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다발성 뇌신경마비로 발현한 신경매독

Neurosyphilis Presenting with Multiple Cranial Neuropathy

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키워드

주제분류신경과학

초록

Neurosyphilis can present with various clinical symptoms. We report a patient with multiple cranial neuropathy that, mimicked tuberculosis, but was finally diagnosed as neurosyphilis. A 38-year-old man was admitted due to subacutely progressive hearing loss. Brain MRI revealed multiple dural enhanced masses on contrast-enhanced T1 weighted images. Brain biopsy of the dural enhanced lesion revealed chronic granulomatous inflammation with coagulation necrosis, compatible with syphilitic gumma. Serum venereal disease research laboratory and fluorescent treponemal antibody absorption test results were positive. Treatment with penicillin resolved the patient’s symptom.

Abstract

Neurosyphilis can present with various clinical symptoms. We report a patient with multiple cranial neuropathy that, mimicked tuberculosis, but was finally diagnosed as neurosyphilis. A 38-year-old man was admitted due to subacutely progressive hearing loss. Brain MRI revealed multiple dural enhanced masses on contrast-enhanced T1 weighted images. Brain biopsy of the dural enhanced lesion revealed chronic granulomatous inflammation with coagulation necrosis, compatible with syphilitic gumma. Serum venereal disease research laboratory and fluorescent treponemal antibody absorption test results were positive. Treatment with penicillin resolved the patient’s symptom.

참고문헌 (10)

  1. Chung CS, "Neurosyphilis-A study of 85 cases", J Korean Neurol Assoc, 3, pp.29~39 (1985)
  2. Fargen KM, "Cerebral syphilitic gummata : a case presentation and analysis of 156 reported cases", Neurosurgery, 64, pp.568~575 (2009)
  3. Li JC, "Cerebral syphilitic gumma:a case report and review of the literature", Neurol Sci, 33, pp.1179~1181 (2012)
  4. Timmermans M, "Neurosyphilis in the modern era", J Neurol Neurosurg Psychiatry, 75, pp.1727~1730 (2004)
  5. Smith MM, "Neurosyphilis as a cause of facial and vestibulocochlear nerve dysfunction : MR imaging features", AJNR Am J Neuroradiol, 21, pp.1673~1675 (2000)
  6. Nayak S, "VDRL test and its interpretation", Indian J Dermatol, 57, pp.3~8 (2012)
  7. Farazmand P, "Early syphilis mimicking tuberculous meningoencephalitis in an HIV-positive patient", Int J STD AIDS, 21, pp.209~210 (2010)
  8. Kösters K, "Rapid diagnosis of CNS tuberculosis by a T-cell interferon-gamma release assay on cerebrospinal fluid mononuclear cells", Infection, 36, pp.597~600 (2008)
  9. Kim SH, "Diagnosis of central nervous system tuberculosis by T-cell-based assays on peripheral blood and cerebrospinal fluid mononuclear cells", Clin Vaccine Immunol, 15, pp.1356~1362 (2008)
  10. 황정연, "관자동맥염 양상으로 발현한 신경매독", 대한신경과학회지, 29(2), pp.142~144 (2011), 대한신경과학회

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