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Clinical Applications of Neuroimaging with Susceptibility Weighted Imaging: Review Article

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초록

Purpose : Susceptibility-weighted magnetic resonance (MR) sequence is three-dimensional (3D), spoiled gradient-echopulse sequences that provide a high sensitivity for the detection of blood degradation products, calcifications, and irondeposits. This pictorial review is aimed at illustrating and discussing its main clinical applications. Materials and Methods: SWI is based on high-resolution, 3D, fully velocity-compensated gradient-echo sequences usingboth magnitude and phase images. To enhance the visibility of the venous structures, the magnitude images are multipliedwith a phase mask generated from the filtered phase data, which are displayed at best after post-processing of the3D dataset with the minimal intensity projection algorithm. A total of 200 patients underwent MR examinations thatincluded SWI on a 3 tesla MR imager were enrolled. Results: SWI is very useful in detecting multiple brain disorders. Among the 200 patients, 80 showed developmentalvenous anomaly, 22 showed cavernous malformation, 12 showed calcifications in various conditions, 21 showed cerebrovascularaccident with susceptibility vessel sign or microbleeds, 52 showed brain tumors, 2 showed diffuse axonalinjury, 3 showed arteriovenous malformation, 5 showed dural arteriovenous fistula, 1 showed moyamoya disease, and 2showed Parkinson’s disease. Conclusion: SWI is useful in detecting occult low flow vascular lesions, calcification and microbleed and characterisingdiverse brain disorders.

Abstract

Purpose : Susceptibility-weighted magnetic resonance (MR) sequence is three-dimensional (3D), spoiled gradient-echopulse sequences that provide a high sensitivity for the detection of blood degradation products, calcifications, and irondeposits. This pictorial review is aimed at illustrating and discussing its main clinical applications. Materials and Methods: SWI is based on high-resolution, 3D, fully velocity-compensated gradient-echo sequences usingboth magnitude and phase images. To enhance the visibility of the venous structures, the magnitude images are multipliedwith a phase mask generated from the filtered phase data, which are displayed at best after post-processing of the3D dataset with the minimal intensity projection algorithm. A total of 200 patients underwent MR examinations thatincluded SWI on a 3 tesla MR imager were enrolled. Results: SWI is very useful in detecting multiple brain disorders. Among the 200 patients, 80 showed developmentalvenous anomaly, 22 showed cavernous malformation, 12 showed calcifications in various conditions, 21 showed cerebrovascularaccident with susceptibility vessel sign or microbleeds, 52 showed brain tumors, 2 showed diffuse axonalinjury, 3 showed arteriovenous malformation, 5 showed dural arteriovenous fistula, 1 showed moyamoya disease, and 2showed Parkinson’s disease. Conclusion: SWI is useful in detecting occult low flow vascular lesions, calcification and microbleed and characterisingdiverse brain disorders.

참고문헌 (14)

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