본문 바로가기
KERD
논문KCI 등재

Is two-dimensional echocardiography better than electrocardiography for predicting patient outcomes after cardiac arrest?

2

조회

0

다운로드

0

인용

0

참고문헌

키워드

초록

Background: Coronary artery stenosis increases hospital mortality and leads to poor neurologicalrecovery in cardiac arrest (CA) patients. However, electrocardiography (ECG) cannotfully predict the presence of coronary artery stenosis in CA patients. Hence, we aimed to determinewhether regional wall motion abnormality (RWMA), as observed by two-dimensionalechocardiography (2DE), predicted patient survival outcomes with greater accuracy than didST segment elevation (STE) on ECG in CA patients who underwent coronary angiography(CAG) after return of spontaneous circulation. Methods: This was a retrospective observational study of adult patients with CA of presumedcardiac etiology who underwent CAG at a single tertiary care hospital. We investigatedwhether RWMA observed on 2DE predicted patient outcomes more accurately than did STEobserved on ECG. The primary outcome was incidence of hospital mortality. The secondaryoutcomes were Glasgow-Pittsburgh Cerebral Performance Category scores measured 6months after discharge and significant coronary artery stenosis on CAG. Results: Among the 145 patients, 36 (24.8%) experienced in-hospital death. In multivariableanalysis of survival outcomes, only total arrest time (P=0.011) and STE (P=0.035) were significant. The odds ratio (OR) and 95% confidence interval (CI), which were obtained by adjustingthe total arrest time for survival outcomes, were significant only for STE (OR, 0.40;95% CI, 0.17–0.94). The presence of RWMA was not a significant factor. Conclusions: While STE predicted survival outcomes in adult CA patients, RWMA did not. Thedecision to perform CAG after CA should include ECG under existing guidelines. The use ofRWMA has limited benefits in treatment of this population.

Abstract

Background: Coronary artery stenosis increases hospital mortality and leads to poor neurologicalrecovery in cardiac arrest (CA) patients. However, electrocardiography (ECG) cannotfully predict the presence of coronary artery stenosis in CA patients. Hence, we aimed to determinewhether regional wall motion abnormality (RWMA), as observed by two-dimensionalechocardiography (2DE), predicted patient survival outcomes with greater accuracy than didST segment elevation (STE) on ECG in CA patients who underwent coronary angiography(CAG) after return of spontaneous circulation. Methods: This was a retrospective observational study of adult patients with CA of presumedcardiac etiology who underwent CAG at a single tertiary care hospital. We investigatedwhether RWMA observed on 2DE predicted patient outcomes more accurately than did STEobserved on ECG. The primary outcome was incidence of hospital mortality. The secondaryoutcomes were Glasgow-Pittsburgh Cerebral Performance Category scores measured 6months after discharge and significant coronary artery stenosis on CAG. Results: Among the 145 patients, 36 (24.8%) experienced in-hospital death. In multivariableanalysis of survival outcomes, only total arrest time (P=0.011) and STE (P=0.035) were significant. The odds ratio (OR) and 95% confidence interval (CI), which were obtained by adjustingthe total arrest time for survival outcomes, were significant only for STE (OR, 0.40;95% CI, 0.17–0.94). The presence of RWMA was not a significant factor. Conclusions: While STE predicted survival outcomes in adult CA patients, RWMA did not. Thedecision to perform CAG after CA should include ECG under existing guidelines. The use ofRWMA has limited benefits in treatment of this population.

