항암화학요법으로 유발된 만성 말초신경병증 환자의 한의학적 치험 1례 : 2년 이상 지속된 항암화학요법 유발 말초신경병증 치험
A Case Report of Chronic Chemotherapy-Induced Peripheral Neuropathy Treated by Korean Traditional Medicine
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초록
Objective: This study reports the effect of Korean traditional medicine on persistent chemotherapy-induced peripheral neuropathy (CIPN). Methods: The patient was treated with Korean traditional medicine that included acupuncture, moxibustion, and herbal medicine. The effectiveness of the treatment was evaluated by the Quality of Life Questionnaire-Core 30 (QLQ-C30), the Quality of Life Questionnaire Chemotherapy-Induced Peripheral Neuropathy (QLQ-CIPN20), the Medicinae Doctor Anderson Symptom Inventory (MDASI), and a numeral rating scale (NRS). We also used the Beck Depression Inventory (BDI) to evaluate the patient's mood change after relieving the paresthesia. Results: After treatment, the symptoms were improved. Paresthesia decreased 80%p after Korean medicine treatment. Conclusions: According to this study, Korean traditional medicine can be an effective treatment for paresthesia in patients suffering from CIPN over 2 years.
Abstract
Objective: This study reports the effect of Korean traditional medicine on persistent chemotherapy-induced peripheral neuropathy (CIPN). Methods: The patient was treated with Korean traditional medicine that included acupuncture, moxibustion, and herbal medicine. The effectiveness of the treatment was evaluated by the Quality of Life Questionnaire-Core 30 (QLQ-C30), the Quality of Life Questionnaire Chemotherapy-Induced Peripheral Neuropathy (QLQ-CIPN20), the Medicinae Doctor Anderson Symptom Inventory (MDASI), and a numeral rating scale (NRS). We also used the Beck Depression Inventory (BDI) to evaluate the patient's mood change after relieving the paresthesia. Results: After treatment, the symptoms were improved. Paresthesia decreased 80%p after Korean medicine treatment. Conclusions: According to this study, Korean traditional medicine can be an effective treatment for paresthesia in patients suffering from CIPN over 2 years.
참고문헌 (23)
- "Cancer Incidence and Death Status"[URL]
- "5 year disease free survival rates"[URL]
- 우인숙, "항암제에 의한 말초 신경병증의 최신 지견", 대한내과학회지, 88(1), pp.35~37 (2015), 대한내과학회[DOI]
- Seretny M, "Incidence, prevalence, and predictors of chemotherapy-induced peripheral neuropathy : A systematic review and meta-analysis", PAIN, 155(12), pp.2461~2470 (2014)
- Park SB, "Chemotherapy-Induced Peripheral Neurotoxicity : A Critical Analysis", Cancer J Clin, 63(6), pp.419~437 (2013)
- Richardson PG, "Frequency, characteristics, and reversibility of peripheral neuropathy during treatment of advanced multiple myeloma with bortezomib", J Clin Oncol, 24(19), pp.3113~3120 (2006)
- Kerckhove N, "Long-Term Effects, Pathophysiological Mechanisms, and Risk Factors of Chemotherapy-Induced Peripheral Neuropathies : A Comprehensive Literature Review", Frontiers in Pharmacology, 8(86), pp.1~17 (2017)
- Fayers PM, "The EORTC QLQ-C30 Scoring Manual", pp.1~12 (2001), European Organisation for Research and Treatment of Cancer
- Smith EML, "Assessing patient-reported peripheral neuropathy : the reliability and validity of the European Organization for Research and Treatment of Cancer QLQ-CIPN20 Questionnaire", Quality of Life Research, 22(10), pp.2787~2799 (2013)
- Yun YH, "Validation Study of the Korean Version of the M. D. Anderson Symptom Inventory", J of Pain and Symptom Management, 31(4), pp.345~352 (2006)
- Lazaridou A, "Essentials of Pain Medicine", pp.39~46 (2018), Elsevier
- 윤서영, "효과적인 우울증 치료를 위한 임상평가도구", 대한정신약물학회지, 23(4), pp.136~146 (2012), 대한정신약물학회
- Leppert W, "Role of oxycodone and oxycodone", naloxone in cancer pain management, 2010, pp.62(4), 578~591
- Zajaczkowska R, "Mechanisms of Chemotherapy-Induced Peripheral Neuropathy", International J of Molecular Sciences, 20(6), pp.1451~1479 (2019)
- Jo KH, "Textbook of Korean Internal medicine of Cardiology and Neurology", pp.416~419 (2013), Koonja
- Kook YB, "Text Book of the Herbal Formula Study", pp.268~269 (2008), Yunglimsa
- Litscher G, "Changed skin blood perfusion in the fingertip following acupuncture needle introduction as evaluated by laser Doppler perfusion imaging", Lasers in medical science, 17(1), pp.19~25 (2002)
- Ma S, "Responses of nitric oxide synthase expression in the gracile nucleus to sciatic nerve injury in young and aged rats", Brain research, 855(1), pp.124~131 (2000)
- Ogawa K, "Efficacy of contact needle therapy for chemotherapy-induced peripheral neuropathy", Evidence-Based Complementary and Alternative Medicine, 2013, pp.928129~ (2013)
- Stubblefield MD, "NCCN task force report : management of neuropathy in cancer", J of the National Comprehensive Cancer Network, 7(5), pp.S1~S26 (2009)
- 김은혜, "항암화학요법 유발 말초신경병증에 대한 침치료의 효과 : 체계적 문헌고찰 및 메타 분석", 대한한방내과학회지, 41(3), pp.350~361 (2020), 대한한방내과학회[DOI]
- Lim YK, "Details of Meridians & Acupoints", pp.213~230 (2012), Jonglyeonamu
- Wang Y, "Effects of synchronous or asynchronous electroacupuncture stimulation with low versus high frequency on spinal opioid release and tail flick nociception", Exp Neurol, 192(1), pp.156~162 (2005)