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산후 오로부절 및 자궁 복구 불완전에 대한 생화탕(生化湯) 치료의 효과 : 체계적 문헌고찰과 메타분석

Saenghwa-tang Treatment on Postpartum Prolonged Lochia and Uterine Subinvolution: a Systematic Review and Meta-Analysis

김동철|송지윤
대한한방부인과학회 (The Society Of Oriental Obstetrics & Gynecology)|2023.11|대한한방부인과학회지 (The Journal of Oriental Obstetrics ＆ Gynecology)|제36권 제4호|pp. 121-139|DOI https://doi.org/10.15204/jkobgy.2023.36.4.121

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참고문헌

키워드

Systematic ReviewHerbal MedicineProlonged LochiaPostpartum Uterine SubinvolutionSaenghwa-tang
주제분류한의학

초록

Objectives: This study was performed to analyze randomized controlled trial, which studied the effect of Saenghwa-tang treatment on postpartum prolonged lochia and uterine subinvolution. Methods: Researchers searched for randomized controlled trial of based on postpartum prolonged lochia, uterine subinvolution and Saenghwa-tang. The paper search was conducted through 6 online databases on August 10, 2023. Results: 8 studies were included after selection and exclusion criteria. 5 studies compared Saenghwa-tang alone with western medicine. 3 studies compared combined treatment of Saenghwa-tang and western medicine, with western medicine alone. Comparing with control group, the treatment group showed statistically significant improvement on total effective rate, uterine involution, serum fibrinogen, D-dimer, viscosity of blood and plasma, Erythrocyte aggregation, and various symptoms. Conclusions: This study suggests that Saenghwa-tang has benefit for treating prolonged lochia and uterine subinvolution. For reliable evidence, further research is needed to establish safety of Saenghwa-tang, standardize diagnosis criteria and specify the treatment course.

Abstract

Objectives: This study was performed to analyze randomized controlled trial, which studied the effect of Saenghwa-tang treatment on postpartum prolonged lochia and uterine subinvolution. Methods: Researchers searched for randomized controlled trial of based on postpartum prolonged lochia, uterine subinvolution and Saenghwa-tang. The paper search was conducted through 6 online databases on August 10, 2023. Results: 8 studies were included after selection and exclusion criteria. 5 studies compared Saenghwa-tang alone with western medicine. 3 studies compared combined treatment of Saenghwa-tang and western medicine, with western medicine alone. Comparing with control group, the treatment group showed statistically significant improvement on total effective rate, uterine involution, serum fibrinogen, D-dimer, viscosity of blood and plasma, Erythrocyte aggregation, and various symptoms. Conclusions: This study suggests that Saenghwa-tang has benefit for treating prolonged lochia and uterine subinvolution. For reliable evidence, further research is needed to establish safety of Saenghwa-tang, standardize diagnosis criteria and specify the treatment course.

참고문헌 (38)

