Role of Quantitative Wall Motion Analysis in Patients with Acute Chest Pain at Emergency Department
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Background: Evaluation of acute chest pain in emergency department (ED), using limited resource and time, is still very difficultdespite recent development of many diagnostic tools. In this study, we tried to determine the applicability of new semi-automatedcardiac function analysis tool, velocity vector imaging (VVI), in the evaluation of the patients with acute chest pain in ED. Methods: We prospectively enrolled 48 patients, who visited ED with acute chest pain, and store images to analyze VVI fromJuly 2005 to July 2007. Results: In 677 of 768 segments (88%), the analysis by VVI was feasible among 48 patients. Peak systolic radial velocity (Vpeak)and strain significantly decreased according to visual regional wall motion abnormality (Vpeak, 3.50 ± 1.34 cm/s for normal vs. 3.46 ± 1.52 cm/s for hypokinesia, 2.51 ± 1.26 for akinesia, p < 0.01; peak systolic radial strain -31.74 ± 9.15% fornormal,-24.33 ± 6.28% for hypokinesia, -20.30 ± 7.78% for akinesia, p < 0.01). However, the velocity vectors at the time of mitral valveopening (MVO) were directed outward in the visually normal myocardium, inward velocity vectors were revealed in the visuallyakinetic area (VMVO, -0.85 ± 1.65 cm/s for normal vs. 0.10 ± 1.46 cm/s for akinesia, p < 0.001). At coronary angiography, VMVOclearly increased in the ischemic area (VMVO, -0.88+1.56 cm/s for normal vs. 0.70 + 2.04 cm/s for ischemic area, p < 0.01). Conclusion: Regional wall motion assessment using VVI showed could be used to detect significant ischemia in the patientwith acute chest pain at ED.
Abstract
Background: Evaluation of acute chest pain in emergency department (ED), using limited resource and time, is still very difficultdespite recent development of many diagnostic tools. In this study, we tried to determine the applicability of new semi-automatedcardiac function analysis tool, velocity vector imaging (VVI), in the evaluation of the patients with acute chest pain in ED. Methods: We prospectively enrolled 48 patients, who visited ED with acute chest pain, and store images to analyze VVI fromJuly 2005 to July 2007. Results: In 677 of 768 segments (88%), the analysis by VVI was feasible among 48 patients. Peak systolic radial velocity (Vpeak)and strain significantly decreased according to visual regional wall motion abnormality (Vpeak, 3.50 ± 1.34 cm/s for normal vs. 3.46 ± 1.52 cm/s for hypokinesia, 2.51 ± 1.26 for akinesia, p < 0.01; peak systolic radial strain -31.74 ± 9.15% fornormal,-24.33 ± 6.28% for hypokinesia, -20.30 ± 7.78% for akinesia, p < 0.01). However, the velocity vectors at the time of mitral valveopening (MVO) were directed outward in the visually normal myocardium, inward velocity vectors were revealed in the visuallyakinetic area (VMVO, -0.85 ± 1.65 cm/s for normal vs. 0.10 ± 1.46 cm/s for akinesia, p < 0.001). At coronary angiography, VMVOclearly increased in the ischemic area (VMVO, -0.88+1.56 cm/s for normal vs. 0.70 + 2.04 cm/s for ischemic area, p < 0.01). Conclusion: Regional wall motion assessment using VVI showed could be used to detect significant ischemia in the patientwith acute chest pain at ED.
참고문헌 (17)
- Selker HP, "Use of the acute cardiac ischemia time-insensitive predictive instrument (ACI-TIPI) to assist with triage of patients with chest pain or other symptoms suggestive of acute cardiac ischemia. A multicenter, controlled clinical trial", Ann Intern Med, 129, pp.845~855 (1998)
- Pope JH, "Missed diagnoses of acute cardiac ischemia in the emergency department", N Engl J Med, 342, pp.1163~1170 (2000)
- Than M, "A 2-h diagnostic protocol to assess patients with chest pain symptoms in the Asia-Pacific region (ASPECT): a prospective observational validation study", Lancet, 377, pp.1077~1084 (2011)
- Lang RM, "American Society of Echocardiography’s Guidelines and Standards Committee; European Association of Echocardiography. Recommendations for chamber quantification: a report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology", J Am Soc Echocardiogr, 18, pp.1440~1463 (2005)
- Voigt JU, "Strain-rate imaging during dobutamine stress echocardiography provides objective evidence of inducible ischemia", Circulation, 107, pp.2120~2126 (2003)
- Langeland S, "Experimental validation of a new ultrasound method for the simultaneous assessment of radial and longitudinal myocardial deformation independent of insonation angle", Circulation, 112, pp.2157~2162 (2005)
- Cannesson M, "Velocity vector imaging to quantify ventricular dyssynchrony and predict response to cardiac resynchronization therapy", Am J Cardiol, 98, pp.949~953 (2006)
- Kim DH, "Velocity vector imaging in the measurement of left ventricular twist mechanics: head-to-head one way comparison between speckle tracking echocardiography and velocity vector imaging", J Am Soc Echocardiogr, 22, pp.1344~1352 (2009)
- Nesto RW, "The ischemic cascade: temporal sequence of hemodynamic, electrocardiographic and symptomatic expressions of ischemia", Am J Cardiol, 59, pp.23C~30C (1987)
- Sasaki H, "Utility of echocardiography for the early assessment of patients with nondiagnostic chest pain", Am Heart J, 112, pp.494~497 (1986)
- Grenne B, "Acute coronary occlusion in non-ST-elevation acute coronary syndrome: outcome and early identification by strain echocardiography", Heart, 96, pp.1550~1556 (2010)
- Kukulski T, "Identification of acutely ischemic myocardium using ultrasonic strain measurements. A clinical study in patients undergoing coronary angioplasty", J Am Coll Cardiol, 41, pp.810~819 (2003)
- Edvardsen T, "Quantitative assessment of intrinsic regional myocardial deformation by Doppler strain rate echocardiography in humans: validation against threedimensional tagged magnetic resonance imaging", Circulation, 106, pp.50~56 (2002)
- Urheim S, "Myocardial strain by Doppler echocardiography. Validation of a new method to quantify regional myocardial function", Circulation, 102, pp.1158~1164 (2000)
- Asanuma T, "Spatial extent of postsystolic thickening during myocardial ischemia: evaluation by velocity vector imaging", J Echocardiogr, 4, pp.84~85 (2006)
- Claus P, "Mechanisms of postsystolic thickening in ischemic myocardium: mathematical modelling and comparison with experimental ischemic substrates", Ultrasound Med Biol, 33, pp.1963~1970 (2007)
- Masuda K, "Assessment of dyssynchronous wall motion during acute myocardial ischemia using velocity vector imaging", JACC Cardiovasc Imaging, 1, pp.210~220 (2008)
