MRI Findings for IgG4-Related Disease Involving the Liver and Gallbladder
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Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated condition characterized by the infiltration of IgG4-positive plasma cells, increased serum IgG4 levels, and the development of mass-forming lesions. Involvement of the liver or gallbladder in IgG4-RD is uncommon. In this study, we report the magnetic resonance imaging findings of a hepatic inflammatory pseudotumor (IPT) and sclerosing cholecystitis in a 64-year-old male patient with IgG4-RD. IgG4-related hepatic IPT demonstrated intermediate signal intensity (SI) on T2-weighted images (T2WI), whereas no significant enhancement was observed in a T1- weighted dynamic study. Additionally, diffusion restrictions were not exhibited. IgG4-related sclerosing cholecystitis presented as a mass-forming lesion. It exhibited a low SI on T2WI, demonstrated prolonged enhancement during the arterial, portal venous, and transitional phases of T1-weighted dynamic studies, and did not exhibit prominent diffusion restriction.
Abstract
Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated condition characterized by the infiltration of IgG4-positive plasma cells, increased serum IgG4 levels, and the development of mass-forming lesions. Involvement of the liver or gallbladder in IgG4-RD is uncommon. In this study, we report the magnetic resonance imaging findings of a hepatic inflammatory pseudotumor (IPT) and sclerosing cholecystitis in a 64-year-old male patient with IgG4-RD. IgG4-related hepatic IPT demonstrated intermediate signal intensity (SI) on T2-weighted images (T2WI), whereas no significant enhancement was observed in a T1- weighted dynamic study. Additionally, diffusion restrictions were not exhibited. IgG4-related sclerosing cholecystitis presented as a mass-forming lesion. It exhibited a low SI on T2WI, demonstrated prolonged enhancement during the arterial, portal venous, and transitional phases of T1-weighted dynamic studies, and did not exhibit prominent diffusion restriction.
참고문헌 (9)
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