  1. The Society of Korean Medicine Obstetrics and Gynecology, "Korean Medicine Obstetrics & Gynecology (Vol. 2)", pp.718~719 (2016), Euiseongdang Publishing Co
  2. LI X, "Clinical study on patterns of postpartum lochia", Chinese Journal of Perinatal Medicin, 8(6), pp.372~374 (2005)
  3. Oppenheimer LW, "The duration of lochia", BJOG, 93(7), pp.754~757 (1986)
  4. Zhang ZJ, "Zhong jing quan shu(仲景全書)", pp.431~ (1984), Daesung Cultural History
  5. 김동일, "《婦人大全良方》에 관한 연구", 대한한방부인과학회지, 15(4), pp.76~97 (2002), 대한한방부인과학회
  6. Fu S, "Buchungjunamyeogwa subcheonsayeogwa(傅靑主男女科葉士女科)", pp.145~148 (1984), Daesung Cultural History
  7. Ye TS, "Ye Tianshi's Gynecology(葉天士女科)", pp.305~307 (1992), Daesung Cultural History
  8. 김평화, "산후기에 활용된 한약처방에 대한 국내 연구 분석", 대한한방부인과학회지, 31(4), pp.128~146 (2018), 대한한방부인과학회[DOI]
  9. Korean Society of Obstetrics and Gynecology, "Obstetrics", pp.494~ (2019), Koonja publishing house
  10. Luo J, "Analysis on Medication Rules of Chinese Medicinal Herb Formulae in Uterine Subinvolution Treatment Based on Data Mining", Evid Based Complement Alternat Med, 2022, pp.1752352~ (2022)
  11. Huang SS, "Herbs for lochia discharge used among postpartum women in Taiwan", J Ethnopharmacol, 313, pp.116552~ (2023)
  12. Malik M, "Pharmacological chaperones for the oxytocin receptor increase oxytocin responsiveness in myometrial cells", J Biol Chem, 298(3), pp.101646~ (2022)
  13. 조승희, "한방병원 부속 산후조리원을 이용한 산모의 산후 오로 기간과 특징에 관한 고찰", 대한한방부인과학회지, 26(3), pp.59~72 (2013), 대한한방부인과학회
  14. Kim DI, "Case Report : Treatment of Persistent Bloody Lochia With Talhwajungagambang", J Korean Obestet Gynecol, 12(1), pp.323~330 (1999)
  15. 안수정, "流産後 惡露不止 患者 治驗 1例", 대한한방부인과학회지, 17(3), pp.223~232 (2004), 대한한방부인과학회
  16. Kim SW, "Clinical Study of Gamisaenghwa-tang in Treatment of Woman with Caesarian Section", The Journal of Kyung Hee University, 14(2), pp.191~203 (1998)
  17. 박성혜, "전통 산후 회복식과 한방 생화탕이 산모의 회복 정도에 미치는 효과", 한국식품영양과학회지, 34(5), pp.652~658 (2005), 한국식품영양과학회
  18. 김동환, "木香生化湯과 木香生化湯加鹿茸이 産後回復및 乳汁分泌에 미치는 影響", 대한한방부인과학회지, 18(1), pp.111~127 (2005), 대한한방부인과학회
  19. Wang Y, "Clinical observation of Saenghwa-tang-gagam treatment on 56 cases of postpartum uterine subinvolution(生化汤加减治疗产后子宫复旧不良56例疗效观察)", Guiding Journal of Traditional Chinese Medicine and Pharmacy, 15(4), pp.43~44 (2009)
  20. Liu FB, "Clinical observation of Gagamsaenghwa-tang treatment on postpartum prolonged lochia(加减生化汤治疗产后恶露不绝临床疗效观察)", Journal of Hubei University of Chinese Medicine, 13(4), pp.54~55 (2011)
  21. Peng MZ, "Clinical observation of Saenghwa-tang-gagam treatment on 60 cases of postpartum prolonged lochia(生化汤加减治疗产后恶露不绝60例临床疗效观察)", Asia-Pacific Traditional Medicine, 11(13), pp.133~134 (2015)
  22. Niu RF, "Clinical observation of Saenghwa-tang-gami combined with ocytocin treatment on postpartum uterine subinvolution(生化汤加味联合缩宫素治疗产后子宫复旧不良临床观察)", Journal of New Chinese Medicine, 48(9), pp.1035~ (2016)
  23. Liang YF, "Clinical observation of jiajian Shenghua decoction in treating postpartum lochiorrhea", China's Naturopathy, 28(09), pp.60~61 (2020)
  24. Zeng QX, "Clinical analysis of Saenghwa-tang treatment on postpartum prolonged lochia(生化汤治疗产后恶露不绝的疗效分析)", Shenzhen Journal of Integrated Traditional Chinese and Western Medicine, 31(10), pp.69~70 (2021)
  25. Chen ZY, "Clinical observation of Saenghwa-tang-gagam treatment on postpartum prolonged lochia(生化汤加减治疗产后恶露不绝临床观察)", Journal of Practical Traditional Chinese Medicine, 39(03), pp.467~469 (2023)
  26. Xue ZQ, "Clinical Observation on Shenghua Decoction Combined with Western Medicine in Treating Postpartum Lochia and Blood Stasis Syndrome", Guangming Journal of Chinese Medicine, 38(12), pp.2361~2363 (2023)
  27. Burton J, "When Your Patient Is Postpartum : Are You Confident in Your Skills?", Am J Nurs, 99(2), pp.64~70 (1999)
  28. Kim A, "Management of Postpartum Hemorrhage", J Korean Med Assoc, 50(12), pp.1096~1106 (2007)
  29. American College of Obstetricians Gynecologists, "ACOG Practice Bulletin : Clinical Management Guidelines for Obstetrician-Gynecologists Number 76, October 2006 : postpartum hemorrhage", Obstet Gynecol, 108(4), pp.1039~1047 (2006)
  30. Williams MJ, "Different classes of antibiotics given to women routinely for preventing infection at caesarean section", Cochrane Database Syst Rev, 3(3), pp.CD008726~ (2021)
  31. Chi C, "Puerperal loss(lochia)in women with or without inherited bleeding disorders", Am J Obstet Gynecol, 203(1), pp.56.e1~56.e5 (2010)
  32. Fletcher S, "Lochia patterns among normal women : a systematic review", J Womens Health, 21(12), pp.1290~1294 (2012)
  33. 이병권, "헌혈이 헌혈자의 혈유변학적 지표에 미치는 영향", 대한수혈학회지, 29(3), pp.229~239 (2018), 대한수혈학회[DOI]
  34. Hahn JS, "A Study on the Blood Viscosity in Healthy Control and Hematologic Diseases", Korean J Hematol, 25(2), pp.397~411 (1990)
  35. Lee TK, "A study of SaingHwa-Tang in Bucheungjueukwa", J Korean Obestet Gynecol, 12(2), pp.327~348 (1999)
  36. Li JM, "Regulation effect and mechanism of Sheng-Hua-Tang on female reproductive system : From experimental transcriptomic analysis to clinical applications", J Ethnopharmacol, 249, pp.112431~ (2020)
  37. Wang X, "Pharmacological mechanism of Shenghua Decoction in treatment of abdominal pain based on network pharmacology", Zhongguo Zhong Yao Za Zhi, 44(10), pp.2124~2130 (2019)
  38. Park KY, "Effects of Herbal Medicine on Breastfeeding-Analysis of Marker Substances in Saenghwatang by HPLC and LC", MS, J Korean Obestet Gynecol, pp.2013, 26(4)[DOI]

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