아밀로이드증을 동반한 다발골수종 환자의 자가말초혈액조혈모세포 이식 전 유도항암화학요법 후 발생한 말초신경병증에 대한 복합 한의 치험 1례
A Case Report of Peripheral Neuropathy after Induction Chemotherapy before Autologous Peripheral Blood Stem Cell Transplantation in a Patient with Multiple Myeloma with Amyloidosis Treated with Complex Korean Medicine Treatment
2
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
Introduction: We present a case of multiple myeloma with amyloidosis, which has features of peripheral neuropathy after induction chemotherapy before autologous peripheral blood stem cell transplantation, in a 56-year-old woman with Korean medicine. Case Presentation: For 17 days of hospitalization, the patient with complaints of numbness and a tingling sensation in the hands and feet was treated with acupuncture, herbal medicine. To reduce the symptoms, we provided Korean medicine treatments, including herbal medicine, acupuncture, and moxibustion. The Visual Analog Scale (VAS) was used to evaluate the results of the treatment. Until discharge, the VAS scores decreased for both hands and the foot tingling sensation. Conclusion: According to these results, Korean medicine treatment may be considered an effective treatment for tingling sensations in a patient with multiple myeloma with amyloidosis. Prospective studies are needed in the future to confirm and expand these findings.
Abstract
Introduction: We present a case of multiple myeloma with amyloidosis, which has features of peripheral neuropathy after induction chemotherapy before autologous peripheral blood stem cell transplantation, in a 56-year-old woman with Korean medicine. Case Presentation: For 17 days of hospitalization, the patient with complaints of numbness and a tingling sensation in the hands and feet was treated with acupuncture, herbal medicine. To reduce the symptoms, we provided Korean medicine treatments, including herbal medicine, acupuncture, and moxibustion. The Visual Analog Scale (VAS) was used to evaluate the results of the treatment. Until discharge, the VAS scores decreased for both hands and the foot tingling sensation. Conclusion: According to these results, Korean medicine treatment may be considered an effective treatment for tingling sensations in a patient with multiple myeloma with amyloidosis. Prospective studies are needed in the future to confirm and expand these findings.
참고문헌 (19)
- Raab MS, "Multiple myeloma", Lancet, 374(9686), pp.324~339 (2009)
- Kyle RA, "Primary systemic amyloidosis : clinical and laboratory features in 474 cases", Semin Hematol, 32(1), pp.45~59 (1995)
- Wang AK, "Patterns of neuropathy and autonomic failure in patients with amyloidosis", Mayo Clin Proc, 83(11), pp.1226~1230 (2008)
- Argyriou AA, "Bortezomib-induced peripheral neuropathy in multiple myeloma : a comprehensive review of the literature", Blood, 112(5), pp.1593~1599 (2008)
- 박지혜, "항암화학요법 유발 말초신경병증 변증평가도구개발을 위한 기초연구", 대한한방내과학회지, 37(1), pp.77~89 (2016), 대한한방내과학회
- Association of Korean Medicine Professors for Cardiovascular and Neurological Medicine, "Cardiovascular and Neurological Medicine in Korean Medicine I", pp.289~308 (2018), Wooripub
- Alexanian R, "Amyloidosis in multiple myeloma or without apparent cause", Arch Intern Med, 144(11), pp.2158~2160 (1984)
- 김형종, "유전분증의 임상적 특징", Kidney Research and Clinical Practice, 24(2), pp.230~238 (2005), 대한신장학회
- Comenzo RL, "Autologous stem cell transplantation for primary systemic amyloidosis", Blood, 99(12), pp.4276~4282 (2002)
- Jaccard A, "High-Dose Melphalan versus Melphalan plus Dexamethasone for AL Amyloidosis", N Engl J Med, 357(11), pp.1083~1093 (2007)
- Han Y, "Pathobiology of cancer chemotherapy-induced peripheral neuropathy(CIPN)", Front Pharmacol, 4, pp.156~ (2013)
- Kono T, "Efficacy of goshajinkigan for peripheral neurotoxicity of oxaliplatin in patients with advanced or recurrent colorectal cancer", Evidence-based complementary and alternative medicine, 2011, pp.418481~ (2011)
- Richardson PG, "Frequency, characteristics, and reversibility of peripheral neuropathy during treatment of advanced multiple myeloma with bortezomib", J Clin Oncol, 24(19), pp.3113~3120 (2006)[DOI]
- Kyle RA, "Peripheral Neuropathy", pp.2427~2451 (2005), Elsevier Saunders
- Kerckhove N, "Long-term effects, pathophysiological mechanisms, and risk factors of chemotherapy-induced peripheral neuropathies : a comprehensive literature review", Front Pharmacol, 8, pp.86~ (2017)
- Piccolo J, "Prevention and treatment of chemotherapy-induced peripheral neuropathy", Am J Health Syst Pharm, 71(1), pp.19~25 (2014)
- Kaku H, "Objective evaluation of the alleviating effects of Goshajinkigan on peripheral neuropathy induced by paclitaxel", carboplatin therapy : A multicenter collaborative study, 2012, pp.3(1), 60~65
- Nationwide College of Korean Medicine Faculty Council of Cardiology Internal Medicine, "Cardiovascular and Neurological Medicine in Korean Medicine", pp.273~282 (2016), Woori pub
- 이지혜, "항암화학요법으로 인한 말초신경병증 환자의 한방치험 1례", 동의생리병리학회지, 28(5), pp.565~570 (2014), 한의병리학회