어류 양식장에서 분리한 Vibrio parahaemolyticus의 Class Ⅰ Integron에 의한 Trimethoprim 내성
Trimethoprim Resistance by Class Ⅰ Integron in Vibrio parahaemolyticus from a Fish Farm
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초록
A trimethoprim resistant Vibrio parahaemolyticus, which cause acute gastroenteritis in humans, was isolated from farmed fish and seawater. The resistance profiles of isolated V. parahaemolyticus and their correlation with mobile elements were investigated. All of the V. parahaemolyticus were resistance to both rifampin and trimethoprim. The presence of class Ⅰ integron was confirmed by PCR. PCR-amplified inserted gene cassettes contained aminoglycoside aac6-Ⅱ, rifampin arr-3 and trimethoprim dfrA27 resistance genes. This study indicated that class Ⅰ integron mainly contributed to the circulation of trimethoprim resistance determinants in V. parahaemolyticus.
Abstract
A trimethoprim resistant Vibrio parahaemolyticus, which cause acute gastroenteritis in humans, was isolated from farmed fish and seawater. The resistance profiles of isolated V. parahaemolyticus and their correlation with mobile elements were investigated. All of the V. parahaemolyticus were resistance to both rifampin and trimethoprim. The presence of class Ⅰ integron was confirmed by PCR. PCR-amplified inserted gene cassettes contained aminoglycoside aac6-Ⅱ, rifampin arr-3 and trimethoprim dfrA27 resistance genes. This study indicated that class Ⅰ integron mainly contributed to the circulation of trimethoprim resistance determinants in V. parahaemolyticus.
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