사료 내 nucleotide 첨가가 틸라피아O(reochromis niloticus)의 성장, 사료효율 및 비특이적 면역력에 미치는 영향
Effects of Dietary Supplementation with Nucleotide on Growth Performance, Feed Utilization, and Non-Specific Immune Responses of Nile Tilapia Oreochromis niloticus
2
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
The present study examined the effects of dietary supplementation with nucleotide (inosine monophosphate product, IMP) on the growth performance, feed utilization, and non-specific immune responses of juvenile tilapia Oreochromis niloticus. Triplicate groups of tilapia (initial body weight, 7.4±0.04 g) were fed experimental diets containing 0%, 0.05%, 0.1%, and 0.2% IMP. Fish were fed six times a day until apparent satiation for 13 weeks. At the end of the feeding trial, final body weight and food utilization of fish fed 0.1% IMP were significantly higher than those of fish fed the control diet. Results of hematological parameters were not affected by dietary IMP. However, blood protein level was significantly higher in the 0.05% treatment, as compared to that of the control and 0.2% IMP diets. Myeloperoxidase activity was higher in fish fed 0.1% IMP than in fish fed the control and 0.2%IMP diets. These results suggest that dietary supplementation with IMP can enhance the growth performance, feed utilization, and innate immune response of juvenile tilapia. The optimal IMP supplementation level appears to be 0.1% in practical feed formulations for tilapia.
Abstract
The present study examined the effects of dietary supplementation with nucleotide (inosine monophosphate product, IMP) on the growth performance, feed utilization, and non-specific immune responses of juvenile tilapia Oreochromis niloticus. Triplicate groups of tilapia (initial body weight, 7.4±0.04 g) were fed experimental diets containing 0%, 0.05%, 0.1%, and 0.2% IMP. Fish were fed six times a day until apparent satiation for 13 weeks. At the end of the feeding trial, final body weight and food utilization of fish fed 0.1% IMP were significantly higher than those of fish fed the control diet. Results of hematological parameters were not affected by dietary IMP. However, blood protein level was significantly higher in the 0.05% treatment, as compared to that of the control and 0.2% IMP diets. Myeloperoxidase activity was higher in fish fed 0.1% IMP than in fish fed the control and 0.2%IMP diets. These results suggest that dietary supplementation with IMP can enhance the growth performance, feed utilization, and innate immune response of juvenile tilapia. The optimal IMP supplementation level appears to be 0.1% in practical feed formulations for tilapia.
참고문헌 (34)
- Adamek Z, "Effect of Ascogen probiotics supplementation on farming success in rainbow trout (Oncorhynchus mykiss ) and wels (Silurus glais ) under conditions of intensive culture", Krmiva (Zagreb), 38, pp.11~20 (1996)
- AOAC, "Official methods of analysis. 16th ed", pp.1298~ (1995), Association of Official Analytical Chemists
- Carver J, "Dietary nucleotide effects upon murine natural killer cell activity and macrophage activation", J Parenter Enteral Nutr, 14, pp.18~22 (1990)
- Carver JD, "The role of nucleotides in human nutrition", J Nutr Biochem, 6, pp.58~72 (1995)
- Cheng Z, "Dietary nucleotides influence immune responses and intestinal morphology of red drum Sciaenops ocellatus", Fish Shellfish Immunol, 30, pp.143~147 (2011)
- Cosgrove M, "Nucleotides", Nutrition, 14, pp.748~751 (1998)
- El-Sayed AFM, "Tilapia Culture" (2006), CABI Publishing
- Folch J, "A simple method for the isolation and purification of total lipids from animal tissues", J Biol Chem, 226, pp.497~509 (1957)
- Gil A, "Modulation of the immune responses mediated by dietary nucleotides", Eur Clin Nutr, 56, pp.1~4 (2002)
- Grimble GK, "Nucleotides, In Nutrition and Immunology: Principles and Practice", pp.135~144 (2000), Humana Press Inc
