A preliminary report on histological outcome of pulpotomy with endodontic biomaterials vs calcium hydroxide
2
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
Objectives: The purpose of the study was to evaluate human dental pulp response topulpotomy with calcium hydroxide (CH), mineral trioxide aggregate (MTA), and calciumenriched mixture (CEM) cement. Materials and Methods: A total of nine erupted thirdmolars were randomly assigned to each pulpotomy group. The same clinician performedfull pulpotomies and coronal restorations. The patients were followed clinically forsix months; the teeth were then extracted and prepared for histological assessments. The samples were blindly assessed by an independent observer for pulp vitality, pulpinflammation, and calcified bridge formation. Results: All patients were free of clinicalsigns/symptoms of pulpal/periradicular diseases during the follow up period. In CHgroup, one tooth had necrotic radicular pulp; other two teeth in this group had vitaluninflamed pulps with complete dentinal bridge formation. In CEM cement and MTAgroups all teeth had vital uninflamed radicular pulps. A complete dentinal bridgewas formed beneath CEM cement and MTA in all roots. Odontoblast-like cells werepresent beneath CEM cement and MTA in all samples. Conclusions: This study revealedthat CEM cement and MTA were reliable endodontic biomaterials in full pulpotomytreatment. In contrast, the human dental pulp response to CH might be unpredictable.
Abstract
Objectives: The purpose of the study was to evaluate human dental pulp response topulpotomy with calcium hydroxide (CH), mineral trioxide aggregate (MTA), and calciumenriched mixture (CEM) cement. Materials and Methods: A total of nine erupted thirdmolars were randomly assigned to each pulpotomy group. The same clinician performedfull pulpotomies and coronal restorations. The patients were followed clinically forsix months; the teeth were then extracted and prepared for histological assessments. The samples were blindly assessed by an independent observer for pulp vitality, pulpinflammation, and calcified bridge formation. Results: All patients were free of clinicalsigns/symptoms of pulpal/periradicular diseases during the follow up period. In CHgroup, one tooth had necrotic radicular pulp; other two teeth in this group had vitaluninflamed pulps with complete dentinal bridge formation. In CEM cement and MTAgroups all teeth had vital uninflamed radicular pulps. A complete dentinal bridgewas formed beneath CEM cement and MTA in all roots. Odontoblast-like cells werepresent beneath CEM cement and MTA in all samples. Conclusions: This study revealedthat CEM cement and MTA were reliable endodontic biomaterials in full pulpotomytreatment. In contrast, the human dental pulp response to CH might be unpredictable.
참고문헌 (40)
- Kakehashi S, "The effects of surgical exposures of dental pulps in germ-free and conventional laboratory rats", Oral Surg Oral Med Oral Pathol, 20, pp.340~349 (1965)
- Witherspoon DE, "Vital pulp therapy with new materials: new directions and treatment perspectives-permanent teeth", J Endod, 34, pp.S25~S28 (2008)
- Tziafas D, "Designing new treatment strategies in vital pulp therapy", J Dent, 28, pp.77~92 (2000)
- Witherspoon DE, "Mineral trioxide aggregate pulpotomies: a case series outcomes assesment", J Am Dent Assoc, 137, pp.610~618 (2006)
- Nosrat IV, "Reparative hard tissue formation following calcium hydroxide application after partial pulpotomy in cariously exposed pulps of permanent teeth", Int Endod J, 31, pp.221~226 (1998)
- Costa CA, "Current status of pulp capping with dentin adhesive systems: a review", Dent Mater, 16, pp.188~197 (2000)
- Barrieshi-Nusair KM, "A prospective clinical study of mineral trioxide aggregate for partial pulpotomy in cariously exposed permanent teeth", J Endod, 32, pp.731~735 (2006)
- Ford TR, "Using mineral trioxide aggregate as a pulp-capping material", J Am Dent Assoc, 127, pp.1491~1494 (1996)
- Holland R, "Permeability of the hard tissue bridge formed after pulpotomy with calcium hydroxide: a histologic study", J Am Dent Assoc, 99, pp.472~475 (1979)
- Asgary S, "A comparative study of histologic response to different pulp capping materials and a novel endodontic cement", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 106, pp.609~614 (2008)
