Effect of Castor Oil on Cervical Ripening and Labor Induction: a systematic review and meta-analysis
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Objectives: Post-term pregnancy is a condition associated with increased maternal and fetal complications. Administration of castor oil causes cervical stimulation by increasing the production of prostaglandins. We examined the effects of castor oil on cervical ripening and labor induction through a systematic review and meta-analysis. Methods: The search process was performed to obtain relevant articles from databases including Pubmed, Cochrane library, Scopus, Science direct, SID, Iran Medex, and Google Scholar using the English keywords of cervical ripening, post-term, castor oil, labor induction, Bishop score, and pregnancy considering all possible combinations without time constraints and their Persian equivalents from national databases. Results: A total of eight related articles from the 19 primary studies were extracted and systematically reviewed. According to a cumulative chart, the difference in the post-intervention Bishop score was statistically significant (standard mean difference [SMD]: 1.64, 95% confidence interval [CI]: 1.67-2.11, p = 0.001), indicating an effect of castor oil on increasing the Bishop score. In addition, the difference in labor induction was statistically significant after the intervention (odds ratio: 11.67, 95% CI: 3.34-40.81, p = 0.001), indicating an effect of castor oil on increasing the odds ratio of labor induction (experience of vaginal delivery). Conclusion: This meta-analysis showed that oral administration of castor oil is effective for cervical ripening and labor induction. Midwives should closely monitor pregnant women with prolonged labor and collaborate with obstetricians to employ castor oil as a safe intervention to induce cervical ripening and labor to prevent undue caesarean surgery.
Abstract
Objectives: Post-term pregnancy is a condition associated with increased maternal and fetal complications. Administration of castor oil causes cervical stimulation by increasing the production of prostaglandins. We examined the effects of castor oil on cervical ripening and labor induction through a systematic review and meta-analysis. Methods: The search process was performed to obtain relevant articles from databases including Pubmed, Cochrane library, Scopus, Science direct, SID, Iran Medex, and Google Scholar using the English keywords of cervical ripening, post-term, castor oil, labor induction, Bishop score, and pregnancy considering all possible combinations without time constraints and their Persian equivalents from national databases. Results: A total of eight related articles from the 19 primary studies were extracted and systematically reviewed. According to a cumulative chart, the difference in the post-intervention Bishop score was statistically significant (standard mean difference [SMD]: 1.64, 95% confidence interval [CI]: 1.67-2.11, p = 0.001), indicating an effect of castor oil on increasing the Bishop score. In addition, the difference in labor induction was statistically significant after the intervention (odds ratio: 11.67, 95% CI: 3.34-40.81, p = 0.001), indicating an effect of castor oil on increasing the odds ratio of labor induction (experience of vaginal delivery). Conclusion: This meta-analysis showed that oral administration of castor oil is effective for cervical ripening and labor induction. Midwives should closely monitor pregnant women with prolonged labor and collaborate with obstetricians to employ castor oil as a safe intervention to induce cervical ripening and labor to prevent undue caesarean surgery.
참고문헌 (38)
- Cunningham FG, "Williams obstetrics", pp.1344~ (2018), McGraw Hill
- Mollart LJ, "Acupressure for post-date pregnancy: a sequential mixed-methods feasibility study", pp.2018
- Mya KS, "Management of pregnancy at and beyond 41completed weeks of gestation in low-risk women : a secondary analysis of two WHO multi-country surveys on maternal and newborn health", Reprod Health, 14(1), pp.141~ (2017)
- Gibbs RS, "Danforth’s obstetrics and gynecology" (2008), Lippincott Williams & Wilkins
- Kawakita T, "Predicting vaginal delivery in nulliparous women undergoing induction of labor at term", Am J Perinatol, 35(7), pp.660~668 (2018)
- Tan TC, "A randomised controlled trial of low-dose misoprostol and dinoprostone vaginal pessaries for cervical priming", BJOG, 117, pp.1270~1277 (2010)
