Herbal Medicine for Liver Cancer: A Protocol for Systematic Review and Meta-Analysis
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Introduction: The aim of this systematic review is to provide evidence confirming the efficacy and safety of herbal medicines used in the treatment of liver cancer. Methods: The review will include randomized clinical trials that compared herbal medicines used as treatments for liver cancer with other therapies, such as placebos and Western medicine. Only randomized controlled trials will be included in this review, and all types of herbal medicine will be evaluated. Eleven electronic databases will be searched from the inception date: the Cochrane Database of Systematic Reviews, MEDLINE, EMBASE, AMED, CINAHL, one Chinese database (CNKI), and five Korean databases (OASIS, DBpia, RISS, KISS, and NDSL). The selection of studies, data extraction, and management will be performed independently by four researchers. Methodological quality, including the risk of bias, will be assessed using the Cochrane risk-of-bias assessment tool. Results: The review of current evidence for the effectiveness of herbal medicine for liver cancer will be summarized and quantitatively analyzed. Conclusions: Our systematic review will provide evidence of the efficacy of herbal medicines as treatments for liver cancer. This evidence will provide useful information for practitioners and patients in the fields of oncology and complementary medicine. Systematic review registration: 2021 CRD42021268386
Abstract
Introduction: The aim of this systematic review is to provide evidence confirming the efficacy and safety of herbal medicines used in the treatment of liver cancer. Methods: The review will include randomized clinical trials that compared herbal medicines used as treatments for liver cancer with other therapies, such as placebos and Western medicine. Only randomized controlled trials will be included in this review, and all types of herbal medicine will be evaluated. Eleven electronic databases will be searched from the inception date: the Cochrane Database of Systematic Reviews, MEDLINE, EMBASE, AMED, CINAHL, one Chinese database (CNKI), and five Korean databases (OASIS, DBpia, RISS, KISS, and NDSL). The selection of studies, data extraction, and management will be performed independently by four researchers. Methodological quality, including the risk of bias, will be assessed using the Cochrane risk-of-bias assessment tool. Results: The review of current evidence for the effectiveness of herbal medicine for liver cancer will be summarized and quantitatively analyzed. Conclusions: Our systematic review will provide evidence of the efficacy of herbal medicines as treatments for liver cancer. This evidence will provide useful information for practitioners and patients in the fields of oncology and complementary medicine. Systematic review registration: 2021 CRD42021268386
참고문헌 (9)
- Bosman FT, "WHO classification of tumours of the digestive system", pp.251~253 (2010), World Health Organization
- Motola-Kuba D, "Hepatocellular carcinoma. An overview", Annals of hepatology, 5(1), pp.16~24 (2006)
- Yang JD, "A global view of hepatocellular carcinoma : trends, risk, prevention and management", Nature Reviews Gastroenterology & Hepatology, 16(10), pp.589~604 (2019)
- Bray F, "Global cancer statistics 2018 : GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries", CA Cancer J Clin, 68(6), pp.394~424 (2018)
- Liu CY, "Treatment of Liver Cancer", Cold Spring Harb Perspect Med, 5(9), pp.a021535~ (2015)
- Ma L, "Effect of traditional Chinese medicine combined with Western therapy on primary hepatic carcinoma : a systematic review with meta-analysis", Front Med, 11(2), pp.191~202 (2017)
- Wu P, "Traditional Chinese Medicines in the treatment of hepatocellular cancers : a systematic review and meta-analysis", J Exp Clin Cancer Res, 28(1), pp.112~ (2009)
- Higgins JPT, "Cochrane Handbook for Systematic Reviews of Interventions version 6.0" (2019), Cochrane
- Egger M, "Bias in meta-analysis detected by a simple, graphical test", BMJ, 315(7109), pp.629~634 (1997)