참고문헌 (32)

  1. Spaulding CM, "Immediate coronary angiography in survivors of out-of-hospital cardiac arrest", N Engl J Med, 336, pp.1629~1633 (1997)
  2. Lemkes JS, "Coronary angiography after cardiac arrest without ST-segment elevation", N Engl J Med, 380, pp.1397~1407 (2019)
  3. Jentzer JC, "Early coronary angiography and percutaneous coronary intervention are associated with improved outcomes after out of hospital cardiac arrest", Resuscitation, 123, pp.15~21 (2018)
  4. Reynolds JC, "Coronary angiography predicts improved outcome following cardiac arrest : propensity-adjusted analysis", J Intensive Care Med, 24, pp.179~186 (2009)
  5. Callaway CW, "Part 8: Post-Cardiac Arrest Care: 2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care", Circulation, 132(18 Suppl 2), pp.S465~S482 (2015)
  6. Cannon CP, "Comparison of early invasive and conservative strategies in patients with unstable coronary syndromes treated with the glycoprotein IIb", IIIa inhibitor tirofiban, 2001, pp.344, 1879~1887
  7. Stone GW, "Comparison of angioplasty with stenting, with or without abciximab, in acute myocardial infarction", N Engl J Med, 346, pp.957~966 (2002)
  8. Roe MT, "Treatments, trends, and outcomes of acute myocardial infarction and percutaneous coronary intervention", J Am Coll Cardiol, 56, pp.254~263 (2010)
  9. Kern KB, "Outcomes of comatose cardiac arrest survivors with and without ST-segment elevation myocardial infarction : importance of coronary angiography", JACC Cardiovasc Interv, 8, pp.1031~1040 (2015)
  10. Dumas F, "Immediate percutaneous coronary intervention is associated with better survival after out-of-hospital cardiac arrest : insights from the PROCAT(Parisian Region Out of hospital Cardiac ArresT)registry", Circ Cardiovasc Interv, 3, pp.200~207 (2010)
  11. Dumas F, "Emergency percutaneous coronary intervention in post-cardiac arrest patients without ST-segment elevation pattern : insights from the PROCAT II registry", JACC Cardiovasc Interv, 9, pp.1011~1018 (2016)
  12. Aurore A, "Predictive factors for positive coronary angiography in outof-hospital cardiac arrest patients", Eur J Emerg Med, 18, pp.73~76 (2011)
  13. Sabia P, "Value of regional wall motion abnormality in the emergency room diagnosis of acute myocardial infarction: a prospective study using two-dimensional echocardiography", Circulation, 84(3 Suppl), pp.I85~I92 (1991)
  14. Horowitz RS, "Immediate diagnosis of acute myocardial infarction by two-dimensional echocardiography", Circulation, 65, pp.323~329 (1982)
  15. American College of Cardiology Foundation Appropriate Use Criteria Task Force, "ACCF", ASE, ASNC, pp.HFSA, HRS[DOI]
  16. Bro-Jeppesen J, "Emergency coronary angiography in comatose cardiac arrest patients: do real-life experiences support the guidelines?", Eur Heart J Acute Cardiovasc Care, 1, pp.291~301 (2012)
  17. Langhelle A, "Recommended guidelines for reviewing, reporting, and conducting research on post-resuscitation care: the Utstein style", Resuscitation, 66, pp.271~283 (2005)
  18. Jacobs I, "Cardiac arrest and cardiopulmonary resuscitation outcome reports: update and simplification of the Utstein templates for resuscitation registries: a statement for healthcare professionals from a task force of the International Liaison Committee on Resuscitation (American Heart Association, European Resuscitation Council, Australian Resuscitation Council, New Zealand Resuscitation Council, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Councils of Southern Africa)", Circulation, 110, pp.3385~3397 (2004)
  19. Kim YJ, "Immediate versus early coronary angiography with targeted temperature management in out-of-hospital cardiac arrest survivors without ST-segment elevation : a propensity scorematched analysis from a multicenter registry", Resuscitation, 135, pp.30~36 (2019)
  20. Ryoo SM, "Predicting outcome with diffusion-weighted imaging in cardiac arrest patients receiving hypothermia therapy : multicenter retrospective cohort study", Crit Care Med, 43, pp.2370~2377 (2015)
  21. Neglia D, "Detection of significant coronary artery disease by noninvasive anatomical and functional imaging", Circ Cardiovasc Imaging, 8, pp.e002179~ (2015)
  22. Maddox TM, "Nonobstructive coronary artery disease and risk of myocardial infarction", JAMA, 312, pp.1754~1763 (2014)
  23. Cerqueira MD, "A statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association", Circulation, 105, pp.539~542 (2002)
  24. Thygesen K, "Fourth Universal Definition of Myocardial Infarction(2018)", J Am Coll Cardiol, 72, pp.2231~2264 (2018)
  25. Booth CM, "Is this patient dead, vegetative, or severely neurologically impaired? Assessing outcome for comatose survivors of cardiac arrest", JAMA, 291, pp.870~ (2004)
  26. Cronier P, "Impact of routine percutaneous coronary intervention after out-of-hospital cardiac arrest due to ventricular fibrillation", Crit Care, 15, pp.R122~ (2011)
  27. Noc M, "Invasive coronary treatment strategies for out-ofhospital cardiac arrest : a consensus statement from the European association for percutaneous cardiovascular interventions(EAPCI)", stent for life(SFL)groups, 2014, pp.10, 31~37
  28. Millin MG, "Patients without ST elevation after return of spontaneous circulation may benefit from emergent percutaneous intervention : a systematic review and meta-analysis", Resuscitation, 108, pp.54~60 (2016)
  29. Wester A, "Coronary angiographic findings and outcomes in patients with sudden cardiac arrest without ST-elevation myocardial infarction : a SWEDEHEART study", Resuscitation, 126, pp.172~178 (2018)
  30. Ghadri JR, "International Expert Consensus Document on Takotsubo Syndrome (Part II): Diagnostic Workup, Outcome, and Management", Eur Heart J, 39, pp.2047~2062 (2018)
  31. Chang WT, "Postresuscitation myocardial dysfunction : correlated factors and prognostic implications", Intensive Care Med, 33, pp.88~95 (2007)
  32. Cha KC, "Echocardiographic patterns of postresuscitation myocardial dysfunction", Resuscitation, 124, pp.90~95 (2018)