- Guerra GV, "Factors and outcomes associated with the induction of labour in Latin America", BJOG, 116(13), pp.1762~1772 (2009)
- Al-Shaikh GK, "Factors associated with successful induction of labor", Saudi Med J, 33(3), pp.298~303 (2012)
- PonMalar J, "Randomized double-blind placebo controlled study of preinduction cervical priming with 25 μg of misoprostol in the outpatient setting to prevent formal induction of labour", Arch Gynecol Obstet, 295(1), pp.33~38 (2017)
- Teixeira C, "The Bishop Score as a determinant of labour induction success : a systematic review and meta-analysis", Arch Gynecol Obstet, 286(3), pp.739~753 (2012)
- Gilstrop M, "Induction of labor--pharmacology methods", Semin Perinatol, 39(6), pp.463~465 (2015)
- "Obstet Gynecol", 2016, 104S~105S
- 신현주, "Anaphylactic shock to vaginal misoprostol: a rare adverse reaction to a frequently used drug", Obstetrics & Gynecology Science, 61(5), pp.636~640 (2018), 대한산부인과학회[DOI]
- Thorbiörnson A, "Oral versus vaginal prostaglandin for labor induction", J Matern Fetal Neonatal Med, 30(7), pp.789~792 (2017)
- Ghasemi V, "Effective interventions for the induction of labor : a systematic review", Iran J Obstet Gynecol Infertil, 21(1), pp.90~104 (2018)
- Tunaru S, "Castor oil induces laxation and uterus contraction via ricinoleic acid activating prostaglandin EP3 receptors", Proc Natl Acad Sci U S A, 109(23), pp.9179~9184 (2012)
- Gilad R, "Castor oil for induction of labor in post-date pregnancies : a randomized controlled trial", Women Birth, 31(1), pp.e26~e31 (2018)
- Boel ME, "Castor oil for induction of labor : not harmful, not helpful", Obstet Gynecol Surv, 65(2), pp.77~78 (2010)
- Okoro OS, "Effectiveness of castor oil in preventing post-term pregnancy in low resource setting : a randomized controlled trial", Am J Clin Med Res, 7(2), pp.37~43 (2019)
- Kelly AJ, "Castor oil, bath and", or enema for cervical priming and induction of labour, 2013, pp.2013(7), CD003099~
- Neri I, "Castor oil for induction of labour : a retrospective study", J Matern Fetal Neonatal Med, 31(16), pp.2105~2108 (2018)
- Asar S, "PRISMA;preferred reporting items for systematic reviews and metaanalyses", J Rafsanjan Univ Med Sci, 15(1), pp.68~80 (2016)
- Higgins JP, "The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials", BMJ, 343, pp.d5928~ (2011)
- DeMaria AL, "Castor oil as a natural alternative to labor induction : a retrospective descriptive study", Women Birth, 31(2), pp.e99~e104 (2018)
- Sultana A, "Usefulness of polyherbal Unani formulation for cervical ripening and induction of labour : a uncontrolled study", Altern Integ Med, 4(1), pp.1000184~ (2015)
- Hall HG, "Complementary and alternative medicine for induction of labour", Women Birth, 25(3), pp.142~148 (2012)
- Boltman-Binkowski H, "A systematic review: are herbal and homeopathic remedies used during pregnancy safe?", Curationis, 39(1), pp.1514~ (2016)
- Lamadah SM, "Castor oil safety and effectiveness on labour induction and neonatal outcome", J Biol Agric Healthc, 4(4), pp.1~10 (2014)
- Kahnamoyiagdam F, "The effect of castor oil on the induction of labor : a clinical trial", Nurs Midwifery J, 12(5), pp.348~353 (2014)
- Azarkish F, "Effect of oral castor oil on labor pain in post term pregnancy", Sci J Kurd Univ Med Sci, 13(3), pp.1~6 (2008)
- Iravani M, "A study on the safety and efficacy of castor oil for cervical ripening and labour induction", Jundishapur Sci Med J, 5(1), pp.398~404 (2006)
- Saberi F, "Effect of castor oil on induction of labor", J Kashan Univ Med Sci, 11(4), pp.19~23 (2008)
- Saberi F, "The use of castor oil on cervical ripening in pregnancies", J Mazandaran Univ Med Sci, 18(63), pp.11~19 (2008)
- Azhari S, "Evaluation of the effect of castor oil on initiating labor in term pregnancy", Saudi Med J, 27(7), pp.1011~1014 (2006)
- Conceição M, "Evaluation of the oxidative induction time of the ethilic castor biodiesel", J Therm Anal Calorim, 97(2), pp.643~646 (2009)
- Sicuranza GB, "Uterine rupture associated with castor oil ingestion", J Matern Fetal Neonatal Med, 13(2), pp.133~134 (2003)
- Grove SK, "Understanding nursing research: building an evidence-based practice, First South Asia Edition" (2019), Elsevier India
- Zamawe C, "Effectiveness and safety of herbal medicines for induction of labour : a systematic review and meta-analysis", BMJ Open, 8(10), pp.e022499~ (2018)
