Meningovascular and Spinal form of Neurosyphilis Presenting as Multiple Cranial Nerve Palsy, Cerebral Infarction and Meningomyelitis in a Human Immunodeficiency Virus Negative-Patient: MR Imaging Features
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Neurosyphilis is a rare infection of the brain and spinal cord caused by a spirochete named Treponema pallidum. Wedescribe the magnetic resonance imaging of a 53-year-old man with syphilis who manifested as both meningovascular,and spinal meningomyelitic types, which involved the optic, trigeminal, facial and vestibulocochlear nerves, both middleand left posterior cerebral arteries, thoracic spinal cord and meninges of the lumbar spine. This case report suggests thatneurosyphilis should be considered as a possible diagnosis in patients showing complex brain and spinal imaging features. These features include enhancing meningeal lesions with multiple cranial nerve involvement, stenoses in large to mediumsize cerebral arteries, and intramedullary and meningeal lesions of spine.
Abstract
Neurosyphilis is a rare infection of the brain and spinal cord caused by a spirochete named Treponema pallidum. Wedescribe the magnetic resonance imaging of a 53-year-old man with syphilis who manifested as both meningovascular,and spinal meningomyelitic types, which involved the optic, trigeminal, facial and vestibulocochlear nerves, both middleand left posterior cerebral arteries, thoracic spinal cord and meninges of the lumbar spine. This case report suggests thatneurosyphilis should be considered as a possible diagnosis in patients showing complex brain and spinal imaging features. These features include enhancing meningeal lesions with multiple cranial nerve involvement, stenoses in large to mediumsize cerebral arteries, and intramedullary and meningeal lesions of spine.
참고문헌 (11)
- Tien RD, "Neurosyphilis in HIV carriers: MR findings in six patients", AJR Am J Roentgenol, 158, pp.1325~1328 (1992)
- Holland BA, "Meningovascular syphilis:CT and MR findings", Radiology, 158, pp.439~442 (1986)
- Wharton M, "Case definitions for public health surveillance", MMWR Recomm Resp, 39, pp.1~43 (1990)
- 윤영경, "Cerebral Syphilitic Gumma Mimicking a Brain Tumor in the Relapse of Secondary Syphilis in a Human Immunodeficiency Virus-Negative Patient", 대한신경외과학회지, 53(3), pp.197~200 (2013), 대한신경외과학회[DOI]
- Chilver-Stainer L, "Syphilitic myelitis: rare, nonspecific, but treatable", Neurology, 72, pp.673~675 (2009)
- Nagappa M, "Neurosyphilis: MRI features and their phenotypic correlation in a cohort of 35patients from a tertiary care university hospital", Neuroradiology, 55, pp.379~388 (2013)
- Kikuchi S, "Subacute syphilitic meningomyelitis with characteristic spinal MRI findings", J Neurol, 250, pp.106~107 (2003)
- Smith MM, "Neurosyphilis as a cause of facial and vestibulocochlear nerve dysfunction: MR imaging features", AJNR Am J Neuroradiol, 21, pp.1673~1675 (2000)
- 장지혜, "뇌간에서 뇌신경을 침범한 신경매독: 2 증례", 대한영상의학회지, 66(1), pp.11~15 (2012), 대한영상의학회
- Seeley WW, "Neurosyphilis presenting with gummatous oculomotor nerve palsy", J Neurol Neurosurg Psychiatry, 75, pp.789~ (2004)
- Ghanem KG, "Review: Neurosyphilis: A historical perspective and review", CNS Neurosci Ther, 16, pp.e157~e168 (2010)