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논문KCI 등재

足三里穴 전침 자극이 유문부 부분폐색이 된 흰 쥐의 胃 배출능에 미치는 효능

Effect of Zusanli(ST36) Electroacupuncture Stimulation on Delayed Gastric Emptying in Rats with Partial Pyloric Obstruction

윤상협|홍인아
대한한방내과학회 (The Society Of Korean Oriental Internal Medicine)|2009.03|대한한방내과학회지 (The Journal of Korean Oriental Internal Medicine)|제30권 제1호|pp. 1-8

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참고문헌

키워드

ElectroacupunctureAntropyloric FlowGastric EmptyingPyloric Obstruction
주제분류한의학

초록

Objective : The aims of this study were to observe how body weight and gastric morphology were changed and whether gastric emptying was impaired in rats with partial pyloric obstruction and to evaluate whether electroacupuncture was able to restore delayed gastric emptying. Methods : Partial pyloric obstruction was induced by wrapping a nonabsorbable rubber ring around the 1st portion of the duodenum for 2 weeks. Body gain and morphologic changes of stomach were investigated and compared with normal intact rats. Gastric emptying was measured by numbering expelled glass of beads in rats. Rats were divided into 4 groups(non-acupuncture, manual acupuncture, 3Hz-electroacupuncture, 60Hz-electroacupuncture). Stimulus intensity in two electroacupuncture groups was 1.2 times of pain threshold. Results : Partial pyloric obstruction produced a significant loss of boby weight and insuced a significant increase of gastric surface area. The 60Hz electroacupuncture stimulated group significantly restored the delayed gastric emptying than the other groups in rats with partial pyloric obstruction. Conclusion : 60Hz electroacupuncture stimulation on Zusanli(ST36) showed siginificant restoration of delayed gastric emptying in rats with partial pyloric obstruction.

Abstract

Objective : The aims of this study were to observe how body weight and gastric morphology were changed and whether gastric emptying was impaired in rats with partial pyloric obstruction and to evaluate whether electroacupuncture was able to restore delayed gastric emptying. Methods : Partial pyloric obstruction was induced by wrapping a nonabsorbable rubber ring around the 1st portion of the duodenum for 2 weeks. Body gain and morphologic changes of stomach were investigated and compared with normal intact rats. Gastric emptying was measured by numbering expelled glass of beads in rats. Rats were divided into 4 groups(non-acupuncture, manual acupuncture, 3Hz-electroacupuncture, 60Hz-electroacupuncture). Stimulus intensity in two electroacupuncture groups was 1.2 times of pain threshold. Results : Partial pyloric obstruction produced a significant loss of boby weight and insuced a significant increase of gastric surface area. The 60Hz electroacupuncture stimulated group significantly restored the delayed gastric emptying than the other groups in rats with partial pyloric obstruction. Conclusion : 60Hz electroacupuncture stimulation on Zusanli(ST36) showed siginificant restoration of delayed gastric emptying in rats with partial pyloric obstruction.

참고문헌 (25)

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