Susceptibility-Weighted MR Imaging for the Detection of Developmental Venous Anomaly: Comparison with T2 and FLAIR Imaging
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Purpose : We evaluated the diagnostic value of susceptibility-weighted imaging (SWI) for the detection of developmentalvenous anomaly (DVA). Materials and Methods: Retrospective review of 1068 brain MR examinations found 28 DVAs in 28 patients (2.6%) oncontrast-enhanced T1-weighted images. SWI, T2, and FLAIR images of 28 patients with DVA and 28 sex- and agematchedcontrol patients without DVA were analyzed by blinded readers on each type of sequences. All images wereindependently reviewed by two radiologists who were blinded to other MR imaging finding. In cases of discrepancy, tworeviewers reached a consensus later. The sensitivity, specificity, positive predictive value (PPV), and negative predictivevalue (NPV) of each MR sequence for the detection of DVA were determined. Statistical analysis was performed by usingthe Mcnemar test. The significance level was p < 0.05. Results: The sensitivity, specificity, PPV, and NPV of SWI for the detection of DVA were 85.7%, 92.9%, 92.3%, and86.7%, respectively. T2 and FLAIR images showed sensitivity of 35.7% and 35.7%, specificity of 92.9% and 96.4%, PPVof 83.3% and 90.9%, and NPV of 59.1% and 60.0%, respectively. On SWI, the sensitivity and NPV for the detection ofDVAs were significantly higher than those of T2 and FLAIR images (p < 0.05). Conclusion: SWI was sensitive and specific for the detection of DVA.
Abstract
Purpose : We evaluated the diagnostic value of susceptibility-weighted imaging (SWI) for the detection of developmentalvenous anomaly (DVA). Materials and Methods: Retrospective review of 1068 brain MR examinations found 28 DVAs in 28 patients (2.6%) oncontrast-enhanced T1-weighted images. SWI, T2, and FLAIR images of 28 patients with DVA and 28 sex- and agematchedcontrol patients without DVA were analyzed by blinded readers on each type of sequences. All images wereindependently reviewed by two radiologists who were blinded to other MR imaging finding. In cases of discrepancy, tworeviewers reached a consensus later. The sensitivity, specificity, positive predictive value (PPV), and negative predictivevalue (NPV) of each MR sequence for the detection of DVA were determined. Statistical analysis was performed by usingthe Mcnemar test. The significance level was p < 0.05. Results: The sensitivity, specificity, PPV, and NPV of SWI for the detection of DVA were 85.7%, 92.9%, 92.3%, and86.7%, respectively. T2 and FLAIR images showed sensitivity of 35.7% and 35.7%, specificity of 92.9% and 96.4%, PPVof 83.3% and 90.9%, and NPV of 59.1% and 60.0%, respectively. On SWI, the sensitivity and NPV for the detection ofDVAs were significantly higher than those of T2 and FLAIR images (p < 0.05). Conclusion: SWI was sensitive and specific for the detection of DVA.
참고문헌 (26)
- Lasjaunias P, "Developmental venous anomalies (DVA): the so-called venous angioma", Neurosurg Rev, 9, pp.233~242 (1986)
- Sarwar M, "Intracerebral venous angioma. Case report and review", Arch Neurol, 35, pp.323~325 (1978)
- Truwit CL, "Venous angioma of the brain: history, significance, and imaging findings", AJR Am J Roentgenol, 159, pp.1299~1307 (1992)
- Takasugi M, "Parenchymal hypointense foci associated with developmental venous anomalies: evaluation by phase-sensitive MR imaging at 3T", AJNR Am J Neuroradiol, 34, pp.1940~1944 (2013)
- Santucci GM, "Brain parenchymal signal abnormalities associated with developmental venous anomalies: detailed MR imaging assessment", AJNR Am J Neuroradiol, 29, pp.1317~1323 (2008)
- San Millan Rulz D, "Parenchymal abnormalities associated with developmental venous anomalies", Neuroradiology, 49, pp.987~995 (2007)
- Daftari Besheli L, "Current status of nephrogenic systemic fibrosis", Clin Radiol, 69, pp.661~668 (2014)
- Huang P, "Clinical applications of susceptibility weighted imaging in patients with major stroke", J Neurol, 259, pp.1426~1432 (2012)
- Santhosh K, "Susceptibility weighted imaging: a new tool in magnetic resonance imaging of stroke", Clin Radiol, 64, pp.74~83 (2009)
- Haacke EM, "Susceptibility weighted imaging (SWI)", Magn Reson Med, 52, pp.612~618 (2004)
- Mittal S, "Susceptibilityweighted imaging: technical aspects and clinical applications, part 2", AJNR Am J Neuroradiol, 30, pp.232~252 (2009)
- Tsui YK, "Susceptibility-weighted imaging for differential diagnosis of cerebral vascular pathology: a pictorial review", J Neurol Sci, 287, pp.7~16 (2009)
- Haacke EM, "Susceptibility-weighted imaging: technical aspects and clinical applications, part 1", AJNR Am J Neuroradiol, 30, pp.19~30 (2009)
- McCormick WF, "Vascular malformations (“angiomas”) of the dura mater", J Neurosurg, 25, pp.309~311 (1966)
- Ruiz DS, "Cerebral developmental venous anomalies: current concepts", Ann Neurol, 66, pp.271~283 (2009)
- San Millan Ruiz D, "Cerebral developmental venous anomalies", Childs Nerv Syst, 26, pp.1395~1406 (2010)
- Garner TB, "The natural history of intracranial venous angiomas", J Neurosurg, 75, pp.715~722 (1991)
- Lee BC, "MR high-resolution blood oxygenation level dependent venography of occult (low-flow)vascular lesions", AJNR Am J Neuroradiol, 20, pp.1239~1242 (1999)
- Sehgal V, "Clinical applications of neuroimaging with susceptibility-weighted imaging", J Magn Reson Imaging, 22, pp.439~450 (2005)
- Tong KA, "Susceptibility-weighted MR imaging: a review of clinical applications in children", AJNR Am J Neuroradiol, 29, pp.9~17 (2008)
- Thomas B, "Clinical applications of susceptibility weighted imaging of brain-A pictorial review", Neuroradiology, 50, pp.105~116 (2008)
- Huber G, "Regional association of developmental venous anomalies with angiographically occult vascular malformations", Eur Radiol, 6, pp.30~37 (1996)
- de Souza JM, "Susceptibilityweighted imaging for the evaluation of patients with familial cerebral cavernous malformations: a comparison with T2-weighted fast spin-echo and gradient-echo sequences", AJNR Am J Neuroradiol, 29, pp.154~158 (2008)
- de Champfleur NM, "Magnetic resonance imaging evaluation of cerebral cavernous malformations with susceptibility-weighted imaging", Neurosurgery, 68, pp.641~647 (2011)
- McLaughlin MR, "The prospective natural history of cerebral venous malformations", Neurosurgery, 43, pp.195~200 (1998)
- Jung HN, "Diffusion and perfusion MRI findings of the signal-intensity abnormalities of brain associated with developmental venous anomaly", AJNR Am J Neuroradiol (2014)