관련 논문AI추천

Combined ECG, Echocardiographic, and Biomarker Criteria for Diagnosing Acute Myocardial Infarction in Out-of-Hospital Cardiac Arrest Patients김종윤, 박희남, 엄재선, 이문형, 이상은, 정보영연세대학교의과대학 · Yonsei Medical Journal2015 · 제56권 제4호Moderate to Severe Left Ventricular Ejection Fraction Related to Short-term Mortality of Patients with Post-cardiac Arrest Syndrome after Out-of-Hospital Cardiac Arrest김진주, 우재혁, 임용수, 황인철, Hyuk Jun Yang, Keun Lee, Kyoung Jeen Min대한중환자의학회 · Acute and Critical Care2016 · 제31권 제4호Accuracy of Two-Dimensional Speckle Tracking Echocardiography for the Detection of Significant Coronary StenosisAshraf M. Anwar한국심초음파학회 · Journal of Cardiovascular Imaging2013 · 제21권 제4호병원외 심정지 후 집중치료실에 입원한 환자의 예후: 심장성과 비심장성 심정지 비교강환석, 김준식, 김지혜, 백진휘, 이훈재, 조재화, 한승백대한중환자의학회 · Acute and Critical Care2010 · 제25권 제4호Role of Quantitative Wall Motion Analysis in Patients with Acute Chest Pain at Emergency Department김경희, 나상훈, 박진식한국심초음파학회 · Journal of Cardiovascular Imaging2017 · 제25권 제1호Echocardiographic Predictors for Left Ventricular Remodeling after Acute ST Elevation Myocardial Infarction with Low Risk Group: Speckle Tracking Analysis김용진, 김형관, 나현민, 손대원, 윤연이, 이승표, 이주명, 조구영한국심초음파학회 · Journal of Cardiovascular Imaging2016 · 제24권 제2호

이 간행물의 다른 논문 (12건)