Factors to consider for surgical in elderly patients with oral cancer
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
At present, in Korea, due to developments in medicine and technology and an increasing mean lifespan, the expected lifetime for elderly people is increasing (at 70 years, the expected additional lifespan is 14.8 years for males and 18.3 years for females). However, among all causes of death, ma-lignant neoplasm is ranked first for all ages. Further, the incidence rate of oral cancer tends to increase with age. Thus, oral and maxillofacial surgeons have increased opportunity to experience the ‘oldest old’ patients with oral cancer. Elderly patients commonly have several comorbidities, poor general condition, limited socioeconomic support, fear of various postoperative complications, and perception of short for the rest of their life. In this situa-tion, the patient, caregiver, and surgeon often choose undergraded treatment rather than standard treatment for oral squamous cell carcinoma owing to patient age. In elderly patients with oral cancer, ablation of tumor or reconstructive surgery is challenging for surgeons. Oral and maxillofacial surgeons must evaluate carefully the patient’s medical condition and make a decision regarding treatment plans after sufficient discussion with patient and care-givers. We review the literature to consider the factors involved for deciding on a treatment plan regarding surgery in elderly patients with oral cancer.
Abstract
At present, in Korea, due to developments in medicine and technology and an increasing mean lifespan, the expected lifetime for elderly people is increasing (at 70 years, the expected additional lifespan is 14.8 years for males and 18.3 years for females). However, among all causes of death, ma-lignant neoplasm is ranked first for all ages. Further, the incidence rate of oral cancer tends to increase with age. Thus, oral and maxillofacial surgeons have increased opportunity to experience the ‘oldest old’ patients with oral cancer. Elderly patients commonly have several comorbidities, poor general condition, limited socioeconomic support, fear of various postoperative complications, and perception of short for the rest of their life. In this situa-tion, the patient, caregiver, and surgeon often choose undergraded treatment rather than standard treatment for oral squamous cell carcinoma owing to patient age. In elderly patients with oral cancer, ablation of tumor or reconstructive surgery is challenging for surgeons. Oral and maxillofacial surgeons must evaluate carefully the patient’s medical condition and make a decision regarding treatment plans after sufficient discussion with patient and care-givers. We review the literature to consider the factors involved for deciding on a treatment plan regarding surgery in elderly patients with oral cancer.
참고문헌 (37)
- "Death rates for the 10 leading causes of death by age"[URL]
- Charlotte Rotbøl Bøje, "The impact of comorbidity on outcome in 12 623 Danish Head and Neck Cancer Patients: A population based study from the DAHANCA database", Acta Oncologica, 52(2), pp.285~293 (2013), Informa UK Limited[DOI]
- Ronald C. Chen, "Impact of Age and Comorbidity on Treatment and Outcomes in Elderly Cancer Patients", Seminars in Radiation Oncology, 22(4), pp.265~271 (2012), Elsevier BV[DOI]
- Qi-Gen Fang, "Free Flap Reconstruction Versus Non–Free Flap Reconstruction in Treating Elderly Patients With Advanced Oral Cancer", Journal of Oral and Maxillofacial Surgery, 72(7), pp.1420~1424 (2014), Elsevier BV[DOI]
- T. Sasaki, "Clinico-pathological features of squamous cell carcinoma of the oral cavity in patients <40 years of age", Journal of Oral Pathology and Medicine, 34(3), pp.129~133 (2005), Wiley[DOI]
- "Cancer incident cases and incidence rates by site (24 items), sex, age group"[URL]
- S. L. Parker, "Cancer statistics, 1997", CA: A Cancer Journal for Clinicians, 47(1), pp.5~27 (1997), Wiley[DOI]
- Ian S. Fentiman, "Are the elderly receiving appropriate treatment for cancer?", Annals of Oncology, 7(7), pp.657~658 (1996), Elsevier BV[DOI]
- Gary L. Clayman, "Surgical outcomes in head and neck cancer patients 80 years of age and older", Head & Neck, 20(3), pp.216~223 (1998), Wiley[DOI]
- Laetitia Gambotti, "Are elderly patients presenting with squamous cell carcinoma of the oral cavity given the appropriate treatment?", Surgical Oncology, 27(4), pp.715~721 (2018), Elsevier BV[DOI]
- Jay F. Piccirillo, "Comorbidity in patients with cancer of the head and neck: Prevalence and impact on treatment and prognosis", Current Oncology Reports, 8(2), pp.123~129 (2006), Springer Science and Business Media LLC[DOI]
- Britt C. Reid, "Comorbidity and survival of elderly head and neck carcinoma patients", Cancer, 92(8), pp.2109~2116 (2001), Wiley[DOI]
