한방치료가 위 미주신경 활성 저하와 유문부 기능 장애가 병발된 기능성 소화불량증 환자에 미치는 선택적 효능
A Selective Effect of Combined Treatment of Electroacupuncture at Zusanli(ST36), Manual Acupuncture, And Pyengwisan in Function Dyspepsia Patients with Pyloric Valve Disturbance And Hypoactivity of Gastric Vagus Nerve
2
조회
0
다운로드
7
인용
0
참고문헌
키워드
초록
Objectives : The aim of this study was to evaluate therapeutic effect of acupuncture and herbal medicine in patients who had the hypoacivity of gastric vagus nerve and pyloric valve disturbance simultaneously with function dyspepsia by bowel sounds analysis. Methods : Bowel sounds of 10 patients(male 1, female 9) were recorded and their % of bowel sound (%BS) and ratio of dominant frequency(DF) were analyzed before and after treatment. Hypoactivity of gastric vagus nerve was considered if % BS was <6%, and pyloric valve disturbance was accepted if DF ratio(eg, postprandial DF/fasting DF) was <1. Electroacupuncture at Zusanli(ST36, 3Hz, 30minutes) and manual acupuncture at other meridian points were applied daily for 2 weeks. Herbal medicine, Pyengwisan, was administered to all patients(100cc, 3 times/day). Results : DF ratio significantly increased from 0.93±0.06 to 1.06±0.04after treatment for 2 weeks(p=0.005). 9 of 10 patients were improved to DF ratio>1. %BS also increased from 2.97±1.17% to 4.49±4.27%, not significantly. 3 patients showed a remarkable elevation, and their %BS reached >6% of normal value. Conclusions : Combined effect of electroacupuncture at Zusanli(ST36), manual acupuncture, and Pyengwisan was shown more effective in the improvement of pyloric valve disturbance more than hypoactivity of gastric vagus nerve on patients with functional dyspepsia.
Abstract
Objectives : The aim of this study was to evaluate therapeutic effect of acupuncture and herbal medicine in patients who had the hypoacivity of gastric vagus nerve and pyloric valve disturbance simultaneously with function dyspepsia by bowel sounds analysis. Methods : Bowel sounds of 10 patients(male 1, female 9) were recorded and their % of bowel sound (%BS) and ratio of dominant frequency(DF) were analyzed before and after treatment. Hypoactivity of gastric vagus nerve was considered if % BS was <6%, and pyloric valve disturbance was accepted if DF ratio(eg, postprandial DF/fasting DF) was <1. Electroacupuncture at Zusanli(ST36, 3Hz, 30minutes) and manual acupuncture at other meridian points were applied daily for 2 weeks. Herbal medicine, Pyengwisan, was administered to all patients(100cc, 3 times/day). Results : DF ratio significantly increased from 0.93±0.06 to 1.06±0.04after treatment for 2 weeks(p=0.005). 9 of 10 patients were improved to DF ratio>1. %BS also increased from 2.97±1.17% to 4.49±4.27%, not significantly. 3 patients showed a remarkable elevation, and their %BS reached >6% of normal value. Conclusions : Combined effect of electroacupuncture at Zusanli(ST36), manual acupuncture, and Pyengwisan was shown more effective in the improvement of pyloric valve disturbance more than hypoactivity of gastric vagus nerve on patients with functional dyspepsia.