- Hardy RW, "Fish meal: Historical uses, production trends, and future outlook for sustainable supplies, In Responsible Marine Aquaculture", pp.311~325 (2002), CABI Publishing
- Jha AK, "Haemato-immunological responses to dietary yeast RNA, ω-3 fatty acid and β-carotene in Catla catla juveniles", Fish Shellfish Immunol, 23, pp.917~927 (2007)
- Kim SS, "Effects of dietary kelp (Ecklonia cava ) on growth and innate immunity in juvenile olive flounder Paralichthys olivaceus", Aquac Res, 39, pp.1687~1690 (2008)
- Sung-Sam Kim, "Effects of Dietary Supplementation of a Meju, Fermented Soybean Meal, and Aspergillus oryzae for Juvenile Parrot Fish (Oplegnathus fasciatus)", ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES, 22(6), pp.849~856 (2009), 아세아·태평양축산학회
- 김성삼, "저수온기 넙치 치어에 있어서 발효마늘분말의 사료 내 첨가가 면역반응, 혈액성분 및 주요 어병세균에 대한 질병저항성에 미치는 영향", 한국동물자원과학회지, 52(4), pp.337~346 (2010), 한국동물자원과학회
- Kiyohara S, "Gustatory response in the puffer-II. Single fiber analysis", Bull Jpn Soc Sci Fish, 41, pp.383~391 (1975)
- Kubitza F, "Identification of feed enhancers for juvenile largemouth bass, Micropterus salmoides", Aquaculture, 148, pp.191~200 (1997)
- Kumar S, "Effect of dietary carbohydrate on haematology, respiratory burst activity and histological changes in L. rohita juveniles", Fish Shellfish Immunol, 19, pp.331~344 (2005)
- Kumari J, "Effects of cyclophosphamide on the immune system and disease resistance of Asian catfish Clarias batrachus", Fish Shellfish Immunol, 19, pp.307~316 (2005)
- J East Coastal Res, "Effects of herb as an additive in formulated diet on growth and body composition of larval ayu (Plecoglossus altivelis )", J East Coastal Res, 11, pp.35~42 (2000)
- Li P, "Nucleotide nutrition in fish: Current knowledge and future applications", Aquaculture, 251, pp.141~152 (2006)
- Li P, "Dietary supplementation of a purified nucleotide mixture transiently enhanced growth and feed utilization of juvenile red drum, Sciaenops ocellatus", J World Aquacult Soc, 38, pp.281~286 (2007)
- Lin YH, "Dietary nucleotide supplementation enhances growth and immune responses of grouper, Epinephelus malabaricus", Aquacult Nutr, 15, pp.117~122 (2009)
- Low C, "Expression of immune genes in turbot (Scophthalmus maximus ) fed a nucleotide-supplemented diet", Aquaculture, 221, pp.23~40 (2003)
- Mackie AM., "The chemical basis of food detection in the lobster Homarus gammarus", Mar Biol, 21, pp.103~108 (1973)
- Mateo CD, "Nucleotide deficiencies in starter diets for weanling pigs. Nutritional biotechnology in the feed industry", In: Proceedings of Alltech’s 20th annual symposium, pp.1~55 (2004)
- Rudolph FB., "The biochemistry and physiology of nucleotides", J Nutr, 124, pp.124~127 (1994)
- Sakai M, "Immunostimulant effects of nucleotide isolated fromyeast RNA on carp, Cyprinus carpio L", J Fish Dis, 24, pp.433~438 (2001)
- Sankaran K, "On the variation in catalytic activity of lysozyme in fishes", Indian J Biochem Biophys, 91, pp.162~165 (1972)
- Shiau SY, "Dietary supplementation of chitin and chitosan depresses growth in tilapia, Oreoxhromis niloticus×O. aureus", Aquaculture, 179, pp.439~446 (1999)
- 송진우, "사료 내 해조류(톳, 감태) 첨가가 돌돔(Oplegnathus fasciatus) 치어의 비특이적 면역반응에 미치는 영향", 한국수산과학회지, 44(4), pp.332~338 (2011), 한국수산과학회
- Tacon AGF, "Fishing for aquaculture: nonfood use of small pelagic forage fish-a global perspective", Rev Fish Sci, 17, pp.305~317 (2009)
- Tahmasebi-Kohyani A, "Dietary administration of nucleotides to enhance growth, humoral immune responses, and disease resistance of the rainbow trout (Oncorhynchus mykiss ) fingerlings", Fish Shellfish Immunol, 30, pp.189~193 (2011)
- Welker TL, "Effects of dietary supplementation of a purified nucleotide mixture on immune function and disease and stress resistance in channel catfish, Ictalurus punctatus", Aquac Res, 42, pp.1878~1889 (2011)
