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A Rare Case of Syphilitic Myelitis of the Spinal Cord

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초록

Neurosyphilis is an infection of the brain or spinal cord that is caused by the bacterium Treponema pallidum . Syphilitic myelitis, which involves the spinal cord, is a very rare form of neurosyphilis seen in patients with syphilis. It requires differentiation from other diseases of the spinal cord, including idiopathic transverse myelitis and spinal cord infarction. Herein, we describe the presentation and diagnosis of syphilitic myelitis in a 43-year-old woman, based on a flip-flop sign and candle guttering appearance depicted in magnetic resonance imaging and laboratory tests.

Abstract

Neurosyphilis is an infection of the brain or spinal cord that is caused by the bacterium Treponema pallidum . Syphilitic myelitis, which involves the spinal cord, is a very rare form of neurosyphilis seen in patients with syphilis. It requires differentiation from other diseases of the spinal cord, including idiopathic transverse myelitis and spinal cord infarction. Herein, we describe the presentation and diagnosis of syphilitic myelitis in a 43-year-old woman, based on a flip-flop sign and candle guttering appearance depicted in magnetic resonance imaging and laboratory tests.

참고문헌 (11)

  1. Pandey S, "Magnetic resonance imaging of the spinal cord in a man with tabes dorsalis", J Spinal Cord Med, 34, pp.609~611 (2011)
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  4. Tsui EY, "Syphilitic myelitis with diffuse spinal cord abnormality on MR imaging", Eur Radiol, 12, pp.2973~2976 (2002)
  5. Tien RD, "Neurosyphilis in HIV carriers: MR findings in six patients", AJR Am J Roentgenol, 158, pp.1325~1328 (1992)
  6. MacLean S, "Finding neurosyphilis without the venereal disease research laboratory test", Sex Transm Dis, 23, pp.392~394 (1996)
  7. Tashiro K, "Syphilitic myelitis with its magnetic resonance imaging (MRI)verification and successful treatment", Jpn J Psychiatry Neurol, 41, pp.269~271 (1987)
  8. Kikuchi S, "Subacute syphilitic meningomyelitis with characteristic spinal MRI findings", J Neurol, 250, pp.106~107 (2003)
  9. Yuan JL, "Clinical features of syphilitic myelitis with longitudinally extensive myelopathy on spinal magnetic resonance imaging", World J Clin Cases, 7, pp.1282~1290 (2019)
  10. Nabatame H, "MRI of syphilitic myelitis", Neuroradiology, 34, pp.105~106 (1992)
  11. Jacob A, "An approach to the diagnosis of acute transverse myelitis", Semin Neurol, 28, pp.105~120 (2008)

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