Alveolar socket preservation with demineralised bovine bone mineral and a collagen matrix
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초록
Purpose: The aim of the present study was to evaluate the healing of post-extraction sockets following alveolar ridge preservation clinically, radiologically, and histologically. Methods: Overall, 7 extraction sockets in 7 patients were grafted with demineralised bovine bone mineral and covered with a porcine-derived non-crosslinked collagen matrix (CM). Soft tissue healing was clinically evaluated on the basis of a specific healing index. Horizontal and vertical ridge dimensional changes were assessed clinically and radiographically at baseline and 6 months after implant placement. For histological and histomorphometric analysis, bone biopsies were harvested from the augmented sites during implant surgery 6 months after the socket preservation procedure. Results: Clinically, healing proceeded uneventfully in all the sockets. A trend towards reduced horizontal and vertical socket dimensions was observed from baseline to the final examination. The mean width and height of resorption were 1.21 mm (P=0.005) and 0.46 mm (P=0.004), respectively. Histologically, residual xenograft particles (31.97%±3.52%) were surrounded by either newly formed bone (16.02%±7.06%) or connective tissue (50.67%±8.42%) without fibrous encapsulation. The CM underwent a physiological substitution process in favour of well-vascularised collagen-rich connective tissue. Conclusions: Socket preservation using demineralised bovine bone mineral in combination with CM provided stable dimensional changes of the alveolar ridge associated with good re-epithelialisation of the soft tissues during a 6-month healing period.
Abstract
Purpose: The aim of the present study was to evaluate the healing of post-extraction sockets following alveolar ridge preservation clinically, radiologically, and histologically. Methods: Overall, 7 extraction sockets in 7 patients were grafted with demineralised bovine bone mineral and covered with a porcine-derived non-crosslinked collagen matrix (CM). Soft tissue healing was clinically evaluated on the basis of a specific healing index. Horizontal and vertical ridge dimensional changes were assessed clinically and radiographically at baseline and 6 months after implant placement. For histological and histomorphometric analysis, bone biopsies were harvested from the augmented sites during implant surgery 6 months after the socket preservation procedure. Results: Clinically, healing proceeded uneventfully in all the sockets. A trend towards reduced horizontal and vertical socket dimensions was observed from baseline to the final examination. The mean width and height of resorption were 1.21 mm (P=0.005) and 0.46 mm (P=0.004), respectively. Histologically, residual xenograft particles (31.97%±3.52%) were surrounded by either newly formed bone (16.02%±7.06%) or connective tissue (50.67%±8.42%) without fibrous encapsulation. The CM underwent a physiological substitution process in favour of well-vascularised collagen-rich connective tissue. Conclusions: Socket preservation using demineralised bovine bone mineral in combination with CM provided stable dimensional changes of the alveolar ridge associated with good re-epithelialisation of the soft tissues during a 6-month healing period.
참고문헌 (39)
- Tan WL, "A systematic review of post-extractional alveolar hard and soft tissue dimensional changes in humans", Clin Oral Implants Res, 23(Suppl 5), pp.1~21 (2012)
- Araújo MG, "Alveolar socket healing : what can we learn?", Periodontol 2000, 68, pp.122~134 (2015)
- Botticelli D, "Hard-tissue alterations following immediate implant placement in extraction sites", J Clin Periodontol, 31, pp.820~828 (2004)
- Laney WR, "Glossary of oral and maxillofacial implants" (2007), Quintessence
- Jambhekar S, "Clinical and histologic outcomes of socket grafting after flapless tooth extraction : a systematic review of randomized controlled clinical trials", J Prosthet Dent, 113, pp.371~382 (2015)
- Araújo MG, "Dynamics of Bio-Oss Collagen incorporation in fresh extraction wounds : an experimental study in the dog", Clin Oral Implants Res, 21, pp.55~64 (2010)
- Sbordone C, "Retrospective volume analysis of bone remodeling after tooth extraction with and without deproteinized bovine bone mineral insertion", Clin Oral Implants Res, 27, pp.1152~1159 (2016)
- Gross JS, "Bone grafting materials for dental applications : a practical guide", Compend Contin Educ Dent, 18, pp.1013~1018 (1997)
- Lindhe J, "Ridge preservation with the use of deproteinized bovine bone mineral", Clin Oral Implants Res, 25, pp.786~790 (2014)
- Cardaropoli D, "Relationship between the buccal bone plate thickness and the healing of postextraction sockets with", without ridge preservation, 2014, pp.34, 211~217
- Becker W, "Histologic findings after implantation and evaluation of different grafting materials and titanium micro screws into extraction sockets : case reports", J Periodontol, 69, pp.414~421 (1998)
