마그네슘 티타네이트 표면의 조골세포 부착도와 분화
Osteoblast adhesion and differentiation on magnesium titanate surface
1
조회
0
다운로드
1
인용
0
참고문헌
초록
Abstract
The nature of the implant surface can directly influence cellular response, ultimately affecting the rate and quality of new bone tissue formation. The aim of this in vitro study was to investigate if human osteoblast-like cells, Saos-2, would respond differently when plated on disks of magnesium titanate and machined titanium. Magnesium titanate disks were prepared using Micro Arc Oxidation(MAO) methods. Control samples were machined commercially pure titanium disks. The cell adhesion, proliferation and differentiation were evaluated by measuring cell number, and alkaline phosphatase(ALPase) activity at 1 day and 6 day after plating on the titanium disks. Measurement of cell number and ALPase activity in Saos-2 cells at 1 day did not demonstrate any difference between machined titanium and magnesium titanate. When compared to machined titanium disks, the number of cells was reduced on the magnesium titanate disks at 6 day, while ALPase activity was more pronounced on the magnesium titanate. Enhanced differentiation of cells grown on magnesium titanate samples was indicated by decreased cell proliferation and increased ALPase activity.
참고문헌 (58)
- Hansson BO, "Osseointegrated implants in the treat- ment of the edentulous jaw Experience from a 10-year period", pp.7~127 (1977), nemark PI
- Swed Dent J 1983, "Aspect of surface physics on titanium implants" (1983)
- Lausmaa J, "Surface spectros- copic characterization of titanium implant materials", 45, pp.133~46 (1990)
- Olefjord I, "Surface analysis of four dental implant systems", 8, pp.32~40 (1993)
- Zitter H, "The electrochemical behaviour of metallic implant materials as indicator of their biocompatibility", 21, pp.881~96 (1987)
- Williams DF, "Corrosion of implant mate- rials", 6, pp.237~65 (1976)
- Solar RJ, "In vitro corrosion testing of titanium surgical implant alloys:an approach to understan- ding titanium release from implants", 13, pp.217~50 (1979)
- m I, "Physicoche- mical considerations of titanium as a biomaterial", pp.115~34 (1992)
- Johansson CB, "On tissue reactions to metal implants University of Gö" (1991)
- Hastings GW, "inert ceramic materials in medicine and dentistry Handbook of biomaterial pro- perties", pp.340~354 (1998)
- Deportet D, "Five to six-year results of a prospective clinical trial using the ENDOPORE dental implant and a man- dibular overdenture", 10, pp.95~102 (1999)
- Buser D, "Interface shear strength of titanium implants with a sandblasted and acid-etched surface:a biomecha- nical study in the maxilla of miniature pigs", 45, pp.75~83 (1999)
- Palmer RM, "A 5-year prospective study of astra single tooth implants Clin Oral Implants Res 2000", 11, pp.179~182 (2000)
- Testori T, "A prospective multicenter clinical study of the osseotite implant:four-year interim report", 16, pp.193~200 (2001)
- Bowers, "Opti- mization of surface micromorphology for enhanced psteoblast response in vitro", 7(3), pp.302~310 (1992)
- Kieswetter, "The role of implant surface characteristics in the healing of bone", 7(4), pp.329~345 (1996)
- Lohmann, "Surface roughness modulates the response of MG63 osteo- blast-like cells to 1 through regulation of phospholipase A activity and activation of protein kinase A", pp.25 139~151 (1999)
- Ericsson, "A histomorphometric evaluation of bone-to-implant contact on machine prepared and roughened tita- nium dental implants A pilot study in the dog", pp.202~206 (1994)
- Larsson, "Bone response to surface modified tita- nium implants studies on electropo- lished imlants with different oxide thicknesses and morphology", pp.1062~1074 (1994)
- A, "A 1-year follow up of implants of differing surface roughness placed in rabbit bone", 12(4), pp.486~494 (1997)
- Jansen JA, "Application of magnet- ron sputtering for producing ceramic coatings on implant materials", 4, pp.28~34 (1993)
- Ishizawa H, "Formation and characterization of anodic titanium oxide films", 29, pp.65~72 (1995)
- Ektessabi AM, "Ion beam processing of bio-ceramics", 99, pp.610~3 (1995)
- Campbell PA, "Vacuum plasma sprayed hydroxyapatite coatings on titanium alloy substrates:surface characteriza- tion and observation of dissolution pro- cesses using atomic force microscopy", 14, pp.1167~72 (1996)
- Haddow DB, "gel derived calcium phosphate coa- tings for biomedical applications", 13, pp.261~5 (1998)
