췌관내 유두상점액종양의 임상적 특징 및 예후
Clinical Features and Prognosis of Intraductal Papillary Mucinous Neoplasm of the Pancreas
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초록
Intraductal papillary mucinous neoplasm is frequently found recently and have recognized as precancerous lesions to pancreaticcancer that characterized by papillary growth of the ductal epithelium with rich mucin production and cystic dilatation of the mainpancreatic duct and/or its branches. These tumors are asymptomatic and often multifocal. Preoperative differentiation betweenbenign and malignant lesions is important to select the most appropriate treatment and to improve prognosis. Surgical resection isthe treatment of choice to avoid malignant transformation when predictive factors for malignancy are present. These factors includemural nodule in the cyst, main pancreatic duct dilation, thick septum, cyst greater than 3 cm, atypias in the cyst fluid and thepresence of symptoms. The follow-up of these patients who do not undergo surgical resection, is of great importance, since patientswith IPMN appear to be at risk for pancreatic cancer. Patients who retain a portion of their pancreas following resection of an IPMNneed to be followed up with periodic imaging to detect recurrences and metachronous lesions.
Abstract
Intraductal papillary mucinous neoplasm is frequently found recently and have recognized as precancerous lesions to pancreaticcancer that characterized by papillary growth of the ductal epithelium with rich mucin production and cystic dilatation of the mainpancreatic duct and/or its branches. These tumors are asymptomatic and often multifocal. Preoperative differentiation betweenbenign and malignant lesions is important to select the most appropriate treatment and to improve prognosis. Surgical resection isthe treatment of choice to avoid malignant transformation when predictive factors for malignancy are present. These factors includemural nodule in the cyst, main pancreatic duct dilation, thick septum, cyst greater than 3 cm, atypias in the cyst fluid and thepresence of symptoms. The follow-up of these patients who do not undergo surgical resection, is of great importance, since patientswith IPMN appear to be at risk for pancreatic cancer. Patients who retain a portion of their pancreas following resection of an IPMNneed to be followed up with periodic imaging to detect recurrences and metachronous lesions.
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