참고문헌 (25)
- Geeraerts B, "Functional dyspepsia: past, present, and future", J Gastroenterol, 43(4), pp.251~255 (2008)
- Tatsuta M, "Effect of treatment with liu-jun-zi-tang (TJ-43) on gastric emptying and gastrointestinal symptoms in dyspeptic patients", Aliment Pharmacol Ther, 7(4), pp.459~462 (1993)
- Oikawa T, "Prokinetic effect of a Kampo medicine, Hange- koboku-to (Banxia-houpo-tang), on patients with functional dyspepsia", Phytomedicine, 12(10), pp.730~734 (2005)
- Xu S, "Electroacupuncture accelerates solid gastric emptying and improves dyspeptic symptoms in patients with functional dyspepsia", Dig Dis Sci, 51(12), pp.2154~2159 (2006)
- 김유승, "기능성 소화불량증 환자의 위 미주신경 활성 및 유문부 기능에 대한 足三里 전침과 일반 체침 자극의 복합 효능", 대한한방내과학회지, 29(3), pp.621~628 (2008), 대한한방내과학회
- 윤상협, "機能性 消化不良症 患者의 食後 心下?滿과 pyloric valve의 機能障碍 - 장음과 위전도를 중심으로", 대한한방내과학회지, 28(4), pp.769~778 (2007), 대한한방내과학회
- Cannon WB, "Auscultation of the rhythmic sounds produced by the stomach and intestine", Am J Physiol, 14, pp.339~353 (1905)
- Arnbjornsson E, "The role of auscultation and registration of bowel sounds in the diagnosis of acute appendicitis", Ann Chir Gynaecol, 72(6), pp.324~328 (1983)
- Politzer JP, "The genesis of bowel sounds: influence of viscus and gastrointestinal content", Gastroenterology, 71(2), pp.282~285 (1976)
- Yamaguchi K, "Evaluation of gastrointestinal motility by computerized analysis of abdominal auscultation findings", J Gastroenterol Hepatol, 21(3), pp.510~514 (2006)
- Craine BL, "Two-dimensional positional mapping of gastrointestinal sounds in control and functional bowel syndrome patients", Dig Dis Sci, 47(6), pp.1290~1296 (2002)
- Watson WC, "Phonoenterography: the recording and analysis of bowel sounds", Gut, 8(1), pp.88~94 (1967)
- Tomomasa T, "Analysis of gastrointestinal sounds in infants with pyloric stenosis before and after pyloromyotomy", Pediatrics, 104(5), pp.e60~ (1999)
- Tomomasa T, "Gastrointestinal sounds and migrating motor complex in fasted humans", Am J Gastroenterol, 94(2), pp.374~381 (1999)
- Farrar JT, "Gastrointestinal motility as revealed by study of abdominal sounds", Gastroenterology, 29(5), pp.789~802 (1955)
- 홍인아, "기능성 소화불량증 환자의 위장관 부교감 신경, 위 유문부의 기능 및 임상양상에 대한 조사 (한방병원 내원 환자를 중심으로)", 대한한방내과학회지, 29(3), pp.666~674 (2008), 대한한방내과학회
- Locke GR, 3rd, "Familial association in adults with functional gastrointestinal disorders", Mayo Clin Proc, 75(9), pp.907~912 (2000)
- van Lelyveld N, "Candidate genotypes associated with functional dyspepsia", Neurogastroenterol Motil, 20(7), pp.767~773 (2008)
- Arisawa T, "Genetic polymorphisms of cyclooxygenase-1 (COX-1) are associated with functional dyspepsia in Japanese women", J Womens Health (Larchmt), 17(6), pp.1039~1043 (2008)
- Noguchi E, "Mechanism of reflex regulation of the gastroduodenal function by acupuncture", Evid Based Complement Alternat Med, 5(3), pp.251~256 (2008)
- Takahashi T, "Acupuncture for functional gastrointestinal disorders", J Gastroenterol, 41(5), pp.408~417 (2006)
- Kametani H, "Neural mechanisms of reflex facilitation and inhibition of gastric motility to stimulation of various skin areas in rats", J Physiol, 294, pp.407~418 (1979)
- Qian LW, "Effect of electroacupuncture at zusanli (ST36) point in regulating the pylorus peristaltic function", Zhongguo Zhong Xi Yi Jie He Za Zhi, 13(6), pp.336~339 (1993)
- Allescher HD, "Extrinsic and intrinsic neural control of pyloric sphincter pressure in the dog", J Physiol, 401, pp.17~38 (1988)
- 홍종희, "消積健脾丸顆粒이 흰쥐의 胃運動性에 미치는 영향", 대한한방내과학회지, 27(1), pp.276~287 (2006), 대한한방내과학회