- Carmagnola D, "Healing of human extraction sockets filled with Bio-Oss", Clin Oral Implants Res, 14, pp.137~143 (2003)
- Sisti A, "Clinical evaluation of a ridge augmentation procedure for the severely resorbed alveolar socket: multicenter randomized controlled trial, preliminary results", Clin Oral Implants Res, 23, pp.526~535 (2012)
- Avila-Ortiz G, "Effect of alveolar ridge preservation after tooth extraction : a systematic review and meta-analysis", J Dent Res, 93, pp.950~958 (2014)
- Ghanaati S, "Evaluation of the tissue reaction to a new bilayered collagen matrix in vivo and its translation to the clinic", Biomed Mater, 6, pp.015010~ (2011)
- Herford AS, "Use of a porcine collagen matrix as an alternative to autogenous tissue for grafting oral soft tissue defects", J Oral Maxillofac Surg, 68, pp.1463~1470 (2010)
- Sanz M, "Clinical evaluation of a new collagen matrix(Mucograft prototype)to enhance the width of keratinized tissue in patients with fixed prosthetic restorations : a randomized prospective clinical trial", J Clin Periodontol, 36, pp.868~876 (2009)
- Thoma DS, "Impact of a collagen matrix on early healing, aesthetics and patient morbidity in oral mucosal wounds - a randomized study in humans", J Clin Periodontol, 39, pp.157~165 (2012)
- Jung RE, "Local tolerance and efficiency of two prototype collagen matrices to increase the width of keratinized tissue", J Clin Periodontol, 38, pp.173~179 (2011)
- Parashis AO, "Prospective clinical and radiographic study of alveolar ridge preservation combining freeze-dried bone allograft with two xenogeneic collagen matrices", J Periodontol, 87, pp.416~425 (2016)
- Landsberg CJ, "Implementing socket seal surgery as a socket preservation technique for pontic site development : surgical steps revisited--a report of two cases", J Periodontol, 79, pp.945~954 (2008)
- Landry R, "Effectiveness of benzydamyne HCl in the treatment of periodontal post-surgical patients", Res Clin Forums, 10, pp.105~118 (1988)
- Donath K, "A method for the study of undecalcified bones and teeth with attached soft tissues. The Säge-Schliff (sawing and grinding) technique", J Oral Pathol, 11, pp.318~326 (1982)
- Morjaria KR, "Bone healing after tooth extraction with or without an intervention : a systematic review of randomized controlled trials", Clin Implant Dent Relat Res, 16, pp.1~20 (2014)
- Cardaropoli D, "Socket preservation using bovine bone mineral and collagen membrane : a randomized controlled clinical trial with histologic analysis", Int J Periodontics Restorative Dent, 32, pp.421~430 (2012)
- Darby I, "Ridge preservation techniques for implant therapy", Int J Oral Maxillofac Implants, 24(Suppl), pp.260~271 (2009)
- Willenbacher M, "The effects of alveolar ridge preservation : a meta-analysis", Clin Implant Dent Relat Res, 18, pp.1248~1268 (2016)
- Festa VM, "Porcine-derived xenograft combined with a soft cortical membrane versus extraction alone for implant site development : a clinical study in humans", Clin Implant Dent Relat Res, 15, pp.707~713 (2013)
- Nevins M, "A study of the fate of the buccal wall of extraction sockets of teeth with prominent roots", Int J Periodontics Restorative Dent, 26, pp.19~29 (2006)
- Chappuis V, "Ridge alterations post-extraction in the esthetic zone: a 3D analysis with CBCT", J Dent Res, 92, pp.195S~201S (2013)
- Meloni SM, "Postextraction socket preservation using epithelial connective tissue graft vs porcine collagen matrix. 1-year results of a randomised controlled trial", Eur J Oral Implantol, 8, pp.39~48 (2015)
- Hallman M, "Histologic analysis of clinical biopsies taken 6 months and 3 years after maxillary sinus floor augmentation with 80% bovine hydroxyapatite and 20% autogenous bone mixed with fibrin glue", Clin Implant Dent Relat Res, 3, pp.87~96 (2001)
- Sartori S, "Ten-year follow-up in a maxillary sinus augmentation using anorganic bovine bone (Bio-Oss). A case report with histomorphometric evaluation", Clin Oral Implants Res, 14, pp.369~372 (2003)
- De Risi V, "Alveolar ridge preservation techniques : a systematic review and meta-analysis of histological and histomorphometrical data", Clin Oral Implants Res, 26, pp.50~68 (2015)
- Lindgren C, "A 3-year clinical follow-up of implants placed in two different biomaterials used for sinus augmentation", Int J Oral Maxillofac Implants, 27, pp.1151~1162 (2012)
- Rocchietta I, "Soft tissue integration of a porcine collagen membrane : an experimental study in pigs", Int J Periodontics Restorative Dent, 32, pp.34~40 (2012)
- Jung RE, "Radiographic evaluation of different techniques for ridge preservation after tooth extraction : a randomized controlled clinical trial", J Clin Periodontol, 40, pp.90~98 (2013)
- Perelman-Karmon M, "Socket site preservation using bovine bone mineral with and without a bioresorbable collagen membrane", Int J Periodontics Restorative Dent, 32, pp.459~465 (2012)
- Roccuzzo M, "Long-term stability of soft tissues following alveolar ridge preservation : 10-year results of a prospective study around nonsubmerged implants", Int J Periodontics Restorative Dent, 34, pp.795~804 (2014)