Oncocytic Type Intraductal Papillary Mucinous Neoplasm Mimicking Mucinous Cystic Neoplasm of the Pancreas - A Case Report -
0
조회
0
다운로드
0
인용
0
참고문헌
초록
Oncocytic type intraductal papillary mucinous neoplasm is a newly defined subgroup of intraductal papillary mucinous neoplasms. A 35-year-old woman presented complaining of epigastric pain for one month. Enhanced computed tomography revealed a multilocular cystic mass in the distal body and tail of the pancreas. Endoscopic retrograde cholangiopancreatography showed no communication between the mass and the main pancreatic duct. The patient underwent a distal pancreatectomy and splenectomy. Microscopical examination showed a fibrous cyst wall; polypoid tumors exhibiting thin stalks, with extensive arborizing papillary growths from these stalks; and a focally cribriform pattern, lined by plump cells with abundant eosinophilic and granular cytoplasm. Red granules were detected in the cytoplasm of tumor cells on modified Gomori trichrome stain. Ultrastructurally, the tumor cells contained abundant cytoplasm packed with numerous mitochondria and intracellular and intercellular lumina. We describe an oncocytic type intraductal papillary mucinous neoplasm having the clinical characteristics of a mucinous cystic neoplasm.
Abstract
Oncocytic type intraductal papillary mucinous neoplasm is a newly defined subgroup of intraductal papillary mucinous neoplasms. A 35-year-old woman presented complaining of epigastric pain for one month. Enhanced computed tomography revealed a multilocular cystic mass in the distal body and tail of the pancreas. Endoscopic retrograde cholangiopancreatography showed no communication between the mass and the main pancreatic duct. The patient underwent a distal pancreatectomy and splenectomy. Microscopical examination showed a fibrous cyst wall; polypoid tumors exhibiting thin stalks, with extensive arborizing papillary growths from these stalks; and a focally cribriform pattern, lined by plump cells with abundant eosinophilic and granular cytoplasm. Red granules were detected in the cytoplasm of tumor cells on modified Gomori trichrome stain. Ultrastructurally, the tumor cells contained abundant cytoplasm packed with numerous mitochondria and intracellular and intercellular lumina. We describe an oncocytic type intraductal papillary mucinous neoplasm having the clinical characteristics of a mucinous cystic neoplasm.
참고문헌 (10)
- Longnecker DS, "Intraductal papillary mucinous neoplasms of the pancreas", WHO Classification of Tumours of the Digestive System, 237~240 (2000)
- Jyotheeswaran S, "A newly recognized entity: intraductal ‘‘oncocytic’’ papillary neoplasm of the pancreas", Am J Gastroenterol, 93, pp.2539~2543 (1998)
- Tallini G, "Oncocytic tumours", Virchows Arch, 433, pp.5~12 (1998)
- Adsay NV, "Intraductal oncocytic papillary neoplasms of the pancreas", Am J Surg Pathol, 20, pp.980~994 (1996)
- Furukawa T, "Classification of types of intraductal papillary-mucinous neoplasm of the pancreas: a consensus study", Virchows Arch, 447, pp.794~799 (2005)
- Bondeson L, "Oncocytic tumor of the pancreas. Report of a case with aspiration cytology", Acta Cytol, 34, pp.425~428 (1990)
- Radi MJ, "Functioning oncocytic islet-cell carcinoma", Am J Surg Pathol, 9, pp.517~524 (1985)
- Lee WY, "Papillary cystic tumor of the pancreas: a case indistinguishable from oncocytic carcinoma", Pancreas, 8, pp.127~132 (1993)
- Shima Y, "Intraductal oncocytic papillary neoplasm of the pancreas with celiac artery compression syndrome and a jejunal artery aneurysm: report of a case", Surg Today, 35, pp.86~90 (2005)
- Oku T, "Intraductal oncocytic papillary neoplasm having clinical characteristics of mucinous cystic neoplasm and a benign histology", J Pancreas, 8, pp.206~213 (2007)