- Nair PN, "Histological, ultrastructural and quantitative investigations on the response of healthy human pulps to experimental capping with mineral trioxide aggregate: a randomized controlled trial", Int Endod J, 41, pp.128~150 (2008)
- Eghbal MJ, "MTA pulpotomy of human permanent molars with irreversible pulpitis", Aust Endod J, 35, pp.4~8 (2009)
- Chueh LH, "Histology of Irreversible pulpitis premolars treated with mineral trioxide aggregate pulpotomy", Oper Dent, 35, pp.370~374 (2010)
- 양원경, "Evaluation of the rat tissue reaction to experimental new resin cement and mineral trioxide aggregate cement", Restorative Dentistry and Endodontics, 37(4), pp.194~200 (2012), 대한치과보존학회
- Torabinejad M, "Mineral trioxide aggregate: a comprehensive literature review-part II: leakage and biocompatibility investigations", J Endod, 36, pp.190~202 (2010)
- Nosrat A, "Regenerative endodontic treatment (revascularization) for necrotic immature permanent molars: a review and report of two cases with a new biomaterial", J Endod, 37, pp.562~567 (2011)
- Asgary S, "Antibacterial effects of five different root canal sealing materials", J Oral Sci, 50, pp.469~474 (2008)
- Parirokh M, "Mineral trioxide aggregate: a comprehensive literature review-part III: clinical applications, drawbacks, and mechanism of action", J Endod, 36, pp.400~413 (2010)
- Asgary S, "Comparison of mineral trioxide aggregate’s composition with Portland cements and a new endodontic cement", J Endod, 35, pp.243~250 (2009)
- Asgary S, "The Properties of a New Endodontic Material", J Endod, 34, pp.990~993 (2008)
- Mozayeni MA, "Cytotoxicity of calcium enriched mixture cement compared with mineral trioxide aggregate and intermediate restorative material", Aust Endod J, 38, pp.70~75 (2012)
- Tabarsi B, "A comparative study of dental pulp response to several pulpotomy agents", Int Endod J, 43, pp.565~571 (2010)
- Asgary S, "Periapical healing after direct pulp capping with calcium-enriched mixture cement: a case report", Oper Dent, 37, pp.571~575 (2012)
- Parirokh M, "Comparative study of subcutaneous tissue responses to a novel root-end filling material and white and grey mineral trioxide aggregate", Int Endod J, 44, pp.283~289 (2011)
- Asgary S, "Sealing ability of a novel endodontic cement as a root-end filling material", J Biomed Mater Res A, 87, pp.706~709 (2008)
- Nosrat A, "Apexogenesis treatment with a new endodontic cement: a case report", J Endod, 36, pp.912~914 (2010)
- Asgary S, "Permanent molar pulpotomy with a new endodontic cement: a case series", J Conserv Dent, 12, pp.31~36 (2009)
- Nosrat A, "Apexogenesis of a symptomatic molar with calcium enriched mixture", Int Endod J, 43, pp.940~944 (2010)
- Nosrat A, "Pulpotomy in cariesexposed immature permanent molars using calciumenriched mixture cement or mineral trioxide aggregate: a randomized clinical trial", Int J Paediatr Dent, 23, pp.56~63 (2013)
- Asgary S, "Oneyear results of vital pulp therapy in permanent molars with irreversible pulpitis: an ongoing multicenter, randomized, non-inferiority clinical trial", Clin Oral Investig, 17, pp.431~439 (2013)
- Asgary S, "Treatment outcomes of pulpotomy in permanent molars with irreversible pulpitis using biomaterials: a multi-center randomized controlled trial", Acta Odontol Scand, 71, pp.130~136 (2013)
- Dominguez MS, "Histological and scanning electron microscopy assessment of various vital pulp-therapy materials", J Endod, 29, pp.324~333 (2003)
- Zarrabi MH, "Histologic assessment of human pulp response to capping with mineral trioxide aggregate and a novel endodontic cement", J Endod, 36, pp.1778~1781 (2010)
- Caliskan M, "Clinical reliability of the dentine bridge formed after pulpotomy: a case report", Int Endod J, 27, pp.52~55 (1994)
- Sarkar NK, "Physicochemical basis of the biologic properties of mineral trioxide aggregate", J Endod, 31, pp.97~100 (2005)
- Asgary S, "Effect of two storage solutions on surface topography of two root-end fillings", Aust Endod J, 35, pp.147~152 (2009)
- Barthel CR, "Pulp capping of carious exposures: treatment outcome after 5 and 10 years: a retrospective study", J Endod, 26, pp.525~528 (2000)
- Torabinejad M, "Physical and chemical properties of a new root-end filling material", J Endod, 21, pp.349~353 (1995)
- 장석우, "Chemical characteristics of mineral trioxide aggregate and its hydration reaction", Restorative Dentistry and Endodontics, 37(4), pp.188~193 (2012), 대한치과보존학회
- Alongi DJ, "Stem", progenitor cells from inflamed human dental pulp retain tissue regeneration potential, 2010, pp.5, 617~631