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한국 성인의 비타민 D와 치주질환의 관계

Association of Periodontitis with Serum Vitamin D Level among Korean Adults

황희진|김재민
한국치위생과학회 (The Korean Society of Dental Hygiene Science)|2018.08|치위생과학회지 (Journal of Dental Hygiene Science)|제18권 제4호|pp. 210-217|DOI 10.17135/jdhs.2018.18.4.210

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AdultVitamin DPeriodontal diseases
주제분류치의학

초록

치주질환은 광범위한 만성 염증질환으로 삶의 질, 영양섭취에 큰 영향을 준다. 몇몇의 연구에서 치주질환과 골밀도가 낮은 사람과의 연관성이 보고되고 있으며 비타민 D는골밀도뿐 아니라 항염증효과도 있기 때문에 치주질환에도 좋은 영향을 줄 것으로 예측된다. 하지만 연구에 따라 다른결과를 보이고 한국에서는 이에 대한 연구가 부족하므로, 한국인에서 비타민 D와 치주질환의 관계를 알아보기 위하여 본 연구를 시행하였다. 본 연구는 대한민국에서 실시한국민건강영양조사 2012∼2014년의 3개년도 23,626명 중20세 이상, 비타민 D 혈중농도, 치주질환의 유무가 있는8,783명을 대상으로 다중선형회귀분석을 시행하여 연령별, 성별 비타민 D 혈중농도와 치주질환이 관계가 있는지 살펴보았다. 치아 상실과 비타민 D의 농도는 음의 상관관계를가졌다(=−0.028, p=0.008). 또한 대상군 중 50세 이하의남성에서 비타민 D의 농도가 낮을수록 치주질환의 유병률이 높은 것으로 나타났다(Q1: 1.769 [1.125∼2.782], Q2: 1.182 [0.743∼1.881], Q3: 0.676 [0.400∼1.881]; p=0.001). 비타민 D의 결핍과 치주질환은 진료현장에서 흔히 볼 수 있는 질환이다. 비타민 D의 보충으로 치주질환 및 낙상, 골다공증, 골관절염, 암 등에서 좋은 영향을 미칠 것으로 기대되므로 치주질환이 있는 환자에게는 치주질환의 관리뿐만 아니라 삶의 질 향상을 위해 비타민 D 농도의 일정수준 유지가 도움이 될 수 있겠다. 따라서 본 연구에서와 같이 노인뿐만 아니라 50세 이하 성인남성에서도 연관이 있으므로, 성인에서도 비타민 D 농도의 일정수준 유지에 관심을 가져야할 것이다.

Abstract

Periodontal disease is a chronic inflammatory disease that affects quality of life and nutrition. Several studies have demonstrated a link between periodontal disease and low bone density, and vitamin D is expected to have a beneficial effect on periodontal disease as well as on bone mineral density and anti-inflammatory effects. The purpose of this study was to identify the association between periodontal disease and vitamin D because the results are different in some studies and there is a lack of research in Korea. In this study, we conducted a multiple linear regression analysis of 8,783 subjects among 23,626 subjects who were older than 20 years of age, who had serum vitamin D levels and periodontal disease, who had three years of the National Health and Nutrition Survey that was conducted in Korea from 2012 to 2014. We examined the relationship between serum vitamin D levels and periodontal disease. Tooth loss and vitamin D levels were negatively correlated (=−0.028, p=0.008). In addition, the prevalence of periodontal disease was found to be higher in men younger than 50 years of age with lower vitamin D levels (Q1: 1.769 [1.125∼ 2.782], Q2: 1.182 [0.743∼1.881], Q3: 0.676 [0.400∼1.881]; p=0.001). Low vitamin D levels and periodontal disease are common diseases in primary care. Vitamin D supplementation is expected to have favorable effect on periodontal disease and falls, osteoporosis, osteoarthritis, and cancer. Therefore, patients with periodontal disease may benefit from periodic vitamin D management to improve quality of life as well as to manage periodontal disease. In addition, as shown in this study, not only elderly individuals, but also men younger than 50 years of age are related to periodontal disease, so there should be interest in controlling the levels of vitamin D in adults.

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관련 논문AI추천

Low serum 25-hydroxyvitamin D levels, tooth loss, and the prevalence of severe periodontitis in Koreans aged 50 years and older권순석, 김영준, 김옥수, 김옥준, 김현주, 신민호, 윤숙자, 이영훈, 정현주, 최창균대한치주과학회 · Journal of Periodontal & Implant Science2020 · 제50권 제6호Association between Vitamin D Level in Blood and Periodontitis in Korean Elderly유병철, 윤나나, 이지영한국치위생과학회 · 치위생과학회지2017 · 제17권 제3호50세 이상 폐경여성의 혈중 비타민 D 농도와 치면세마필요자율의 관련성노상철, 이선희한국치위생과학회 · 치위생과학회지2013 · 제13권 제4호An Association between Vitamin Intakes and Established Periodontitis in Korean Adult Population정성화, 천세희한국치위생과학회 · 치위생과학회지2014 · 제14권 제4호치주질환 유무에 따른 건강행태와 영양상태김창희, 이선미, 이춘선한국치위생학회 · 한국치위생학회지2021 · 제21권 제5호The Association Between Vitamins A, E and Periodontal Disease: Using the 7th National Health and Nutrition Survey Data (2016-2018)김재현, 김지량, 장종화융합연구학회 · The Journal of Transdisciplinary Studies2022 · 제6권 제3호

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