가토 두개골에 이식한 다양한 형태의 자가골에 의한 골성 회복 양상 비교 평가
A comparative study of various type of autogeneous bone graft on the rabbit-skull defect healing
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Introduction: Piezosurgery device is one of the most commonly used instrument on the intraoral surgery such as maxillary sinus lift and autogeneous bone graft. Piezosurgery instrument also contains the tips that are manufactured especially for the convenient bone graft, which now many surgeons apply them for collecting bone graft materials in the curettage method for the restoration of skull defects. However, objective data has not been shown concerning the effects about bone graft with using Piezosurgery. Therefore we investigated the effects of Piezosurgery on the rabbit-skull defect healing. Materials & Methods: To investigate the regeneration of the bony defect with various bone graft, 10 adult New Zealand white rabbits (average weight : 2.8 ± 0.3kg, about 12weeks) were used. The four circular bony defects measuring 6mm in diameter were made with Piezosurgery device on each rabbit cranial bone. The harvested bone tissues during defect formation were also used for autogeneous bone graft. They were grafted into the defects in a various type; block type (Group 1), particulated type by the bone mill (Group 2), chopped type by curette shaped Piezosurgery tip (Group 3), the defect without any graft was served as control (control group). The animals were sacrificed after 6 weeks and bone regeneration capacity was evaluated histomorphometrically. Result & Conclusion: Autogeneous bone graft harvested using a Piezosurgery instrument showed satisfactory bone regeneration. There was no conspicuous difference bone prepared amomg by bone mill or Piezosurgery and block bone graft. Therefore, the bone harvested from the intraoral site near the operation field using the piezosurgery device can be a feasible and reliable graft for intraoral bony defects.
Abstract
Introduction: Piezosurgery device is one of the most commonly used instrument on the intraoral surgery such as maxillary sinus lift and autogeneous bone graft. Piezosurgery instrument also contains the tips that are manufactured especially for the convenient bone graft, which now many surgeons apply them for collecting bone graft materials in the curettage method for the restoration of skull defects. However, objective data has not been shown concerning the effects about bone graft with using Piezosurgery. Therefore we investigated the effects of Piezosurgery on the rabbit-skull defect healing. Materials & Methods: To investigate the regeneration of the bony defect with various bone graft, 10 adult New Zealand white rabbits (average weight : 2.8 ± 0.3kg, about 12weeks) were used. The four circular bony defects measuring 6mm in diameter were made with Piezosurgery device on each rabbit cranial bone. The harvested bone tissues during defect formation were also used for autogeneous bone graft. They were grafted into the defects in a various type; block type (Group 1), particulated type by the bone mill (Group 2), chopped type by curette shaped Piezosurgery tip (Group 3), the defect without any graft was served as control (control group). The animals were sacrificed after 6 weeks and bone regeneration capacity was evaluated histomorphometrically. Result & Conclusion: Autogeneous bone graft harvested using a Piezosurgery instrument showed satisfactory bone regeneration. There was no conspicuous difference bone prepared amomg by bone mill or Piezosurgery and block bone graft. Therefore, the bone harvested from the intraoral site near the operation field using the piezosurgery device can be a feasible and reliable graft for intraoral bony defects.
