we administered the extract solution of Ginseng Radix Alba concentration of 1, 10, 100㎎/0.3㎖ to each rats and water to another rats(control group) once a day for each 30 and 60 days. After 30 and 60 days, we measured the persistent time of swimming exercise test and the results of grip strength test. And we also examined the plasma concentraion of glucose, and lactate dehydrogenase. Results: In swimming exercise test, the swimming time of the 1, 10, 100㎎/0.3㎖ groups for 30 days and the 100㎎/0.3㎖ group for 60 days significantly increased than control group. and we found that as the concentration increased, the swimming time was also increased for 30 and 60 days experiment. And in grip strength test, the grip strength of the 1, 10, 100㎎/0.3㎖ groups for 30 days and the 10㎎/0.3㎖ group for 60 days significantly increased than control group. and we found that as the concentration increased, the grip strength was also increased for 30 days experiment. Plasma concentration of lactate dehydrogenase was significantly increased in the 10㎎/0.3㎖ group for 60 days than control group. And there was no significant differences between the control and the treatment group in the plasma concentration of glucose. Conclusion: This study show that Ginseng Radix Alba can increase the muscle strength and antifatigue effect.
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