Intraductal Papillary Mucinous Tumor Simultaneously Involving the Liver and Pancreas - A Case Report -
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We describe here a 67-year-old man who was diagnosed with a rare case of intraductal papillary mucinous tumors that occurred simultaneously in the liver and pancreas. Abdominal computed tomography showed a tubular and cystic dilatation of the pancreatic duct in the pancreas tail, which suggested an intraductal papillary mucinous tumor (IPMT), and multiple intrahepatic duct stones. The patient underwent a distal pancreatectomy with splenectomy and a lateral segmentectomy of the liver. Microscopic examination showed an intraductal papillary mucinous neoplasms of borderline malignancy in the pancreas and a non-invasive intraductal papillary mucinous tumor with moderate dysplasia of the bile duct. Although several cases of intraductal papillary mucinous neoplasm of the liver (IPNL) without any pancreatic association have been described, the simultaneous presentation of both IPMT of the pancreas and IPNL is very rare. The patient has been doing well for 10 months postoperatively.
Abstract
We describe here a 67-year-old man who was diagnosed with a rare case of intraductal papillary mucinous tumors that occurred simultaneously in the liver and pancreas. Abdominal computed tomography showed a tubular and cystic dilatation of the pancreatic duct in the pancreas tail, which suggested an intraductal papillary mucinous tumor (IPMT), and multiple intrahepatic duct stones. The patient underwent a distal pancreatectomy with splenectomy and a lateral segmentectomy of the liver. Microscopic examination showed an intraductal papillary mucinous neoplasms of borderline malignancy in the pancreas and a non-invasive intraductal papillary mucinous tumor with moderate dysplasia of the bile duct. Although several cases of intraductal papillary mucinous neoplasm of the liver (IPNL) without any pancreatic association have been described, the simultaneous presentation of both IPMT of the pancreas and IPNL is very rare. The patient has been doing well for 10 months postoperatively.
참고문헌 (13)
- Fitzgerald TL, "Changing incidence of pancreatic neoplasms:a 16-year review of statewide tumor registry", Pancreas, 37, pp.134~138 (2008)
- Edirimanne S, "Incidental pancreatic cystic lesions", World J Surg, 32, pp.2028~2037 (2008)
- Riall TS, "Incidence of additional primary cancers in patients with invasive intraductal papillary mucinous neoplasms and sporadic pancreatic adenocarcinomas", J Am Coll Surg, 204, pp.803~813 (2007)
- Kim HJ, "Mucin-hypersecreting bile duct tumor characterized by a striking homology with an intraductal papillary mucinous tumor(IPMT)of the pancreas", Endoscopy, 32, pp.389~393 (2000)
- Chen TC, "Intraductal papillary neoplasia of the liver associated with hepatolithiasis", Hepatology, 34, pp.651~658 (2001)
- Paik KY, "Intraductal papillary neoplasm of the bile ducts:the clinical features and surgical outcome of 25 cases", J Surg Oncol, 97, pp.508~512 (2008)
- Tanaka M, "Clinical aspects of intraductal papillary mucinous neoplasm of the pancreas", J Gastroenterol, 40, pp.669~675 (2005)
- Joo YH, "A case of mucin-hypersecreting intrahepatic bile duct tumor associated with pancreatic intraductal papillary mucinous tumor", Gastrointest Endosc, 52, pp.409~412 (2000)
- Ishida M, "Intraductal mucinous tumors occurring simultaneously in the liver and pancreas", J Gastroenterol, 37, pp.1073~1078 (2002)
- Yamaguchi Y, "A case of mucin hypersecreting intraductal papillary carcinomas occurring simultaneously in liver and pancreas", Gastrointest Endosc, 61, pp.330~334 (2005)
- Iacobuzio-Donahue CA, "Dpc-4 protein is expressed in virtually all human intraductal papillary mucinous neoplasms of the pancreas:comparison with conventional ductal adenocarcinomas", Am J Pathol, 157, pp.755~761 (2000)
- Tada M, "Analysis of K-ras gene mutation in hyperplastic duct cells of the pancreas without pancreatic disease", Gastroenterology, 110, pp.227~231 (1996)
- Abraham SC, "Molecular and immunohistochemical analysis of intraductal papillary neoplasms of the biliary tract", Hum Pathol, 34, pp.902~910 (2003)