참고문헌 (30)
- Hopp SG, "A study of the mechanical strength of long bone defects treated with various bone autograft substitutes : An experimental investigation in the rabbit", J Orthop Res, 7, pp.579~584 (1989)
- Goldberg VM, "Nature history of autograft and allograft", Clin Orthop, 7, pp.225~ (1987)
- Arrington ED, "Complications of iliac crest bone graft harvesting", Clin Orthop, 329, pp.300~309 (1996)
- Mulliken JB, "Application of demineralized allogenic bone implants for the correction of maxillocranial facial deformities", Ann Surg, 3, pp.633~ (1981)
- Kainulainen V, "Comparison of four bone collectors designed for oral and maxillofacial surgery : An in vitro study", Clin Oral Implants Res, 9, pp.327~324 (1998)
- Hoigne DJ, "Piezoelectric osteotomy in hand surgery: First experiences with a new technique", BMC Musculoskeletal Disorders, 7, pp.36~ (2006)
- Stubinger S, "Intraoral Piezosurgery : Preliminary results of a new technique", J Oral Maxillofac Surg, 63, pp.1283~1287 (2005)
- Akita S, "Cranial bone defect healing is accelerated by mesenchymal stem cells induced by coadministration of bone morphogenetic protein-2 and basic fibroblast growth factor", Wound Repair Regen, 12, pp.252~259 (2004)
- Sohn DS, "Piezoelectric osteotomy for intraoral harvesting of bone blocks", Int J Periodontics Restorative Dent, 27, pp.127~131 (2007)
- Siervo S, "Piezoelectric surgery. : An alternative method of minimally invasive surgery", Schweiz Monatsschr Zahnmed, 114, pp.365~377 (2004)
- Chiriac G, "Autogenous bone chips: Influence of a new piezoelectric device (Piezosurgery) on chip morphology, cell viability and differentiation", J Clin Periodontol, 32, pp.994~999 (2005)
- Urist MR, "The bone induction principle", Clin Orthop Relat Res, 53, pp.243~ (1967)
- Rivault AF, "Autogenous bone grafts : Osseous coagulum and osseous retrograde procedures in primates", J Periodontol, 42, pp.787~796 (1971)
- Jonk LM, "bone induction effect of fine bone shavings in polyester fiber", An experimental study. S Afr Med J, 49, pp.697~702 (1975)
- Shapoff CA, "The effect of particle size on the osteogenic activity of composite grafts of allogeneic freeze-dried bone and autogenous marrow", J Periodontol, 51, pp.625~630 (1980)
- Pallesen L, "Influence of particle size of autogenous bone grafts on the early stages of bone regeneration: A histologic and stereologic study in rabbit calvarium", Int J Oral Maxillofac Implants, 17, pp.498~506 (2002)
- Sivolella S, "Autogenous particulate bone collected with a Piezo-electric surgical device and bone trap: A microbiological and histomorphometric study", Arch Oral Biol, 51, pp.883~891 (2006)
- Schepers EJ, "Bioactive glass particles of narrow size range for the treatment of oral bone defects : A 1-24 month experiment with several materials and particle sizes and size ranges", J Oral Rehabil, 24, pp.171~181 (1997)
- Xu H, "Experimental sinus grafting with the use of deproteinized bone particles of different sizes", Clin Oral Impl Res, 14, pp.548~555 (2003)
- Shand JM, "Allogeneic bone grafting of calvarial defects: An experimental study in the rabbit", Int J Oral Maxillofac Surg, 31, pp.525~531 (2002)
- Haddad AJ, "Closure of rabbit calvarial critical-sized defects using protective composite allogeneic and alloplastic bone substitutes", J Craniofac Surg, 17, pp.926~934 (2006)
- Robiony M, "Piezoelectric bone cutting in multipiece maxillary osteotomies", J Oral Maxillofac Surg, 62, pp.759~761 (2004)
- Moghadam HG, "Histomorphometric evaluation of bone regeneration using allogeneic and alloplastic bone substitutes", J Oral Maxillofac Surg, 62, pp.202~213 (2004)
- Stal S, "Compartmentalized bone regeneration of cranial defects with biodegradable barriers : An animal model", J Craniofac Surg, 12, pp.41~47 (2001)
- Young MP, "Carter DH: bone collected during dental implant surgery : A clinical and histological study", Clin Oral Implants Res, 13, pp.298~303 (2002)
- Oikarinen K, "A method of harvesting corticocancellous bone chips for reconstructive maxillofacial surgery", Int J Oral Maxillofac Surg, 26, pp.103~105 (1997)
- Schlee M, "Piezosurgery basics and possibilities", Implant Dent, 15, pp.334~340 (2006)
- Lambrecht JT, "Intraoral piezo-surgery", Schweiz Monatsschr Zahnmed, 114, pp.28~36 (2004)
- Vercellotti T, "A new bone surgery device: Sinus grafting and periodontal surgery", Compend Contin Educ Dent, 27, pp.319~325 (2006)
- Clokie CM, "Closure of critical sized defects with allogenic and alloplastic bone substitutes", J Craniofac Surg, 13, pp.111~121 (2002)