- Burgess AV, "in vitro characterization and com- parison to other plasma-sprayed hydro- xylapatite coatings", 10, pp.245~1 56 (1999)
- Lo WJ, "and biological characterization of pulsed laser deposited and plasma sputtered hydroxyapatite thin films on titanium alloy", 50, pp.536~45 (2000)
- Hench LL, "Properties of bioactive glasses and glassceramics Handbook of biomaterial properties Handbook of biomaterial properties", pp.355~63 (1998)
- Gottlander M, "On hard tissue reactions to hydroxyapatite-coated titanium im- plants Department of Biomaterials", Handicap Research Uni- versity of G, 1994, ~
- Albrektsson T, "Hydroxyapatite-coated implants:a case against their use", 56, pp.1312~26 (1998)
- Ong JL, "Hydroxyapatite and their use as coatings in dental im- plants:a review", 28, pp.667~707 (2000)
- Ishizawa H, "Mecha- nical and histological investigation of hydrothermally treated and untreated anodic titanium oxide.lms containing Ca and P", 29, pp.1459~68 (1995)
- Larsson C, "Bone response to surfacemodi studies on the tissue response after one year to machined and electropolished implants with different oxide thick- nesses", 8, pp.721~9 (1997)
- Hanawa T, "Early bone formation around calcium-ion-implanted titanium inserted into rat tibiae", 36, pp.131~6 (1997)
- Ichikawa T, "Three-dimensional bone response to commercially pure titanium and calcium-ion-mixing titanium in rabbits", 15, pp.231~8 (2000)
- Yan WQ, "Bonding of chemically treated titanium implants to bone", 37, pp.267~75 (1997)
- SkripitzR, "Tensile bond between bone and titanium", 69, pp.2~6 (1998)
- Fini M, "In vitro and vivo behaviour of Ca and P-enriched anodized titanium", 20, pp.1587~94 (1999)
- Nishiguchi S, "The effect of heat treatment on bone- bon- ding ability of alkali-treated titani- um", 20, pp.491~500 (1999)
- Henry P, "Removal torque comparison of TiUnite and turned implants in the Greyhound dog mandible", 1, pp.15~17 (2000)
- Albrektsson T, "Experimental studies on oxidized implants.A histo- morphometrical and biomechanical analysis", 1, pp.21~24 (2000)
- Sul YT, "The electrochemical oxide growth behaviour on titanium in acid and alkaline electrolytes", 23, pp.329~46 (2001)
- Sul YT, "Characteristics of the surface oxides on turned and electro- chemically oxidized pure titanium im- plants up to dielectric breakdown", pp.491~501
- Sul YT, "Reso- nance frequency and and removal torque analysis of implants with turned and anodized surface oxide", 13, pp.252~259 (2002)
- Sul YT, "Qualitative and quan- titative observations of bone tissue reactions to anodized implants", 23, pp.1809~19 (2002)
- Sul YT, "Oxi- dised implants and their influence on the bone response", 12, pp.1025~31 (2001)
- Sul YT, "Bone reactions to oxidized titanium implants with electro- chemically anion S and P incorporation", 4, pp.478~87 (2002)
- Sul YT, "Oxidized titanium screws coated with calcium ions and their performance in rabbit bone", 17, pp.625~634 (2002)
- Sul YT, "The significance of the surface properties of oxidized titanium to the bone response:special emphasis on potential biochemical bonding of oxi- dized titanium implant", 24, pp.3893~3907 (2003)
- Kwon, "Titanium particles inhibit osteoblast adhesion to fibronec- tin-coated substrates", 18(2), pp.203~211 (2000)
- Gailit J, "Regulation of the fibronectin receptor affinity by diva- lent cations", 263, pp.12927~12932 (1988)
- Mould AP, "Regulation of integrin alpha 5 beta 1-fibronectin interactions by divalent cations Evidence for distinct classes of binding sites for Mn2+", pp.26270~26277 (1995)
- Krause A, "Integrin-mediated signaling in osteo- blasts on titanium implant materials", 52(wicz g), pp.738~747 (2000)
- Cooper LF, "Generalizations regarding the process and phenomenon of osseo- integration", pp.163~74 (1998)
- Davies JE, "In vitro modeling of the bone", implant interface, 1996, pp.245, 426~45
- Owen TA, "Progressive development of the rat osteoblast phenotype in vitro:reciprocal relationships in expression of genes associated with osteoblast proli- feration and differentiation during for- mation of the bone extracellular matrix", 143, pp.420~30 (1990)
- Ali SY, "Mechanisms of calcification Scientific foundation of ortho- paedics and traumatology", pp.175~95 (1984), Heinemann
- Dean DD, "Matrix vesicles produced by osteo- blast-like cells in culture become signi- ficantly enriched in proteoglycandeg- rading metallo-proteinases after addi- tion of β-glycerophosphate and as- corbic acid", 54, pp.399~408 (1994)