- Alvaro Sanabria, "Comorbidity Is a Prognostic Factor in Elderly Patients with Head and Neck Cancer", Annals of Surgical Oncology, 14(4), pp.1449~1457 (2007), Springer Science and Business Media LLC[DOI]
- Y. Wu, "Study of surgical treatment for elderly patients with head and neck cancer", International Journal of Oral and Maxillofacial Surgery, 47(7), pp.824~829 (2018), Elsevier BV[DOI]
- Jay F. Piccirillo, "Prognostic Importance of Comorbidity in a Hospital-Based Cancer Registry", JAMA, 291(20), pp.2441~ (2004), American Medical Association (AMA)[DOI]
- Marciano B. Ferrier, "Comorbidity as a Major Risk Factor for Mortality and Complications in Head and Neck Surgery", Archives of Otolaryngology–Head & Neck Surgery, 131(1), pp.27~ (2005), American Medical Association (AMA)[DOI]
- W. Derks, "Elderly patients with head and neck cancer: short-term effects of surgical treatment on quality of life", Clinical Otolaryngology and Allied Sciences, 28(5), pp.399~405 (2003), Wiley[DOI]
- Jie Jane Chen, "Clinical Outcomes in Elderly Patients Treated for Oral Cavity Squamous Cell Carcinoma", International Journal of Radiation Oncology*Biology*Physics, 98(4), pp.775~783 (2017), Elsevier BV[DOI]
- O BIRIM, "Charlson comorbidity index as a predictor of long-term outcome after surgery for nonsmall cell lung cancer", European Journal of Cardio-Thoracic Surgery, 28(5), pp.759~762 (2005), Oxford University Press (OUP)[DOI]
- Chun-Ming Chang, "Adjusted Age-Adjusted Charlson Comorbidity Index Score as a Risk Measure of Perioperative Mortality before Cancer Surgery", PLOS ONE, 11(2), pp.e0148076~ (2016), Public Library of Science (PLoS)[DOI]
- Suzuki H, "The Charlson comorbidity index is a prognostic factor in sinonasal tract squamous cell carcinoma", Jpn J Clin Oncol, 46, pp.646~651 (2016)[DOI]
- Mary E. Charlson, "A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation", Journal of Chronic Diseases, 40(5), pp.373~383 (1987), Elsevier BV[DOI]
- B Colinet, "A new simplified comorbidity score as a prognostic factor in non-small-cell lung cancer patients: description and comparison with the Charlson's index", British Journal of Cancer, 93(10), pp.1098~1105 (2005), Springer Science and Business Media LLC[DOI]
- Michael L. Volk, "Modified Charlson Comorbidity Index for predicting survival after liver transplantation", Liver Transplantation, 13(11), pp.1515~1520 (2007), Wiley[DOI]
- Molly E. Roseland, "Racial differences in breast cancer survival in a large urban integrated health system", Cancer, 121(20), pp.3668~3675 (2015), Wiley[DOI]
- Charlotte Rotbøl Bøje, "Evaluation of comorbidity in 9388 head and neck cancer patients: A national cohort study from the DAHANCA database", Radiotherapy and Oncology, 110(1), pp.91~97 (2014), Elsevier BV[DOI]
- Audisio RA, "Shall we operate? Preoperative assessment in elderly cancer patients (PACE) can help", Critical Reviews in Oncology, 2008, pp.65(2), 156~163[DOI]
- Lazzaro Repetto, "Comprehensive Geriatric Assessment Adds Information to Eastern Cooperative Oncology Group Performance Status in Elderly Cancer Patients: An Italian Group for Geriatric Oncology Study", Journal of Clinical Oncology, 20(2), pp.494~502 (2002), American Society of Clinical Oncology (ASCO)[DOI]
- "ECOG Performance Status"[URL]
- Yi-Shing Leu, "Squamous Cell Carcinoma of the Oral Cavity in the Elderly", International Journal of Gerontology, 3(1), pp.75~80 (2009), Airiti Press, Inc.[DOI]
- S. Ferrari, "Free flaps in elderly patients: Outcomes and complications in head and neck reconstruction after oncological resection", Journal of Cranio-Maxillofacial Surgery, 41(2), pp.167~171 (2013), Elsevier BV[DOI]
- Chia-Hsuan Tsai, "Postoperative morbidity in head and neck cancer ablative surgery followed by microsurgical free tissue transfer in the elderly", Oral Oncology, 48(9), pp.811~816 (2012), Elsevier BV[DOI]
- Thomas T.A. Peters, "Co-morbidity and treatment outcomes of elderly pharyngeal cancer patients: A matched control study", Oral Oncology, 47(12), pp.1159~1164 (2011), Elsevier BV[DOI]
- Thomas T. A. Peters, "Relation Between Age, Comorbidity, and Complications in Patients Undergoing Major Surgery for Head and Neck Cancer", Annals of Surgical Oncology, 21(3), pp.963~970 (2014), Springer Science and Business Media LLC[DOI]
- Jerome Sarini, "Head and Neck Squamous Cell Carcinoma in Elderly Patients", Archives of Otolaryngology–Head & Neck Surgery, 127(9), pp.1089~ (2001), American Medical Association (AMA)[DOI]
- Yong Han Kim, "Risk factors for competing non-cancer mortality after definitive treatment for advanced-stage head and neck cancer", Oral Diseases, 24(7), pp.1217~1225 (2018), Wiley[DOI]
- R. Yang, "Head and neck cancer surgery in an elderly patient population: a retrospective review", International Journal of Oral and Maxillofacial Surgery, 43(12), pp.1413~1417 (2014), Elsevier BV[DOI]